Name | Clomethiazole HCl |
Chemical Formula | C7H8ClNOS·HCl |
Molecular Weight | 226.12 g/mol |
Appearance | White to off - white crystalline powder |
Odor | Characteristic |
Solubility | Soluble in water, ethanol |
Melting Point | 152 - 156 °C |
Pka | 3.94 |
Ph 1 Solution | 3.5 - 4.5 |
Storage Conditions | Store in a cool, dry place, protected from light |
What are the main benefits of Clomethiazole HCl?
Clomethiazole + HCl is a medicine. Its main effect is related to calming the mind and relieving spasms. This medicine is used in medicine, often to calm epileptic seizures and help patients avoid the pain of convulsions. The development of epilepsy, convulsions of mind, convulsions of limbs, patients cannot be disturbed. Clomethiazole + HCl into the body can regulate the transmission of neurotransmitters, so that the activity of nerve cells returns to normal track, and the trend of epilepsy is suppressed.
And in the case of tremor, this medicine is also effective. Such as the idiopathic tremor of the elderly, the limbs tremble involuntarily, and the daily movements are difficult. Clomethiazole + HCl can act on the junction between the nerves and muscles, relax the tension of the muscles, make the tremor gradually lighter, and help the patient regain the stability of the limbs.
In addition, for the discomfort of alcohol withdrawal, this medicine also helps. If people are addicted to alcohol for a long time, they suddenly quit, and they often experience irritability, tremors, hallucinations and other withdrawal symptoms. Clomethiazole + HCl can relieve such discomfort, help people who have recovered from alcohol to get through the difficult period smoothly, gradually get rid of the shackles of alcohol, and restore a healthy body.
What are the common side effects of Clomethiazole HCl?
The common side effects of Clomethiazole + HCl have various manifestations. Drowsiness and drowsiness are quite common. When this drug is introduced into the body, it is easy to disturb the mind, cause mental laziness, people often feel drowsy, it is difficult to concentrate on things, and the efficiency of daily activities is also reduced.
Dizziness is also common. After taking the drug, you may feel heavy and light, and your body is like a cloud. When walking, it is difficult to maintain your balance, unstable, and often accompanied by a feeling of dizziness, and your vision seems to be shaking, which is easy to cause the risk of falling.
Gastrointestinal discomfort is also common. There may be nausea and vomiting, the epigastric area is full and uncomfortable, the appetite is also reduced, and there is no interest in seeing delicious food. What's more, there may be vomiting, diarrhea, abnormal spleen and stomach transportation, and difficult to melt water and grains, affecting the body's nutrient intake.
The central nervous system may be affected. If there is ataxia, uncoordinated body movements, and it is difficult to reach out to fetch or move forward, it is as stable as usual. Speech or unclear, difficult to express the meaning, unsatisfactory words, hindering normal communication with people.
Respiratory depression cannot be ignored. The medicine is used in the respiratory center, or it can cause slow respiratory rate and deep reduction, which can be life-threatening in severe cases. In the elderly, frail and those with poor respiratory function, special vigilance is required.
Skin allergic reactions occasionally occur. Erythema and itching can be seen on the skin, and the erythema is even worse after scratching, and the itching is unbearable, which affects the comfort and quality of life of patients.
How is Clomethiazole HCl used?
In the case of Clomethiazole + HCl, it is a medicine. The method of use should be followed by a doctor's advice. This medicine is mostly used orally. In the treatment of alcohol withdrawal, a certain amount of dosage is often taken according to the time. At the beginning of use, the amount may be slightly larger, and then gradually decreased. For example, the first dose can be given several tablets, and then reduced according to the situation, several times a day, divided and taken.
As for the treatment of epilepsy, the dosage also varies depending on the patient's condition, age, body, etc. Children and adults have different dosages. During the course of medication, the doctor must carefully observe the patient's response, observe the change of the disease, and adjust the dosage and method of use.
In addition, those who take this medicine should avoid alcohol and other central inhibitory agents to prevent it from increasing its inhibitory effect and causing adverse reactions. And during the medication, if you feel uncomfortable, such as drowsiness, vomiting, rash, etc., please tell the doctor, and the doctor must take action. The way of medication cannot be changed without changing it, and you must follow the doctor's advice, so that the security can be complete and effective.
Who is Clomethiazole HCl suitable for?
Clomethiazole hydrochloride (Clomethiazole + HCl) is also a drug. It is suitable for all kinds of people, covering the following categories.
The first one is quite suitable for people with insomnia. "Nei Jing" says: "If the stomach is not in harmony, you will be restless." If people are restless and can't sleep at night due to various reasons, clomethiazole hydrochloride can help them calm their minds, promote sleep, improve the quality of sleep, and make them sleep peacefully.
The second one is beneficial to people with alcohol withdrawal syndrome. Alcohol is the essence of water valley, and its qi is strong. If people are addicted to alcohol and stop drinking, they often have all kinds of discomfort, such as tremors and delirium. This drug can slow down the symptoms caused by alcohol withdrawal and gradually calm the body.
Furthermore, it is also suitable for some epilepsy patients. Epileptics, or due to congenital insufficiency of endowments, or due to acquired emotional, traumatic and other disorders of the viscera, phlegm obsession, and epilepsy syndrome. Clomethiazole hydrochloride can calm the wind, reduce phlegm and open the orifice, and has a certain effect on the control of epilepsy, which can reduce the frequency and degree of seizures.
Those who use drugs must be cautious. It should be used in accordance with the doctor's advice, and the dosage should not be increased or decreased by yourself to avoid all kinds of changes.
Does Clomethiazole HCl interact with other medications?
Clomethiazole + HCl may interact with each other. This drug acts on the nervous system to achieve sedative, hypnotic, and anticonvulsant effects.
If used with central nervous depressant drugs, such as ethanol, barbiturates, and benzodiazepines, its inhibitory effect may increase. Ethanol can already inhibit the central nervous system. In combination with clomethiazole, it can cause respiratory depression, deep sedation, and even coma, which is dangerous. When barbiturates and benzodiazepines are also central depressants, when taken together, the degree of neurosuppression is exacerbated, and the patient may be overly sleepy, listless, and ataxia.
Furthermore, when used in combination with antihypertensive drugs, the effect of lowering blood pressure may be too great. Clomethiazole may affect the regulation mechanism of cardiovascular, and in coordination with antihypertensive drugs, blood pressure drops sharply, which can cause dizziness, fatigue, and even fainting, endangering life.
If taken with anticoagulants, it may change the function of coagulation. The dose of anticoagulants has been precisely regulated, and the intervention of clomethiazole, or breaking the balance of coagulation, may increase the risk of bleeding, such as subcutaneous ecchymosis, bleeding gums, nosebleeds, etc.
Therefore, when taking drugs, doctors must carefully review the drugs taken by patients, weigh the advantages and disadvantages, avoid the harm of interaction, and ensure the safety of patients taking drugs. Medications should also follow the doctor's advice and do not combine various medications to prevent unexpected changes.