Ethyl 2-[(tert-butoxycarbonyl)amino]-1,3-thiazole-5-carboxylate

Ugh! This is the name of an organic chemical, "Ethyl 2 - [ (tert-butoxycarbonyl) amino] -1,3 -thiazole-5 -carboxylic acid ester". To clarify its chemical structure, it is necessary to analyze it according to its name.
"Ethyl" is an alkyl group containing two carbon atoms, expressed as "-C ² H", which is often a part of an ester group. " In 2 - [ (tert-butoxycarbonyl) amino] "," tert-butoxycarbonyl "is a protective group with the structure of -COOC (CH < unk >) < unk >, and" amino "is -NH < unk >, and the two are connected to the second position of the thiazole ring." 1,3-thiazole "is a five-membered heterocycle, which contains a sulfur atom and a nitrogen atom, and the nitrogen atom is located at the 1st position and the sulfur atom is located at the 3rd position." 5-carboxylate ", that is, the fifth position of the thiazole ring is connected with a carboxylic acid ester group, which is connected to the previous" ethyl group "to form the -COOCH < unk > CH < unk > structure.
In summary, the chemical structure of this compound is based on a 1,3-thiazole ring, with [ (tert-butoxycarbonyl) amino] at the 2nd position and ethyl carboxylic acid ester at the 5th position, and the parts are connected accordingly to form the overall structure of this organic compound.

Ethyl 2 - [ (tert - butoxycarbonyl) amino] -1,3 - thiazole - 5 - carboxylate is an important compound in organic synthesis. Its main uses are roughly the following ends.
First, in the field of pharmaceutical chemistry, it is often used as a key intermediate. Due to its unique structure, it can introduce different functional groups through various chemical reactions to construct molecular structures with specific pharmacological activities. Compounds derived from carefully designed synthetic routes may have many pharmacological properties such as antibacterial, anti-inflammatory, and anti-tumor, laying the foundation for the development of new drugs.
Second, in the field of materials science, it also has extraordinary performance. Using this compound as a starting material, through specific polymerization reactions or modification methods, materials with special properties can be prepared. For example, some polymer materials involved in the synthesis may have unique optical and electrical properties, and can be used as raw materials for luminescent materials and conductive polymers in the field of optoelectronics, broadening the boundaries of material applications.
Third, in the study of organic synthesis methodologies, Ethyl 2 - [ (tert - butoxycarbonyl) amino] -1,3 - thiazole - 5 - carboxylate is often an important model substrate. By studying their reactions with different reagents, chemists have explored novel reaction pathways and mechanisms, thus developing more efficient and green organic synthesis strategies and promoting the progress of organic synthesis chemistry.

Ethyl + 2 - [ (tert - butoxycarbonyl) amino] - 1,3 - thiazole - 5 - carboxylate, that is, 2 - (tert-butoxycarbonyl amino) - thiazole - 5 - ethyl carboxylate, the synthesis method is as follows:
The starting material can be selected from a suitable sulfur-containing compound and a nitrogen-containing compound, and the thiazole ring is constructed by condensation reaction. For example, using 2-amino-5-bromothiazole and tert-butyl chloroformate as raw materials, in the presence of a suitable base (such as triethylamine), in a suitable organic solvent (such as dichloromethane), the amino group can be protected by tert-butoxycarbonyl to produce 2- (tert-butoxycarbonyl amino) -5-bromothiazole.
Then, the product is cyanosubstituted with reagents such as cuprous cyanide under heating conditions, and a cyano group is introduced to obtain 2- (tert-butoxycarbonyl amino) -5-cyanothiazole. Next, a hydrolysis reaction is carried out under the catalysis of an acid (such as hydrochloric acid) or a base (such as sodium hydroxide) to convert the cyanyl group to a carboxyl group. Finally, in the presence of a catalyst such as concentrated sulfuric acid, an esterification reaction with ethanol can be performed to obtain Ethyl + 2 - [ (tert - butoxycarbonyl) amino] - 1,3 - thiazole - 5 - carboxylate.
Another strategy is to construct a thiazole ring with suitable substituents, and then gradually introduce tert-butoxycarbonyl amino and ester groups. For example, using 2-mercapto-3-aminothiazole as the starting material, first react with ethyl chloroformate to form an ester group, and then react with tert-butyl chloroformate to introduce tert-butoxycarbonyl amino group. In each step of the reaction, attention should be paid to the control of reaction conditions, such as temperature, reaction time, proportion of reactants, etc., to ensure the smooth progress of the reaction and high yield of the product.

Ethyl 2- [ (tert-butoxycarbonyl) amino] -1, 3-thiazole-5-carboxylate, is one of the organic compounds. Its physical and chemical properties are quite specific.
Looking at its physical properties, under normal conditions, it may appear in a solid state. The number of melting points is crucial in the control of organic synthesis reactions. The characteristics of its melting point can help chemists determine its purity and are an important basis for controlling the reaction process. If the melting point range is narrow, it shows that its purity is quite high; if the melting point range is wide, the purity is worrying, or impurities are mixed in it.
As for its solubility, it may have different behaviors in organic solvents, such as common ethanol and dichloromethane. In ethanol, or due to intermolecular forces, it can dissolve to a certain extent, which is due to the interaction between its molecular structure and ethanol molecules, such as hydrogen bonds. In water, due to the existence of hydrophobic groups in the molecule, the solubility is poor, and the capping water is a polar solvent, which repels the hydrophobic part of the compound.
In terms of its chemical properties, the tert-butoxycarbonyl amino group and carboxyethyl ester group contained in the molecule are both reactive. tert-butoxycarbonyl amino group can deprotect under suitable conditions, which is extremely important in the field of peptide synthesis and other fields. By adjusting the reaction conditions, such as temperature, pH and the use of catalysts, the reaction can be precisely regulated to achieve specific synthetic purposes. Carboxyl ethyl ester groups can participate in reactions such as hydrolysis. In acidic or basic environments, ester bonds can be broken to form corresponding carboxylic acids and alcohols. Hydrolysis under basic conditions is faster because hydroxide ions can promote ester bond fracture. In addition, the thiazole ring structure of the compound also gives it certain chemical stability and unique reactivity, which can participate in the characteristic reactions of various heterocyclic compounds, providing a variety of pathways for organic synthesis.

I haven't heard of this price in the market. Those covering "Ethyl 2 - [ (tert - butoxycarbonyl) amino] -1,3 - thiazole - 5 - carboxylate" are key intermediates in organic synthesis, and their prices often vary depending on purity, quantity, and supply and demand.
If you want to find its price, you need to look at all the factors. First of all, the price of high purity is expensive, because it is difficult to prepare and complicated to purify. Look at the quantity again, the purchase price or discount in bulk, and the price of small retail is high. And supply and demand, when the supply exceeds the demand, the price decreases, and if the supply exceeds the demand, the price rises.
And its preparation process also affects the price. If the process is simple, the cost is low, and the price is also low; if the process is difficult, the cost is high, and the price is expensive.
Furthermore, the pricing of different merchants is different. Large merchants may be able to sell at a lower price due to economies of scale; small merchants may be able to sell at a lower price due to high operating costs.
Therefore, if you want to know the market price of this product, you should carefully consider all factors and consult the chemical raw material suppliers to determine the number.