Ethyl 2-(2-aminothiazole-4-yl)-2-methoxyiminoacetate

Ethyl-2 - (2-aminothiazole-4-yl) -2-methoxy iminoacetate, which is a crucial chemical substance in the field of organic synthesis. It has a wide range of uses, especially in the synthesis of medicines and pesticides, and plays a pivotal role.
In the field of pharmaceutical synthesis, this compound is often used as a key intermediate for the preparation of antibacterial and antiviral drugs. For example, when developing drugs for specific bacterial infections, with its unique molecular structure, it can precisely bind to specific targets in the body of the bacteria, so as to achieve the purpose of inhibiting the growth and reproduction of the bacteria, and then effectively treat related diseases. Due to the ingenious combination of aminothiazole and methoxyimino in its structure, it gives it special biological activity, making it very popular in drug development.
In the field of pesticide synthesis, ethyl-2 - (2-aminothiazole-4-yl) -2 -methoxyiminoacetate also plays a key role. It can be used as an important raw material for the synthesis of new and efficient pesticides, and the synthesized pesticides have shown excellent control effects on a variety of crop pests. This compound can interfere with the physiological and metabolic processes of pests, or damage their nervous system, so that pests cannot survive and multiply normally, ensure the healthy growth of crops, and improve the yield and quality of agricultural products.
In conclusion, ethyl-2 - (2-aminothiazole-4-yl) -2 -methoxyiminoacetate is used in the field of pharmaceutical and pesticide synthesis. With its unique structure and excellent properties, it has an extremely important position and makes great contributions to human health and agricultural production.

There are several methods for synthesizing 2 - (2-aminothiazole-4-yl) -2 -methoxyiminoacetate ethyl ester. One method is to first react 2-aminothiazole with ethyl chloroacetate to obtain 2 - (2-aminothiazole-4-yl) acetate. This step requires mild reaction conditions to avoid damage to the thiazole ring. Afterwards, the resulting product is reacted with methoxyamine hydrochloride in an alkaline environment, such as potassium carbonate. This is a key step. Precise temperature control and reaction time are required to promote the introduction of methoxyiminoacetate and finally obtain the target product. < Br >
Another method is to first react thiourea with ethyl bromopyruvate to form 2-aminothiazole-4-ethyl carboxylate through cyclization, and then carry out methoxyiminylation. Among them, the cyclization reaction requires a suitable solvent and catalyst. When methoxyiminylation, the amount of methoxyamine and the reactivity also need to be carefully considered to obtain the ideal yield.
Furthermore, the corresponding oxime can be prepared from 2-aminothiazole-4-formaldehyde, and then reacted with ethyl haloacetate. In this process, the preparation of oxime requires attention to the reaction conditions to ensure its purity and configuration. The selection and reactivity of halogenated ethyl acetate are also related to the formation of the product. Each method has its advantages and disadvantages. When synthesizing, according to actual needs, consider the availability of raw materials, the difficulty of reaction conditions, and the yield of various factors, and choose the most suitable method.

Ethyl 2- (2-aminothiazole-4-yl) -2-methoxyiminoacetate is an organic compound, and its physical and chemical properties are quite critical. This substance is mostly solid at room temperature, but the specific properties will also be affected by impurities and preparation processes.
Looking at its melting point, under specific conditions, the melting point is within a certain range. This property is very useful in identifying and purifying the substance. By measuring the melting point, its purity can be judged. In addition, its solubility is also an important property. It has a certain solubility in organic solvents such as ethanol and acetone, but its solubility in water is relatively limited. This difference in solubility provides a theoretical basis for the separation and extraction of the substance. In practice, the solvent can be selected according to its solubility.
In terms of chemical properties, the compound contains various functional groups such as amino groups, thiazole rings, methoxyimino groups and ester groups. The amino group is basic and can react with acids to form corresponding salts. The thiazole ring gives it certain stability and special reactivity, and can be used as a reaction check point in some organic synthesis reactions. Methoxyimino groups and ester groups also have reaction characteristics. The ester group can undergo hydrolysis reaction. Under acidic or basic conditions, the hydrolysis rate is different from the product. Under basic conditions, the hydrolysis is relatively complete, resulting in corresponding carboxylate and alcohol; under acidic conditions, the hydrolysis is reversible.
In addition, Ethyl 2- (2-aminothiazole -4-yl) interacts -2-methoxyiminoacetate functional groups within the molecule, resulting in more complex and diverse chemical properties. Understanding these physicochemical properties is of great significance for their applications in organic synthesis, drug development and other fields, and can help researchers rationally design reaction paths to improve product yield and purity.

What you are asking is the price range of ethyl 2- (2-aminothiazole-4-yl) -2-methoxyiminoacetate in the market. However, the price of this product often varies due to various reasons, and it is difficult to determine a certain number.
First, its price is related to the cost of production. To prepare this compound, the purchase price of raw materials, the energy consumption in the production process, and the loss and maintenance of equipment are all cost factors. If raw materials are scarce or expensive, the price of energy required for production fluctuates, or the equipment needs to be maintained at a high cost, the cost will increase, which will affect the selling price.
Second, the supply and demand situation of the market is also key. If there is a strong demand for this product in many industries, but the supply is limited, such as the pharmaceutical industry using it as an important intermediate, the demand will increase sharply, and the price will rise. On the contrary, if the supply exceeds the demand, the manufacturer may reduce the price in order to sell its goods.
Third, the quality of the product also affects the price. High-quality products, due to the finer preparation process and fewer impurities, have better effects in specific application scenarios, and their price is often higher than that of ordinary quality products.
Fourth, regional differences also make the price different. Different places have different tax policies, transportation costs, and market competition. For example, in economically developed areas, the demand is large and the logistics is convenient, and the price may be relatively stable; in remote areas, the price may be slightly higher due to high transportation costs.
To sum up, the price of ethyl 2- (2-aminothiazole-4-yl) -2-methoxyiminoacetate may fluctuate between tens of yuan and hundreds of yuan per kilogram. The specific price is difficult to determine and must be carefully reviewed according to the current market conditions.

Ethyl 2- (2-aminothiazole-4-yl) -2-methoxyiminoacetate, that is 2- (2-aminothiazole-4-yl) -2-methoxy iminoacetate ethyl ester, this substance is widely used in the field of pharmaceutical synthesis, especially in the synthesis of cephalosporins antibiotics. As for the manufacturers, in the land of China, it is like a star list, which is difficult to describe, but there are several famous ones.
The first one is Zhejiang Haixiang Pharmaceutical joint stock company. This company has a long reputation for the research and development, production and sales of characteristic raw materials and pharmaceutical intermediates. In the field of fine chemicals, it produces Ethyl 2- (2-aminothiazole-4-yl) -2-methoxyiminoacetate with profound heritage and exquisite skills, which is of high quality and is favored by many pharmaceutical companies in the industry.
Furthermore, Jiangsu Yangnong Chemical Group Co., Ltd. cannot be ignored. The group has dabbled in the fields of pesticides, chlor-alkali, and fine chemicals, and has deep attainments. With advanced equipment and strict quality control system, its Ethyl 2- (2-aminothiazole-4-yl) -2-methoxyiminoacetate is not only sold well in China, but also sold overseas, and has won praise from all over the world.
Another Shandong Xinhua Pharmaceutical joint stock company, as an important chemical synthesis pharmaceutical enterprise in China, also has a layout for the production of Ethyl 2- (2-aminothiazole-4-yl) -2-methoxyiminoacetate. With years of pharmaceutical experience and technical precipitation, its product quality is stable and it has a place in the market.
These are all leaders in the production of Ethyl 2- (2-aminothiazole-4-yl) -2-methoxyiminoacetate, but the chemical industry is vast, and similar manufacturers are diverse, each with its own strengths, and it is difficult to list them one by one.