Ethyl 2-Amino-alpha-(methoxyimino)-4-thiazoleacetate

The chemical structure of Ximing "Ethyl + 2 - Amino - alpha - (methoxyimino) - 4 - thiazoleacetate", this name is translated as 2 - amino - α - （ methoxyimino) - 4 - thiazoleacetate ethyl ester.
Looking at its structure, the main frame contains a thiazole ring, which consists of a sulfur atom and a nitrogen atom coexisting in a five-membered ring. At the 4 - position of the thiazole ring, there is a structure of ethyl acetate, which is obtained by the esterification reaction of acetic acid and ethanol, and is in the shape of an ester group - COOCH ² CH, which contains carbonyl and ether bonds.
Furthermore, the α-position of the thiazole ring, that is, the key position connected to the ring, is connected with a methoxy imino group. The methoxy imino group is connected by methoxy-OCH 🥰 and imino = N -, the nitrogen of the imino group is connected to α-carbon by double bond, and the methoxy group is connected to the nitrogen of the imino group.
The 2-position of the thiazole ring is connected to the amino-NH ², and the amino group is nucleophilic and shows its activity in many chemical reactions. In this way, the structure of this compound is composed of thiazole ring, ethyl acetate group, methoxyimino group and amino group, and each part interacts with each other, giving it unique chemical properties and reactivity. It has important research value and application prospects in many fields such as organic synthesis and medicinal chemistry.

Ethyl 2 - Amino - α - ( methoxy imino) -4 - thiazoleacetate, which is 2 - amino - α - （ methoxy imino) - 4 - thiazole ethyl acetate, is widely used. In the field of medicine and chemical industry, it is a key intermediate, mostly involved in the synthesis of cephalosporins antibiotics. Cephalosporins antibiotics can hinder the synthesis of bacterial cell walls, show powerful bactericidal effect in the breeding period of bacteria, and are clinically used to treat a variety of bacterial infections, such as respiratory tract infections, urinary tract infections, skin and soft tissue infections. Ethyl 2 - Amino - α - ( methoxy imino) -4 - thiazoleacetate plays an important role in the synthesis of such antibiotics, which is related to the quality and performance of the product.
In the field of organic synthesis, due to its structure containing specific functional groups, it can participate in a variety of organic reactions, such as nucleophilic substitution, condensation, etc. Through these reactions, chemists can create organic compounds with complex structures and specific functions, paving the way for the development of new drugs and the creation of new materials. For example, when developing new antibacterial drugs, it can be used as a starting material and modified through a series of reactions to obtain compounds with novel structures and excellent antibacterial activities.
In addition, in agricultural chemicals, it may be a new type of pesticide intermediate for synthesis. With the development of agriculture, there is an increasing demand for high-efficiency, low-toxicity and environmentally friendly pesticides. Ethyl 2 - Amino - α - ( methoxy imino) -4 - thiazoleacetate may be converted into pesticides with insecticidal, bactericidal or herbicidal properties through specific reactions, which can help agricultural pest control and crop growth.

There are various ways to synthesize Ethyl + 2 - Amino - alpha - (methoxyimino) - 4 - thiazoleacetate. One common way is to start with ethyl 4 - chloroacetoacetate, through the steps of condensation and cyclization. First, ethyl 4 - chloroacetoacetate and thiourea are combined in a suitable solvent, such as ethanol, and catalyzed by adding a base to carry out a condensation reaction to form ethyl 2 - amino - 4 - thiazoleacetate. Then, the product reacts with methoxylamine hydrochloride in an organic solvent in the presence of a base to convert the carbonyl group to methoxyimino, resulting in Ethyl + 2 - Amino - alpha - (methoxyimino) - 4 - thiazoleacetate.
There is another synthesis method, using ethyl acetoacetate as the initial material. Schilling ethyl acetoacetate reacts with thiourea to obtain an analogue of 2 - amino - 4 - thiazole ethyl acetate. Thereafter, methoxyimino is introduced through a series of reactions such as halogenation and substitution. During halogenation, suitable halogenating agents, such as thionyl chloride, are often selected to halogenate specific locations. Then the halogen atom is replaced by methoxyamine reagents to obtain the target product.
Another way is to start from thiazole derivatives and modify the side chain to introduce amino groups, methoxyimino groups and ethyl ester groups. Select an appropriate thiazole substrate and gradually build the desired molecular structure by means of organic synthesis, such as nucleophilic substitution, oxidation, reduction and other reactions. This process requires fine regulation of reaction conditions, such as temperature, pH, reaction time, etc., in order to achieve the ideal yield and purity.
All these synthesis methods have their own advantages and disadvantages, and should be selected according to actual needs, such as raw material availability, cost, yield and product purity.

Ethyl 2 - Amino - α - ( methoxy imino) -4 - thiazoleacetate is an organic compound, which is very important in the field of chemistry. Its physical properties are as follows:
In terms of appearance, this compound is usually in the state of white to white crystalline powder, with fine texture and a certain luster under light. This morphological feature is easy to identify and deal with in production and experiments.
When it comes to melting point, it is generally in a specific temperature range, about 100 ° C - 110 ° C. The melting point is an inherent characteristic of the substance, which is of great significance for the identification of its purity. If Ethyl 2 - Amino - α - ( methoxy imino) -4 - thiazoleacetate has high purity, the melting point is acute and the melting range is narrow; if it contains impurities, the melting point is reduced and the melting range is widened.
In terms of solubility, it exhibits different solubility characteristics in organic solvents. In common alcoholic solvents such as methanol and ethanol, it has good solubility and can form a homogeneous solution. This is due to the interaction between molecules and alcoholic solvents. In water, the solubility is relatively limited, due to the influence of hydrophobic groups in the molecular structure, the affinity with water is reduced.
In addition, the density of Ethyl 2 - Amino - α - ( methoxy imino) -4 - thiazoleacetate is also one of its physical properties. Although there is no exact and widely reported value, density considerations are indispensable in chemical production involving material measurement, storage container design, etc., which are related to the accuracy and safety of the production process.
Ethyl 2 - Amino - α - ( methoxy imino) -4 - thiazoleacetate The above physical properties have far-reaching effects on the selection of reaction conditions, product separation and purification in organic synthesis, drug development and other fields, and require detailed attention from researchers and producers.

Ethyl+2-Amino-alpha-%28methoxyimino%29-4-thiazoleacetate, that is, 2-amino-alpha - (methoxyimino) -4-thiazole ethyl acetate, this substance is in the field of medicine and chemical industry, and plays a crucial role. It is often the key intermediate for the synthesis of cephalosporins.
Looking at its market prospects, with the continuous rise in global demand for antibiotics, cephalosporins are widely used in clinical anti-infective drugs, and their market scale is steadily expanding. As a necessary raw material for the synthesis of such antibiotics, the demand for this intermediate is also rising.
From the perspective of pharmaceutical research and development, the research and development process of new cephalosporins continues to advance, putting forward higher requirements for the quality and performance of intermediates. In order to meet market demand, enterprises and scientific research institutions are committed to technological innovation and process optimization, and strive to improve product quality and production efficiency. The market competition for this intermediate is also becoming increasingly fierce, which also brings opportunities for technological upgrading and industrial development.
In terms of global market layout, the Asia-Pacific region has become an important consumer market for such intermediates due to its large population, rapid economic growth and continuous release of medical demand. At the same time, some developing countries have gradually emerged as important production bases for intermediates by virtue of their cost advantages, intensifying the multi-competition landscape of the market.
Overall, the market prospect of 2-amino-alpha- (methoxyimino) -4-thiazole ethyl acetate is quite promising, but it also faces many challenges such as technological upgrading and market competition. Industry players need to take advantage of the situation in order to gain an advantage in the market.