Chemical Name | 5-(2-chlorophenyl)-1,3-thiazole-2(3H)-thione |
Common Name | Clomethiazole |
Form | Can be in forms like capsules, oral solutions, injection |
Mechanism Of Action | Enhances GABA - mediated neurotransmission |
Uses | Treatment of alcohol withdrawal, insomnia, seizure control |
Side Effects | Drowsiness, dizziness, hypotension, respiratory depression |
Pharmacokinetics Absorption | Rapidly absorbed from the gastrointestinal tract |
Pharmacokinetics Distribution | Widely distributed in the body including the brain |
Pharmacokinetics Metabolism | Metabolized in the liver |
What are the main benefits of Clomethiazole?
Clomethiazole (Clomethiazole), its function in the medical way, is quite specific. The effect of this drug on various diseases can be discussed from several points of view.
First, in the case of insomnia, Clomethiazole can calm the mind and help sleep and sleep. When people can't sleep, they are often disturbed by restlessness, and this drug is like a wave of tranquility, which can calm the mind and gradually fall asleep. It can regulate neurotransmitters in the brain, slow down the activity of excited nerves, and create a tranquil environment to promote sleep.
Second, for alcohol withdrawal syndrome, Clomethiazole has a good effect. People who are addicted to alcohol often experience discomfort when they suddenly stop drinking, such as tremor, delirium, etc. Clomethiazole can relieve these symptoms and help patients get through the withdrawal period smoothly. Because it can act on the nervous system, correct the neurological dysfunction caused by alcohol, and return the nerve conduction in the body to normal.
Third, in the field of epilepsy treatment, clomethiazole also has a place. The onset of epilepsy is caused by abnormal discharge of nerve cells in the brain. Clomethiazole can stabilize the membrane potential of nerve cells and inhibit the spread of abnormal discharge, thereby reducing the frequency and degree of seizures.
However, the use of drugs requires caution. Although clomethiazole has the above effects, it is also advisable to avoid it. Medicators should follow the doctor's advice and use it according to their own condition and constitution. They should not change the dose without authorization to avoid other changes.
What are the common side effects of Clomethiazole?
Clomethiazole (Clomethiazole) is a drug, but it often has various adverse reactions.
The first to bear the brunt is the impact of the central nervous system. After taking this drug, people often appear drowsy, as if sleepy, difficult to self-control, and feel tired when doing things. It is difficult to gather energy and slow thinking. If people are in a drowsy state, they lose their agility in words and deeds. And vertigo is not uncommon. When standing or walking, they feel the world is spinning, and their balance is difficult to hold. It is easy to cause the risk of falling, and it is dangerous.
Furthermore, it is also harmful to the gastrointestinal tract. The symptoms of nausea and vomiting are quite common, and the abdomen seems to have a feeling of overturning the river. The stomach qi is reversed, and it is difficult to vomit. The diet is also tired, the appetite is greatly reduced, and the food is not interesting. What's more, it may cause diarrhea, intestinal peristalsis is abnormal, and frequent toilet use is uneasy.
In addition, some people can cause changes in the blood system after taking medication. The number of white blood cells or platelets is reduced, and the body's defense and coagulation functions are damaged. If there are few white blood cells, the power to resist external evil is weak, and it is easy to contract various diseases; if there are few platelets, there will be slight damage, bleeding is difficult to stop, and petechiae and petechiae may also appear on the skin.
And long-term or large-scale use of this medicine, there is still a worry of withdrawal reaction. Once the drug is stopped, the body can tremor, anxiety, insomnia, etc., as if the body is suffering from a serious disease, and the pain is unbearable. This is a common adverse reaction of clomethiazole, and drug users should pay careful attention to prevent accidents.
How is Clomethiazole used?
"Tiangong Kaiwu" was written by Song Yingxing in the Ming Dynasty. It describes many crafts and technologies in ancient classical Chinese, but the book does not involve "Clomethiazole". Today, this medicine is described in the form of ancient classical Chinese.
For the husband of Clomethiazole, the medicine made by Xitu is also used, and its use is often related to the treatment of convulsions and tremors. For delirium tremens in acute alcohol withdrawal, the usage is as follows: Start with a certain amount, such as adults often use a certain volume of liquid medicine, and infusion through the vein at an appropriate rate to relieve their mania and tremor. Later, as the symptoms change, the amount should be reduced to maintain it, but the rate and amount should be based on the judgment of the doctor.
If it is used for the treatment of epilepsy, the usage of children and adults is different. Children should be given an appropriate amount of medicine, either orally or through other channels, according to their weight, and with their growth and symptoms, the doctor should adjust the dose. Adults should also take tablets or other drugs orally according to the frequency and degree of seizures, and they should be taken regularly. There should be no omissions to prevent the recurrence of epilepsy.
In short, this medicine must be used in accordance with the doctor's instructions, observe its symptoms, measure its severity, and then use it in an appropriate way to obtain its effect and avoid its harm. During medication, it is also necessary to check the body's response frequently. If there is any discomfort, please inform the doctor immediately to find a good plan.
In which diseases is Clomethiazole used?
Clomethiazole is also a medicine, which is widely used in various diseases. Gu Yun: "The treatment of diseases is more expensive than medicine." This medicine is effective in the treatment of epilepsy. The disease of epilepsy, when it occurs, is stunned and convulses, and it looks like a god. Clomethiazole can calm its shock, stop its convulsion, and slow down the trend of epilepsy. "Nei Jing" says: "All kinds of violence and strength belong to the wind." The hair of epilepsy is caused by wind and phlegm. This medicine may calm the wind and reduce phlegm, and calm the brain and calm epilepsy.
In the disease of tremor, it is also useful. For tremors, the limbs tremble involuntarily, which is very disturbing. Clomethiazole can adjust its tendons and veins, and slow down its tremor. " "The Criteria for Treatment" goes: "Tremor, shaking; vibration, movement. The tendons and veins cannot be restrained and cannot be held, and the wind is like a sign." This medicine may remove the wind and relieve the tendons, so that the tremor is reduced.
Furthermore, in alcohol withdrawal syndrome, Clomethiazole is also a good agent. If a person is addicted to alcohol for a long time, he will quit it suddenly, and various diseases will rise up, such as delirium tremor, restlessness, etc. This medicine can relieve its discomfort and help people who have quit drinking get through the time of withdrawal smoothly. For example, the "Compendium of Materia Medica" says that the effect of medicine should be observed and its nature should be taken into account. Clomethiazole can regulate qi and blood, calm the mind and mind, and make the road to quitting alcohol less twists and turns.
In summary, for diseases such as epilepsy, tremor, and alcohol withdrawal syndrome, Clomethiazole can be used to help people recover from the pain of the disease.
What are the precautions when using Clomethiazole?
In the case of flumethiazole, when taking medicine, many matters must not be ignored.
The first thing to pay attention to is its applicable symptoms. This medicine is mostly used for delirium tremens due to alcohol withdrawal, and can also treat insomnia and other diseases. However, it must be used according to the doctor's advice, and it is indeed the corresponding disease. Only then can the medicine be applied, and it should not be used recklessly.
Furthermore, the control of the dose is crucial. The dosage of the medicine must be accurate. If it is too small, it will be difficult to achieve the curative effect, and if it is too much, it will be dangerous to cause poison and side effects. Doctors should make prudent decisions according to the patient's physical condition and the severity of the disease. People who use the medicine should not increase or decrease the dose without authorization to prevent accidents.
Also, when the course of There may be symptoms such as drowsiness, dizziness, ataxia, etc., which are all common adverse reactions. In case of such cases, please report to the doctor immediately in order to weigh the pros and cons and decide the treatment strategy. What's more, if you see signs of allergies, such as rash, itching, breathing difficulties, etc., you must immediately stop taking the medicine and treat it urgently.
There are other compatibility taboos, and they should not be ignored. When used in combination with other medicines, it may interact with each other, causing the effect of the medicine to become easier, or increasing the risk of adverse reactions. Therefore, when seeking medical treatment, be sure to inform the doctor in detail of the medicines used, so that they can be considered thoroughly and avoid conflicts.
Diet is also related to the way of medication. Alcohol consumption should be prohibited, because it may be in combination with the drug, aggravating the inhibition of the central nervous system, causing lethargy, respiratory depression and other crises.
As for the elderly, children, pregnant women and nursing mothers and other special groups, the use of medication should be especially cautious. The old viscera is gradually declining, the children's organs are incomplete, and pregnant women and nursing mothers are related to the health of two generations. The choice of medication must weigh the pros and cons and strive for safety.
In short, when using clomethiazole, careful attention should be paid to the application, dosage, reaction, compatibility, diet and special groups to ensure the safety and effectiveness of the medication.