ethyl 2-amino-4-methyl-1,3-thiazole-5-carboxylate

Ethyl-2-amino-4-methyl-1,3-thiazole-5-carboxylic acid ester, which has a wide range of uses. In the field of medicine, it is often a key intermediate for the synthesis of various drugs. Its unique chemical structure can endow the drug with specific biological activities and pharmacological properties, or can enhance the affinity of the drug to specific targets and improve the efficacy. For example, in the development of antibacterial drugs, it can participate in the construction of the core structure of the drug, or make the drug more effectively act on the key metabolic pathways or cell structures of bacteria to achieve the purpose of antibacterial.
In the field of pesticides, it also plays an important role. It can be used as a raw material for the synthesis of new pesticides, helping to create pesticide products with high efficiency, low toxicity and environmentally friendly characteristics. For example, pesticides synthesized on this basis can precisely act on specific physiological parts or metabolic links of pests with special structures, killing pests while reducing adverse effects on non-target organisms and the environment.
In the field of materials science, ethyl-2-amino-4-methyl-1,3-thiazole-5-carboxylic acid esters can be used to prepare functional materials. Some groups in its structure may endow materials with special optical, electrical or thermal properties, or new materials with unique properties can be developed for use in electronic devices, optical sensors and other fields.

Fuethyl-2-amino-4-methyl-1,3-thiazole-5-carboxylic acid ester is a kind of organic compound. Its physical properties are very important and are related to its many applications.
First of all, its appearance is often white to white crystalline powder, which makes it easy to identify and handle. Its texture is delicate and smooth to the touch. Under the microscope, a regular crystal structure can be seen.
Second, its melting point is within a certain range. This property is of great significance for its purity identification and processing. The determination of the melting point can help to determine the purity of the compound. If impurities are mixed in, the melting point will often change.
Furthermore, solubility is also a key property. In organic solvents, such as ethanol, acetone, etc., there is a certain solubility, which is convenient for it to participate better in chemical reactions as a reactant or intermediate in organic synthesis reactions. However, in water, its solubility is relatively low. This difference is due to the characteristics of its molecular structure. The hydrophobic groups in the molecule make its interaction with water molecules weak.
also has density, although the specific value depends on accurate measurement, it is roughly within a certain range. This property is very important in application scenarios involving mass and volume conversion. When planning storage and transportation, its density characteristics need to be considered to ensure safety and efficiency.
In addition, the stability of this compound is also worthy of attention. Under normal environmental conditions, it can maintain a relatively stable state. In case of extreme conditions such as high temperature, strong acid, and strong alkali, its structure may change, resulting in changes in chemical properties. From this perspective, the physical properties of ethyl-2-amino-4-methyl-1,3-thiazole-5-carboxylic acid esters are of vital importance in the fields of organic synthesis, drug discovery, and related industrial applications.

The method of preparing ethyl 2-amino-4-methyl-1,3-thiazole-5-carboxylic acid ester has been explored by many scholars in the past. There are many methods, and the important ones are listed below.
First, it starts with sulfur-containing compounds and nitrogen-containing compounds, and goes through the technique of condensation. If thioacetamide meets α-haloketoate, under appropriate temperature and pressure, supplemented by a suitable catalyst, the two are combined. In this process, the sulfur atom of thioacetamide is easy to phase with the halogen atom of α-halogenated ketoate, and the nitrogen atom also participates in the change of cyclization, so the structure of thiazole carboxylic acid ester is obtained. When the temperature is too high, it is necessary to observe the change of temperature. If the temperature is too high, the side reactions will be clustered and the product will be impure; if the temperature is too low, the reaction will be slow and take a long time.
Second, β-ketoate and thiourea can also be used as the base material. First, the β-ketoate and thiourea are miscible in a specific solvent, or mildly, or with catalytic force, so that the two can be condensed first to form an intermediate product. Then, through the cyclization step, the sulfur atom forms a thiazole ring with the adjacent carbon atom and nitrogen atom, and then through the esterification method, ethyl is introduced, and the final ethyl 2-amino-4-methyl-1,3-thiazole-5-carboxylate is obtained. In this path, the properties of the solvent are very critical, and the strength of the polarity and the force of dissolution are all related to the rate of reaction and the purity of the product.
Third, there are also those who use halogenated aldose and thioamide as the starting reactants. After the condensation reaction between halogenated aldodes and thioamides, a chain-like intermediate is initially formed. After the cyclization in the molecule, the synergistic action of sulfur and nitrogen atoms builds a thiazole ring. At the end, the esterification operation is performed, and ethyl is added. In the meantime, the halogen atom activity of halogenated aldodes and the structural characteristics of thioamides all affect the process of the reaction. If you want to get the best effect, you must consider it carefully.
All these production methods have their own advantages and disadvantages. The experimenter should choose carefully according to the raw materials, the desired purity, and the limited time and space, etc., in order to achieve the purpose of preparing this substance.

I don't know if ethyl - 2 - amino - 4 - methyl - 1,3 - thiazole - 5 - carboxylate is in the market price range. Although this compound is useful in the field of chemistry, its market price often changes due to various reasons. Such as the price of raw materials, the difficulty of preparation, the amount of demand, and the balance of supply and demand in the market can all determine its price.
If you want to know more about it, you can go to the chemical raw material trading market, consult merchants, or check the chemical product price information platform, which often records the current price. Or ask people who are experts in the industry, who have been involved in this industry for a long time and are familiar with the market, or can tell you a more accurate price range. Sadly, I can't tell you the price range of this compound directly. I hope you will find something if you follow this path.

Ethyl 2 - amino - 4 - methyl - 1,3 - thiazole - 5 - carboxylate is an organic compound, and its storage conditions need to be carefully considered. This substance should be placed in a cool and dry place. If exposed to high temperature or humidity, it may cause deterioration. High temperature can cause its chemical structure to change, and humidity may cause it to absorb moisture, which in turn affects its purity and stability.
Furthermore, it needs to be stored in a dark place away from light. Many organic compounds are sensitive to light, and under light, or cause luminescent chemical reactions to cause their decomposition or structural changes. Ethyl 2 - amino - 4 - methyl - 1,3 - thiazole - 5 - carboxylate may also pose this risk, so it should be stored in an opaque container and placed in a place where light is difficult to reach.
In addition, when storing, keep away from fire sources and oxidants. Because it is an organic substance, it is flammable, and it is easy to catch fire or even explode in case of fire sources; and oxidants can react violently with it, causing its properties to change, or even causing danger.
At the same time, the storage place should be well ventilated. If the storage space is poorly ventilated, once the material evaporates or leaks, its vapor or accumulation will not only endanger the environment, but also threaten the health and safety of people. < Br >
During the use and storage process, protective measures should also be taken, such as wearing appropriate protective gloves, goggles, etc., to prevent harm to the human body caused by contact or inhalation. Follow the above storage conditions to ensure the quality and stability of ethyl 2-amino-4-methyl-1,3-thiazole-5-carboxylate and avoid accidents.