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What are the chemical properties of Ethyl 2- (3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate (F5)
Ethyl 2- (3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate (F5) is an organic compound. This compound has unique chemical properties. From the structural point of view, it contains a cyanyl group (-CN), and the cyanyl group has high electronegativity, which can make the molecule have a certain polarity, which affects its solubility and reactivity. Because of its polarity, it may have good solubility in polar solvents.
Furthermore, there is a thiazole ring structure in the molecule. The thiazole ring is a five-membered heterocycle containing sulfur and nitrogen, which has a certain aromaticity and gives the molecule special stability and reactivity. Substituents on the thiazole ring, such as 4-methyl and 5-carboxylic acid ethyl ester groups, further affect its chemical properties. The electron cloud density of thiazole ring can be increased by using 4-methyl as the power supply group, which makes it more prone to electrophilic substitution reaction. 5-ethyl carboxylate group is the electron-withdrawing group, which has the opposite effect on the electron cloud density of thiazole ring, and this group can undergo various reactions such as hydrolysis and alcoholysis.
In addition, the 3-cyano group and 4-isobutoxy group on the benzene ring also affect the molecular properties. 3-cyano group enhances molecular polarity, and 4-isobutoxy group is a larger volume substituent, which can produce a steric hindrance effect, which affects the intermolecular interaction and reaction selectivity.
In summary, the chemical properties of Ethyl 2- (3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate (F5) are determined by the interaction of various functional groups and substituents, which make it potentially used in organic synthesis, medicinal chemistry and other fields.
What are the application fields of Ethyl 2- (3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate (F5)
Ethyl 2- (3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate (F5) is an organic compound. This compound has its applications in many fields.
In the field of medicine, it may have potential medicinal value. Cover organic compounds are often key starting materials for drug development. The specific structure of F5 may give it the ability to interact with specific targets in organisms, such as binding with certain proteins and enzymes, thereby regulating physiological processes in organisms, or it can be developed as a drug for the treatment of specific diseases. However, a large number of experiments and studies are required to confirm its efficacy and safety.
In the field of materials science, it may be used to prepare materials with special properties. Organic compounds can be chemically modified and polymerized to construct materials with unique optical, electrical or mechanical properties. The structural characteristics of F5 may make it suitable for the preparation of optical materials that respond to specific wavelengths of light, or for improving the stability and functionality of materials, and for use in electronic devices, optical coatings, etc.
In the field of agricultural chemistry, such compounds may have biological activities such as insecticidal, bactericidal or herbicidal. Some organic compounds can interfere with the physiological and metabolic processes of pests and achieve the purpose of controlling pests and weeds. The structural characteristics of F5, or give it inhibitory effects on specific crop pests or pathogens, are expected to be developed into new pesticides and contribute to sustainable agricultural development. However, its impact on the environment and non-target organisms also needs to be evaluated.
What is the synthesis method of Ethyl 2- (3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate (F5)
Ethyl 2- (3 - cyano - 4 - isobutoxyphenyl) -4 - methyl - 5 - thiazolecarboxylate (F5) is an organic compound. The synthesis method of ethyl 2- (3 - cyano - 4 - isobutoxyphenyl) -4 - methyl - 5 - thiazolecarboxylate (F5) needs to be prepared according to a certain method to synthesize it.
First, all raw materials need to be prepared to find compounds containing corresponding functional groups. If you want to obtain this F5, you need to find the precursors containing cyanyl, isobutoxy, phenyl, methyl, thiazole and carboxyethyl ester structures.
The ancient chemical synthesis method, or the raw materials containing phenyl groups, through substitution reaction, introduce cyano and isobutoxy at specific positions in the phenyl ring. This process requires appropriate reaction conditions, such as selecting suitable catalysts, controlling reaction temperature and time. Or use nucleophilic substitution to react halobenzene with cyanide and isobutoxyphenyl reagents to form a 3-cyano-4-isobutoxyphenyl structure.
Then, synthesize the thiazole ring part. The thiazole ring is formed by cyclization of compounds containing sulfur, nitrogen and carbonyl groups. Or use reagents such as α-halogenated ketone and thiourea to promote cyclization under suitable acid-base conditions to obtain intermediates containing thiazole structures.
Then combine the intermediate containing 3-cyano-4-isobutoxyphenyl with the intermediate containing thiazole structure. Or through esterification and other steps, the two are connected, and methyl is introduced at a specific position of the thiazole ring, and carboxyl ethyl ester is connected at another position to obtain Ethyl 2- (3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate (F5). After each step of the reaction, it needs to be separated and purified to remove impurities and maintain the purity of the product. In this way, according to the above steps and conditions, the principle of chemical synthesis according to the ancient method may lead to this compound.
What is the market outlook for Ethyl 2- (3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate (F5)?
Ethyl 2- (3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate (F5) is a promising compound. There are many considerations in terms of market prospects.
Looking at the field of medicine, there is a great demand for novel and highly effective drugs. If F5 is studied in depth, it may exhibit unique pharmacological activities, such as targeted therapeutic potential for specific diseases. To enter this field, it is necessary to undergo rigorous and complicated clinical trials to prove its safety and effectiveness. This process is time-consuming and expensive, and many compounds have been lost in this process.
In the field of pesticides, it is the general trend to seek green, efficient and low-toxic pesticides. If F5 has unique insecticidal, bactericidal or weeding activities, it is in line with the current concept of sustainable agricultural development, or it can gain a place in the pesticide market. However, it also needs to face fierce competition. Many congeneric products have occupied a certain market share. To stand out, it is necessary to highlight their own advantages, such as better control effects and lower environmental residues.
In the field of materials, with the progress of science and technology, the demand for special performance materials is increasing. If F5 can play a role in material modification, such as improving material stability and optical properties, it is also expected to open up new markets. However, material research and development needs to be closely integrated with downstream industries to ensure that products meet practical application needs.
In summary, although Ethyl 2- (3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate (F5) has promising potential, it is necessary to overcome many difficulties in order to succeed in the market, such as R & D cost control, performance optimization and marketing activities. Only by properly responding can we occupy a favorable position in the market.
Ethyl 2- (3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate (F5) is safe and toxic
Ethyl 2- (3-cyano-4-isobutoxyphenyl) -4-methyl-5-thiazolecarboxylate (F5) is a chemical substance, which is not recorded in "Tiangongkai". Because "Tiangongkai" was written in the Ming Dynasty, the chemistry discipline had not yet developed to the extent that it could study such modern organic compounds.
But from a modern scientific perspective on its safety and toxicity, the safety and toxicity of such organic compounds need to be determined by a series of professional experiments. First, its toxicity research often starts from acute toxicity experiments. By giving different doses of F5 orally, percutaneously or inhaled to experimental animals (such as rats and mice), the poisoning symptoms and death of animals in the short term are observed to determine the half lethal dose (LD50), so as to preliminarily evaluate the degree of acute toxicity.
Followed by chronic toxicity and carcinogenicity experiments, long-term administration of low doses of F5 to experimental animals, observation for several months to several years, monitoring the health status of animals, histopathological changes, and judging whether there is chronic toxicity and carcinogenicity.
In addition, there are genotoxicity experiments to detect whether F5 will cause damage to the genetic material of organisms, such as mutagenicity, which are evaluated by methods such as Ames experiments. Its safety also involves environmental safety, and it is necessary to consider its degradability in the environment and its impact on organisms in the ecosystem. If F5 is difficult to degrade in the environment, it may accumulate in organisms, and then pass through the food chain, affecting ecological balance and human health.