Ethyl 1 3 Thiazole 4 Carboxylate
quinoline thiophene imidazole thiazole

Ethyl 1,3-thiazole-4-carboxylate

    Specifications

    HS Code

    698114

    Chemical Formula C6H7NO2S
    Molar Mass 157.19 g/mol
    Appearance Typically a solid or liquid (state may vary depending on conditions)
    Boiling Point Data may vary, but generally in a specific range depending on purity
    Melting Point Specific melting point value (varies with purity)
    Solubility In Water Limited solubility
    Solubility In Organic Solvents Soluble in certain organic solvents like ethanol, dichloromethane
    Density A specific density value (in g/cm³, varies with purity and temperature)
    Flash Point Flash point value relevant for fire - hazard assessment
    Pka No data found (if applicable for acidic or basic properties)
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading Ethyl 1,3-thiazole-4-carboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of Ethyl 3-thiazole-4-carboxylate?
    Ethyl 1,3-thiazole-4-carboxylate is an organic compound with a thiazole ring and an ethyl carboxylate group. The thiazole ring consists of a sulfur atom and a nitrogen atom to form a five-membered heterocycle. This five-membered ring is aromatic and gives the compound unique chemical properties.
    Structurally, the 1st and 3rd positions of the thiazole ring are specific atomic connection check points. In this compound, the 4th position is connected to the ethyl carboxylate group. In the ethyl carboxylate group, the carboxyl group (-COOH) is esterified with ethanol (C 2O H OH) to form an ester bond (-COO-), that is, -COOC 2O H structure.
    This structure endows Ethyl 1,3-thiazole-4-carboxylate with specific physical and chemical properties. Due to its ester group, it can undergo hydrolysis, alcoholysis and other reactions; the existence of thiazole ring makes it have specific reactivity and application in the field of organic synthesis, or can be used to prepare biologically active compounds, and may have potential uses in pharmaceutical chemistry, pesticide chemistry and other fields.
    What are the main uses of Ethyl 3-thiazole-4-carboxylate
    Ethyl-1,3-thiazole-4-carboxylic acid esters are an important category of organic compounds and have their uses in various fields.
    In the field of medicinal chemistry, they are often the key intermediates for the creation of new drugs. Due to their unique chemical structure, they can interact with specific targets in organisms to help develop drugs with specific curative effects. For example, in the synthesis of some antibacterial and anti-inflammatory drugs, ethyl-1,3-thiazole-4-carboxylic acid esters play an indispensable role. Through ingenious chemical reactions, they are integrated into the molecular structure of drugs to endow drugs with excellent biological activity and pharmacological properties.
    In materials science, it also has outstanding performance. It can be used as a raw material for the preparation of special functional materials. After specific processing, the materials may have unique optical and electrical properties. For example, in the synthesis of some optoelectronic materials, the introduction of this compound can optimize the key indicators such as the luminous efficiency and stability of the material, and contribute to the development of new display technologies and optoelectronic devices.
    Furthermore, in the field of pesticides, ethyl-1,3-thiazole-4-carboxylate also shows potential value. After rational design and transformation, high-efficiency and low-toxicity pesticide products can be derived, which are quite effective in the control of crop diseases and pests. Its structural characteristics help to precisely act on the physiological processes of pests, and reduce the adverse impact on the environment while ensuring agricultural production.
    Overall, ethyl-1,3-thiazole-4-carboxylic acid ester has a wide range of important applications in many fields such as medicine, materials, and pesticides due to its unique chemical structure, providing a solid chemical foundation and innovative possibilities for the development of related fields.
    What are the synthesis methods of Ethyl 1, 3-thiazole-4-carboxylate
    The method of preparing ethyl 1,3-thiazole-4-carboxylic acid ester has been known for a long time. One of the common ways is to use thiazole compounds as starting materials. First take the appropriate thiazole and make it react with the carboxyl group-containing reagent under specific conditions. For example, use thiazole and carboxylation reagent in a suitable solvent, or with a catalyst, through heating, stirring and other operations, so that the substitution reaction occurs, so that the carboxyl group is connected to the 4-position of thiazole, and then esterified with ethanol, ethyl 1,3-thiazole-4-carboxylic acid ester can be prepared. When esterification, acid may be required as a catalyst to control the temperature and reaction time to promote the smooth progress of the reaction. < Br >
    Second, we can start from the construction of thiazole ring. Compounds containing sulfur and nitrogen atoms and ester derivatives containing carboxyl groups are selected to undergo cyclization reaction in an appropriate reaction system. In this process, by adjusting the ratio of reactants, reaction temperature, reaction time and other conditions, the reaction is promoted towards the direction of generating the target product. The reaction environment may be protected by inert gas to avoid side reactions. After this cyclization reaction, ethyl 1,3-thiazole-4-carboxylic acid esters are directly generated.
    Furthermore, other compounds with similar structures are also used as the starting point and converted through multi-step reactions. First, the starting material is modified with functional groups, and the required atoms and groups are gradually introduced. Finally, ethyl 1,3-thiazole-4-carboxylic acid ester is formed through key steps. This approach requires fine control of each step of the reaction to ensure reaction selectivity and yield. Each method has its own advantages and disadvantages, and it is necessary to choose an appropriate method to prepare it according to the actual situation, such as the availability of raw materials, cost, and difficulty of reaction conditions.
    What are the physical properties of Ethyl 3-thiazole-4-carboxylate?
    Ethyl 1,3-thiazole-4-carboxylate is an organic compound with specific physical properties. It is a colorless to light yellow liquid. This color state is easy to observe and distinguish. In experimental and industrial applications, the color and state can be used as a preliminary judgment basis.
    This substance is volatile to a certain extent. In an open environment, molecules can easily escape from the liquid phase and enter the gas phase. Due to its properties, it is necessary to pay attention to the ventilation of the operating environment when using it to avoid safety hazards caused by the accumulation of high-concentration steam.
    Ethyl 1,3-thiazole-4-carboxylate has a specific melting point and boiling point. The melting point is [specific melting point value], and the boiling point is [specific boiling point value]. The melting point determines the temperature of a substance from solid to liquid, and the boiling point is the temperature of liquid to gaseous. Knowing these two parameters is of great significance for its separation, purification and control of reaction conditions. For example, when distilling and purifying, the temperature is set according to the boiling point to separate the substance from other impurities.
    Its density is [specific density value], and the density reflects the unit volume mass. In the study of solution preparation and mixing system, the density data can help determine the proportion and dosage of each component.
    In addition, Ethyl 1,3-thiazole-4-carboxylate has unique solubility and is soluble in some organic solvents, such as ethanol, ether, etc., and is difficult to dissolve in water. This solubility determines its dispersion and reaction behavior in different solvent systems, and the selection of a suitable solvent is crucial for its chemical reaction and application.
    What is the market outlook for Ethyl 1, 3-thiazole-4-carboxylate?
    Ethyl 1,3-thiazole-4-carboxylate (ethyl 1,3-thiazole-4-carboxylate) is an important chemical raw material in the field of organic synthesis. Looking at its market prospects, it covers the following numbers.
    In the field of medicine and chemical industry, this compound has great potential value. Many drug development relies on organic synthesis intermediates. Ethyl 1,3-thiazole-4-carboxylate may provide a key framework for the creation of new drugs due to its unique chemical structure. Nowadays, pharmaceutical research and development has a growing demand for novel and efficient synthetic blocks, so it may welcome broad market opportunities in this field. Many pharmaceutical companies and scientific research institutions are actively exploring new therapeutic drugs. This compound may become a hot target for research and development, which is expected to give rise to a series of drugs with unique therapeutic effects, and the market demand may grow as a result.
    In the field of pesticide chemistry, 1,3-thiazole-4-carboxylate ethyl ester also has application potential. With the development of agricultural modernization, the demand for high-efficiency, low-toxicity and environmentally friendly pesticides is increasing. The compound may be chemically modified to derive new pesticide ingredients to meet this demand. If high-efficiency pesticide products can be developed based on this, it will surely be able to occupy a certain market share.
    However, its market prospects are not without challenges. The competition in the field of chemical synthesis is intense, and many similar intermediates are also competing for the market. To make ethyl 1,3-thiazole-4-carboxylate stand out, it is necessary to continuously optimize the synthesis process, reduce production costs, and improve product quality and competitiveness. And chemical production has strict environmental protection requirements, and the production process needs to ensure compliance with environmental regulations, so as not to limit market expansion due to environmental protection issues.
    Overall, the Ethyl 1,3-thiazole-4-carboxylate market has promising prospects, but it also needs to deal with challenges such as competition and environmental protection. If it can be properly handled, it will be able to gain a place in the chemical-related market.