Ethyl 2 Methyl 1 3 Thiazole 5 Carboxylate
quinoline thiophene imidazole thiazole

ethyl 2-methyl-1,3-thiazole-5-carboxylate

    Specifications

    HS Code

    908270

    Chemical Formula C7H9NO2S
    Molecular Weight 171.22 g/mol
    Appearance Typically a solid or viscous liquid
    Physical State At Room Temperature Solid or liquid
    Odor Characteristic odor
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in many organic solvents
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    Frequently Asked Questions

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    Ethyl 2-methyl-1, what is the chemical structure of 3-thiazole-5-carboxylate
    Ethyl 2 - methyl - 1,3 - thiazole - 5 - carboxylate, this is an organic compound. Its chemical structure is composed of three key fragments.
    The first is the thiazole ring, which is a five-membered heterocyclic structure composed of two heteroatoms, namely a nitrogen atom, a sulfur atom, and three carbon atoms connected to each other. This ring has a unique electron cloud distribution and chemical activity, and often plays a key role in many organic reactions and bioactive substances.
    The second is the methyl group located at the second position of the thiazole ring. Methyl is a simple alkyl group containing only one carbon atom and three hydrogen atoms. Adhering to the thiazole ring will affect the electron cloud density around the thiazole ring, which in turn changes the physical and chemical properties of the whole molecule, such as affecting the polarity of the molecule, steric hindrance, etc. The end of
    is a carboxylic acid ethyl ester group connected at position 5. This group is derived from the esterification reaction of carboxylic groups and ethanol. Among the carboxylic acid ethyl ester groups, the carbonyl group (C = O) has strong electronegativity, which together with the oxygen atom in the ester group shapes the unique electronic environment. At the same time, the long chain structure of the ethyl ester group also affects the solubility, stability and interaction mode of the whole molecule with other molecules. The chemical structure of this compound, due to the synergistic effect of various partial groups, endows it with specific physicochemical properties and potential chemical reactivity, and may have important application value in the fields of organic synthesis, medicinal chemistry, etc.
    What are the main uses of ethyl 2-methyl-1, 3-thiazole-5-carboxylate
    Ethyl-2-methyl-1,3-thiazole-5-carboxylic acid ester, which has a wide range of uses. In the field of medicine, it is often a key intermediate for the synthesis of various drugs. For example, when creating antibacterial drugs, its unique structure can be cleverly modified to obtain compounds with strong antibacterial activity, which adds to the fight against pathogens. In the field of pesticides, it also has important uses and is an important starting material for the synthesis of highly efficient and low-toxic pesticides. After chemical transformation, it can generate agents with high-efficiency pest control effects, which can help agricultural harvests and protect the healthy growth of crops. In addition, in the field of fine chemicals, it can be used as a raw material for the synthesis of special functional materials, which show unique properties in paints, fragrances and other industries, adding characteristics and value to products. Due to its chemical structure, it plays an important role in many fields and promotes the development of various industries.
    What are the synthesis methods of ethyl 2-methyl-1, 3-thiazole-5-carboxylate
    There are several common methods for synthesizing 2-methyl-1,3-thiazole-5-carboxylic acid ethyl ester.
    First, 2-methyl-1,3-thiazole-5-carboxylic acid is used as the starting material to esterify it with ethanol under acid catalysis. This process needs to be carried out at a suitable temperature and reaction time. Usually concentrated sulfuric acid or p-toluenesulfonic acid is selected as the catalyst, and under the condition of heating and reflux, the two react to form the target product 2-methyl-1,3-thiazole-5-carboxylic acid ethyl ester. After the reaction is completed, the product is purified through neutralization, extraction, distillation and other steps.
    Second, the compound containing thiazole ring and ethyl haloacetate are used as raw materials. First, the compound containing thiazole ring interacts with the base to generate the corresponding negative ion, which then undergoes nucleophilic substitution reaction with ethyl haloacetate to construct the structure of the target molecule. For example, 2-methyl-5-halothiazole and ethyl haloacetate are reacted in a suitable organic solvent in the presence of a base. Commonly used bases include potassium carbonate, sodium hydride, etc. Organic solvents can be selected from N, N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), etc. After the reaction, the product can be obtained by separation and purification.
    Third, a multi-step reaction strategy can be adopted. First, the thiazole ring structure is constructed, and then the carboxyl ethyl ester group is introduced. For example, with appropriate sulfur-containing compounds, carbonyl compounds and ammonia (or amine) compounds, the thiazole ring is constructed by condensation reaction, and then a series of reactions, such as halogenation, carboxylation, esterification, etc., are followed to obtain 2-methyl-1,3-thiazole-5-carboxylic acid ethyl ester. Each step requires fine control of the reaction conditions to ensure the smooth progress of the reaction and the purity and yield of the product.
    What are the physical properties of ethyl 2-methyl-1, 3-thiazole-5-carboxylate?
    Ethyl + 2 - methyl - 1,3 - thiazole - 5 - carboxylate is 2 - methyl - 1,3 - thiazole - 5 - carboxylate, which is an organic compound. Its physical properties are as follows:
    Viewed at room temperature, it is mostly colorless to light yellow liquid, and its texture is clear and translucent. With the sense of smell, it often has a special smell, but this smell is not pungent and intolerable, and it is still acceptable.
    When it comes to the boiling point, its boiling point is in a specific temperature range, which is determined by factors such as intermolecular forces. Generally speaking, under appropriate heating conditions, it will boil and transform into a gaseous state at a certain temperature. The melting point is relatively low, and it does not appear as a solid state at room temperature.
    In terms of solubility, it exhibits good solubility in organic solvents, such as ethanol, ether and other common organic solvents, which can be fused with it, just like fish water. However, in water, its solubility is quite limited. Due to the characteristics of the molecular structure of the compound, it is difficult to form an effective interaction with water molecules, so it is difficult to dissolve in water.
    In terms of density, it is similar to the density of common organic solvents. It is placed in a specific liquid environment, and its location can be observed according to the density difference. In addition, the stability of the compound under specific conditions is also its important physical property. Under general environmental conditions, its chemical structure is relatively stable, and it is not easy to spontaneously produce significant changes.
    Ethyl 2-methyl-1, what is the price range of 3-thiazole-5-carboxylate in the market?
    I think what you are asking is about ethyl + 2 - methyl - 1,3 - thiazole - 5 - carboxylate in the market price range. However, such information is difficult to answer accurately. The price of a market change often varies with many factors.
    First, the situation of supply and demand is also. If the demand for this product is strong and the supply is limited, the price will rise; conversely, if the supply exceeds the demand, the price will decline. Second, the cost of production is also the key. The price of raw materials, the cost of labor, and the difficulty of manufacturing all affect its cost, which in turn affects the price. Third, the competitive situation of the market cannot be underestimated. If the competition in the same industry is fierce, in order to compete for share, there may be a price reduction; if it is in a monopoly situation, the price may be too high.
    And this product may be used in specific fields, such as medicine, chemical industry, etc. The demand characteristics of different industries also make the price different. In addition, the differences in regional markets, taxes, and transportation costs make it difficult to generalize its price. Therefore, to know the exact price range, it is necessary to carefully investigate professional chemical product trading platforms, consult industry experts, or consult relevant production and sales companies to obtain a more accurate figure.