ethyl 1,3-benzothiazole-2-carboxylate

Ethyl 1,3-benzothiazole-2-carboxylate, Chinese name ethyl 1,3-benzothiazole-2-carboxylate, this substance is widely used. In the field of medicinal chemistry, it is often a key intermediate for the creation of new drugs. Due to its unique molecular structure, it endows drugs with specific biological activities and pharmacological properties. For example, when developing antibacterial drugs, new compounds with high antibacterial activity and low toxicity can be obtained through their structural modification, providing a new way to treat infectious diseases.
In the field of materials science, it can participate in the synthesis of functional materials. For example, the preparation of materials with special optical and electrical properties shows potential application value in organic Light Emitting Diode (OLED), sensors and other fields. Due to its own structural characteristics, the photoelectric properties of the material can be regulated, and the performance and stability of related devices can be improved.
In the field of agriculture, it can also be used as a raw material for synthesizing new pesticides. After rational structural design and modification, high-efficiency, low-toxicity and environmentally friendly pesticides have been created, which can help control crop diseases and insect pests and ensure the safety and sustainable development of agricultural production.
In summary, ethyl 1,3 - benzothiazole - 2 - carboxylate has important uses in medicine, materials, agriculture and other fields, and contributes key forces to promoting technological development and innovation in various fields.

The method of synthesizing ethyl 1,3-benzothiazole-2-carboxylate has been around for a long time. The common one is to use 2-aminobenzenethiol and ethyl bromoacetate as raw materials. The two are combined and condensed to form this target. During the reaction, an appropriate base is used as a catalyst, such as potassium carbonate, in an organic solvent, often acetonitrile as a solvent, heated and refluxed.
There is also a method of starting with 2-mercaptobenzimidazole. It is first combined with halogenated ethyl acetate. Halogenated, such as brominated or chlorinated ethyl acetate, can be used. This reaction also needs to be carried out in an alkaline environment, such as sodium hydroxide or potassium hydroxide alcohol solution, through nucleophilic substitution reaction to obtain ethyl 1,3-benzothiazole-2-carboxylate.
Or use o-aminothiophenol and ethyl chloroformate as raw materials. Under suitable conditions, such as in the presence of an organic base such as pyridine, the reaction occurs, and the intermediate product is formed. Then it is cyclized in the molecule to obtain the target ethyl 1,3-benzothiazole-2-carboxylate.
All methods have advantages and disadvantages. The method using 2-aminobenzenethiol and ethyl bromoacetate as raw materials, the raw materials are relatively easy to obtain, but the reaction conditions need to be carefully regulated; the method using 2-mercaptobenzimidazole as the starting material, the steps are relatively simple, but the price of the starting material may be different; the method using o-aminothiophenol and ethyl chloroformate as raw materials, the reaction mechanism is clear, but the side reactions may need attention. When synthesizing, choose the best according to the actual situation, such as the availability of raw materials, cost, yield and other factors.

Ethyl-1,3-benzothiazole-2-carboxylic acid ester, this is an organic compound. Looking at its physical properties, it is mostly solid under normal conditions, with a white or off-white crystalline powder and a certain melting point. Its melting point is about 90-92 ° C. With this characteristic, it is quite useful in identification and purity determination.
When it comes to solubility, it shows different solubility in organic solvents. It can be well dissolved in common organic solvents such as ethanol and acetone, because ethyl-1,3-benzothiazole-2-carboxylic acid ester molecules can form suitable interactions with such organic solvent molecules, such as van der Waals force, hydrogen bonds, etc. However, the solubility in water is not good, because the proportion of hydrophobic groups in the molecule is large, and it is difficult to form an effective interaction with water molecules, which makes it difficult to disperse and dissolve in water.
Ethyl-1,3-benzothiazole-2-carboxylate also has a specific odor and emits a weak aromatic odor, which is related to the benzene ring and heterocyclic part of its molecular structure, which endow it with certain volatility and odor characteristics. At the same time, the density of this substance is relatively large. When mixed with other substances or participating in the reaction, this density characteristic may affect the phase distribution and mass transfer process of the reaction system. In addition, its stability is also worthy of attention. Under normal conditions, if properly preserved, its properties are relatively stable; but under extreme conditions such as high temperature, strong acid and alkali, the molecular structure may change, causing chemical properties to change.

Now you ask what the market price of "ethyl 1,3 - benzothiazole - 2 - carboxylate" is. This substance is an organic compound, and its market price often varies for various reasons.
First, whether the purity of quality is the main reason. If the quality is pure and excellent, the price will be high; if it is miscellaneous, the price will drop. Like a good tool of ancient times, the price of refined manufacturers is high, and the price of crude manufacturers is low.
Second, the situation of demand and supply is also serious. If there are many people who want it, the price will rise; if the supply exceeds the demand, the price will fall. Just like the goods in the city, if you need more, you will be expensive, and if you accumulate more, you will be cheap.
Third, the difficulty of making and the cost of materials are both involved. If the production is complex and the materials are expensive, the cost will be high and the price will be high; if the production is easy and the materials are cheap, the price will be low. It is still a palace to build, but the materials are expensive and complex, and the materials are cheap and simple, and the cost will be saved.
However, I do not know the current "ethyl 1,3 - benzothiazole - 2 - carboxylate". You can ask the commercial store of chemical reagents, the market of chemical raw materials, or find it on the online platform of chemical trading, and you can know its recent price.

Ethyl-1,3-benzothiazole-2-carboxylic acid ester is a kind of organic compound. Its storage conditions are the most critical, which is related to the stability and quality of this material.
In the context of the analogy of "Tiangong Kaiwu", the storage of the material should be observed and the appropriate method should be followed. Ethyl-1,3-benzothiazole-2-carboxylic acid ester should be stored in a cool, dry and well-ventilated place. If it is cool, avoid the disturbance of high temperature. High temperature can easily cause its molecules to be active, or trigger chemical reactions, causing it to deteriorate. This is like storing grain in summer, and high temperature is prone to mildew.
Dry environment is also indispensable. Moisture easily interacts with compounds, or causes them to hydrolyze, damaging their structure and properties. Looking back at the past, storing salt in a damp place would easily dissolve water, which is the harm of water.
Well-ventilated, it can make the air flow smoothly and disperse the volatile gas that may accumulate. If stored in a closed place with no gas circulation, the volatile gas will accumulate but not disperse, or increase the risk of ignition and explosion, and affect the purity of the compound.
Furthermore, this substance should be kept away from fire, heat sources and oxidants. Fire and heat sources can cause it to burn, and oxidants can meet or react violently. This is like the ancients using fire, and a little carelessness can cause a prairie fire, and heterogeneous contact, often unexpected.
When storing, it should be contained in a sealed container to ensure that it is isolated from the outside world and free from air and water vapor. All of these are the important ways to properly store ethyl-1,3-benzothiazole-2-carboxylate to protect its quality and extend its use.