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What is the chemical structure of Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate?
Eh, this "Ethyl + 2 - amino - 4 - phenyl - 5 - thiazolecarboxylate" is the name of the organic compound. If you want to know its chemical structure, let me tell you in detail.
In the name of this compound, "Ethyl", ethyl is also called, and its structure is -CH ² CH 🥰, which seems to be the base of a short URL, attached elsewhere. "2 - amino" means that the amino group is connected to the No. 2 position of the main structure. Amino, -NH ², is also active and is often the key in organic reactions. < Br >
"4-phenyl", which means that the benzene ring is connected to the 4th position of the main structure. The benzene ring is a six-membered ring structure with special stability due to its conjugate system. The benzene ring structure is connected by six carbon atoms with special bonds, shaped like a regular hexagon, and each carbon atom can be connected to other groups.
"5-thiazolecarboxylate" indicates that the thiazolecarboxylate ring is the main structure, and there is a carboxyl ester group connected at the 5th position. The thiazolecarboxylate ring is a five-membered heterocycle containing sulfur and nitrogen, and its structure is unique, with sulfur atoms and nitrogen atoms in specific positions. The ester group of the carboxyl group, that is, -COO-R, where R is ethyl.
Together, this compound has a thiazole ring as the core, with an amino group at the 2nd position, a benzene ring at the 4th position, and a carboxyl ester group containing an ethyl group at the 5th position. In this way, its chemical structure can be clearly identified. Its structure design is exquisite, and its parts interact, or it has unique chemical and physical properties. It may have extraordinary applications in the fields of organic synthesis and medicinal chemistry.
What are the main uses of Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate?
Ethyl-2-amino-4-phenyl-5-thiazole carboxylate, an organic compound, has a wide range of uses and is of great value in many fields.
In the field of medicinal chemistry, it is often used as a key intermediate in drug synthesis. The development and preparation of many drugs rely on this compound as a starting material. After a series of chemical reactions, drug molecules with specific pharmacological activities can be derived, such as the synthesis of some antibacterial and anti-inflammatory drugs. Ethyl-2-amino-4-phenyl-5-thiazole carboxylic acid esters may play an important role in the synthesis of active ingredients with unique structures and functions to deal with various diseases.
In the field of materials science, it may be beneficial to the improvement of the properties of specific materials. For example, in the preparation of some polymer materials, the introduction of this compound can change the physical and chemical properties of the material, such as enhancing the stability of the material, improving its optical properties, etc., and then expand the application range of the material in different fields, such as optical materials, high-performance polymer materials, etc.
In agricultural chemistry, it may also have applications. It can be used as a raw material for the synthesis of new pesticides. With its structural characteristics, pesticide products with high insecticidal, bactericidal or herbicidal activities can be developed, contributing to the protection of crops and the improvement of agricultural production, and helping the sustainable development of agriculture.
Furthermore, in the study of organic synthetic chemistry, ethyl-2-amino-4-phenyl-5-thiazole carboxylic acid esters are often important research objects. Chemists can expand the methods and strategies of organic synthesis by in-depth exploration of their reaction characteristics and reaction mechanisms, and contribute to the development of organic chemistry theory and practice, and promote organic synthetic chemistry to new heights.
What are the synthetic methods of Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate?
Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate, that is, ethyl 2-amino-4-phenyl-5-thiazolecarboxylate, has been synthesized in ancient times. Due to the technique of organic synthesis, it has been explored by predecessors after years of precipitation.
One method can start from a suitable aryl acetaldehyde. First, the aryl acetaldehyde interacts with thiourea and ethyl bromopyruvate. In this process, the carbonyl group of aryl acetaldehyde is condensed with the amino group of thiourea. When the ring is formed, the carboxyl ethyl ester part of ethyl bromopyruvate is involved. After a series of reactions, 2-amino-4-phenyl-5-thiazolecarboxylate ethyl ester is formed. When reacting, pay attention to the reaction conditions. The temperature should not be too high, otherwise it is easy to cause side reactions to occur and make the product impure. Usually, at a mild temperature, such as 40-60 degrees Celsius, the reaction can be slowly carried out to ensure the smooth progress of the reaction.
Another method uses phenylacetonitrile as the starting material. First, phenylacetonitrile is converted into the corresponding thioamide, and then reacts with halogenated ethyl acetate. This reaction also forms a ring to form the target product. During this time, the sulfur atom of thioamide interacts with the halogen atom of halogenated ethyl acetate, and through the cyclization step, the thiazole ring structure is formed. The pH of the reaction system needs to be finely regulated, and the alkalinity is too strong or too weak, which affects the reaction process. Generally speaking, an appropriate amount of weak bases, such as potassium carbonate, can maintain the moderate alkalinity of the system, which is conducive to the smooth completion of the reaction.
Furthermore, the reaction of aryl isothiocyanate with ethyl α-halogenated ketoate is also the way of synthesis. The two interact, and through addition and cyclization, ethyl 2-amino-4-phenyl-5-thiazolecarboxylate can be obtained. This process requires a high solvent for the reaction. Non-polar or weakly polar solvents, such as toluene, can make the reaction smoother. And the reaction time also needs to be controlled. If it is too short, the reaction will be incomplete, and if it is too long, impurities may form. It is appropriate to monitor the reaction process in a timely manner according to the actual situation to obtain high-purity products.
What are the physical properties of Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate?
Ethyl 2 - amino - 4 - phenyl - 5 - thiazolecarboxylate, Chinese name ethyl 2 - amino - 4 - phenyl - 5 - thiazolecarboxylate. This material has the following physical properties:
Its properties are often crystalline solids, the appearance is mostly white to off-white, the texture is fine, and the crystalline morphology is regular, due to the orderly arrangement of its molecular structure.
In terms of melting point, it is usually within a certain temperature range, about 160 - 165 ° C. The melting point is relatively fixed due to intermolecular forces and stable lattice energy. When a certain temperature is reached, the lattice is destroyed and the state changes.
Solubility, slightly soluble in water. Water is a polar solvent. Although there are polar groups in the molecules of this substance, the non-polar parts such as phenyl groups account for a large proportion, and the interaction with water to form hydrogen bonds is weak, so it is difficult to dissolve. However, it is soluble in some organic solvents, such as ethanol and chloroform. The polarity of ethanol is adapted to the partial structure of this substance. Chloroform can provide a suitable dissolution environment, and the molecules can be mutually soluble through van der Waals force and other actions.
Its density is higher than that of water, which is of great significance in the field of organic synthesis. In the reaction system, due to its density characteristics, it is obviously divided into layers with water, which is convenient for separation operations, and can be used to achieve product purification and other steps.
In addition, the substance has good stability, and the molecular structure is not easy to change under conventional temperature, light and dry environments Because the structure of thiazole ring and benzene ring endows it with conjugate stability, the amino group interacts with carboxyl ethyl ester and other groups to enhance the overall stability. However, under extreme conditions such as strong acid, strong base or high temperature, the chemical bond will be affected and the structure will be changed.
What is the market outlook for Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate?
Ethyl 2-amino-4-phenyl-5-thiazolecarboxylate is a chemical substance, the Chinese name is 2-amino-4-phenyl-5-thiazolecarboxylate. Looking at its market prospects, there are many things to be said.
In today's pharmaceutical field, there is a hunger for novel and biologically active compounds. This compound may have emerged in the drug development path due to its unique chemical structure. For example, in the exploration of antibacterial drugs, the specificity of its structure may make it fit with the key targets of bacteria and exert the antibacterial effect, just like a precise target in the bullseye, so there is hope for expansion in the antibacterial drug market.
Furthermore, in the field of pesticides, it is the general trend to seek highly efficient and low-toxic pesticide ingredients. This compound may have repellent or killing effects on specific pests due to its own characteristics, and is less harmful to the environment than traditional pesticides. It seems to be gentle and drizzle, and does not harm everything. If the research and development goes well, it will definitely be able to get a share of the pesticide market.
However, its market road is not smooth. R & D costs are high, and it takes a long time to go from laboratory synthesis to large-scale production, requiring huge investment in process optimization and quality control. And the market competition is intense, with similar or alternative compounds emerging in an endless stream. If you want to stand out, you need to have unique advantages, such as lower costs and better results, in order to gain market favor and set sail in the business sea.