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What is the chemical structure of Ethyl 2- (3-Cyano-4-Hydroxyphenyl) -4-Methyl-1, 3-Thiazole-5-Carboxylate?
Ethyl 2- (3 - Cyano - 4 - Hydroxyphenyl) -4 - Methyl - 1,3 - Thiazole - 5 - Carboxylate, which is an organic compound. Its chemical structure is as follows:
Its core structure is a thiazole ring, which consists of a sulfur atom, a nitrogen atom and three carbon atoms to form a five-membered heterocyclic ring system. At position 2 of the thiazole ring, there is a substituted phenyl group, and at position 3 of the phenyl group, there is a cyano group (-CN), and at position 4, there is a hydroxyl group (-OH). At position 4 of the thiazole ring, there is a methyl group (-CH 🥰) connected. The 5th position of the thiazole ring is connected to a carboxylic acid ethyl ester group (-COOCH 2O CH < unk >). In this compound, each atom is connected to each other by covalent bonds to form a specific spatial configuration. Among them, carbon, nitrogen, oxygen, sulfur and other atoms combine with other atoms in different valence states to build a stable chemical structure. Overall, this structure endows the compound with unique physical and chemical properties and potential chemical reactivity, which may have important application value in organic synthesis, pharmaceutical chemistry and other fields.
What are the main uses of Ethyl 2- (3-Cyano-4-Hydroxyphenyl) -4-Methyl-1, 3-Thiazole-5-Carboxylate?
Ethyl 2- (3-Cyano-4-Hydroxyphenyl) -4-Methyl-1,3-Thiazole-5-Carboxylate (2- (3-cyano-4-hydroxyphenyl) -4-methyl-1,3-thiazole-5-carboxylic acid ethyl ester) is widely used in the field of medicine, and can be used as a key intermediate to help develop many drugs. Because of the specific group combination in its structure, it can interact with specific targets in organisms. In the process of anti-cancer drug research and development, or by modifying the structure of the compound, it can precisely act on specific proteins or signaling pathways of cancer cells, thereby inhibiting the growth and spread of cancer cells. In the field of pesticides, with its unique chemical properties, it may have certain bactericidal and insecticidal activities. After rational design and transformation, high-efficiency, low-toxicity and environmentally friendly pesticides can be developed, which is of great significance to the control of crop diseases and pests, and can ensure crop yield and quality. In the field of material science, due to the presence of special functional groups, it may participate in material synthesis and modification. For example, in the preparation of polymer materials, the polymer structure is introduced as a functional monomer, giving the material special properties such as fluorescence and adsorption, opening up new paths for the research and development of new functional materials. In short, Ethyl 2- (3-Cyano-4-Hydroxyphenyl) -4-Methyl-1, 3-Thiazole-5-Carboxylate has important potential application value in many fields, providing strong support for innovation and development in various fields.
What are the synthesis methods of Ethyl 2- (3-Cyano-4-Hydroxyphenyl) -4-Methyl-1, 3-Thiazole-5-Carboxylate?
Ethyl 2- (3 - Cyano - 4 - Hydroxyphenyl) -4 - Methyl - 1,3 - Thiazole - 5 - Carboxylate is an organic compound, and its synthesis methods are rich and diverse. The following are several common methods, just like the ancient alchemists' exploration of wonderful methods, all of which require careful and rigorous operation.
First, the aromatic compound containing cyanide and hydroxyl groups is used as the starting material. First, this raw material is mixed with specific sulfur-containing reagents and methylating reagents in a suitable solvent, such as in a quiet alchemy furnace, so that the various raw materials can be mixed with each other. The reaction system requires precise control of temperature and pH, just like the delicate control of heat during alchemy. Under mild heating and moderate alkali catalysis, sulfur atoms are ingeniously embedded to form the key structure of the thiazole ring, which is like gradually condensing a magical thing in a furnace. Subsequently, the ethyl ester group is introduced through the esterification reaction. This step requires the right esterification reagent and catalyst to successfully synthesize the target product.
Second, a specific thiazole derivative can be used. The benzene ring of the derivative is modified. The cyanide group is introduced at a specific position of the benzene ring first, and the cyanide reagent can be used to precisely control the reaction check point. After that, under suitable conditions, the hydroxyl group is introduced at another position of the benzene ring. This process requires fine adjustment of the reaction conditions to ensure the accurate connection of the hydroxyl groups. Finally, through subsequent reactions, the entire molecular structure is perfected to achieve the synthesis of Ethyl 2- (3 - Cyano - 4 - Hydroxyphenyl) -4 - Methyl - 1,3 - Thiazole - 5 - Carboxylate, which is like going through multiple processes and carefully carving out a delicate thing.
Furthermore, a multi-step series reaction can also be considered. The reaction process is cleverly designed, so that the raw materials in the same reaction system can undergo multiple steps in sequence, without cumbersome intermediate separation. Step by step, like a cleverly arranged chain, the complex structure of the target product is directly constructed. Although this method is ingenious, it requires extremely high compatibility of reaction conditions and reactions in each step, and requires careful layout by wise men to succeed.
What are the physicochemical properties of Ethyl 2- (3-Cyano-4-Hydroxyphenyl) -4-Methyl-1, 3-Thiazole-5-Carboxylate?
Ethyl 2- (3 - Cyano - 4 - Hydroxyphenyl) -4 - Methyl - 1,3 - Thiazole - 5 - Carboxylate is an organic compound. Its physical and chemical properties are unique and worth studying.
When it comes to physical properties, the appearance of this product is often in a specific form, either crystalline or powdery, depending on the preparation method and the environment. Its color is either colorless and transparent, or with a slight hue, due to impurities and molecular structure. Melting point is also an important physical property, which is the critical temperature at which a substance changes from solid to liquid. For this compound, the melting point reflects the strength of the intermolecular force. If the force is strong, the melting point is high, and vice versa. Knowing the melting point is crucial for the purification and identification of this compound.
As for the chemical properties, because its structure contains specific functional groups, the chemical activity is significant. Cyanide (-CN) has high reactivity and can participate in a variety of reactions, such as hydrolysis. Under certain conditions, cyanide can be converted into carboxyl groups. This reaction is often used in organic synthesis to construct new compounds. Hydroxy (-OH) is also an active functional group, which can participate in esterification reactions and react with acids to form ester compounds. In addition, the 1,3-thiazole ring is structurally stable but can also react under special conditions, adding a variety of reaction possibilities to the compound. Its ester group can be hydrolyzed under basic or acidic conditions, and the basic hydrolysis is more thorough, resulting in corresponding carboxylic salts and alcohols.
Ethyl 2- (3-Cyano-4-Hydroxyphenyl) -4-Methyl-1,3-Thiazole-5-Carboxylate The physicochemical properties are closely related to its structure and are of great significance in the fields of organic synthesis and drug development.
What is the price range of Ethyl 2- (3-Cyano-4-Hydroxyphenyl) -4-Methyl-1, 3-Thiazole-5-Carboxylate in the market?
I don't know the price range of "Ethyl 2- (3-Cyano-4-Hydroxyphenyl) -4-Methyl-1, 3-Thiazole-5-Carboxylate" in the market. This compound may be a special product used in professional chemical and pharmaceutical research and development, and its price often varies due to many factors such as purity, mass production scale, market supply and demand.
If it is high purity, scientific research grade, and the preparation process is complicated and the demand is limited, its price may be high; if the mass production scale is large and widely used, the price may be relatively easy. However, if you want to know the exact price range, you need to consult chemical raw material suppliers, reagent sellers, or professional chemical product trading platforms. Or communicate with industry insiders at relevant academic and industry conferences to get more accurate price information. It is unfortunate that I have not personally involved in market transactions, so it is difficult to give a clear answer to the price range.