Benzothiazole, 7-bromo-

7-Bromobenzothiazole is one of the organic compounds. Its physical properties are quite unique. Looking at its shape, at room temperature, it is mostly white to light yellow crystalline powder, which makes it easy to handle and weigh in many chemical operations and experiments.
When it comes to the melting point, it is about 78-82 ° C. The melting point characteristics are not only crucial for its identification, but also play an important role in the process of separation and purification. This temperature range allows chemists to accurately determine the purity and authenticity of the compound by means of melting point determination.
In addition to its solubility, 7-bromobenzothiazole is slightly soluble in water, but it exhibits good solubility in common organic solvents such as ethanol, dichloromethane, chloroform, etc. This solubility characteristic provides convenience for the selection of reaction solvents in the field of organic synthesis, making the reaction easier to occur and proceed. Good solubility in organic solvents is conducive to full contact and collision of reactant molecules, thereby improving reaction efficiency and yield. In addition, the density and stability of 7-bromobenzothiazole are also similar to many organic compounds. Under normal storage and use conditions, their properties are relatively stable, and they are not prone to spontaneous decomposition or other chemical reactions. This provides a solid foundation for their application in the chemical industry and scientific research.

7-Bromobenzothiazole is a family of organic compounds. It has unique chemical properties and is widely used in many fields.
Looking at its physical properties, it is mostly solid at room temperature, ranging in color from light yellow to white, and the form may be crystalline powder. Its melting point and boiling point depend on the intermolecular force, and it can be melted and boiled under specific conditions.
Chemically, the bromine atom in 7-bromobenzothiazole is quite active. This bromine atom participates in the nucleophilic substitution reaction. When encountering nucleophilic reagents, the bromine atom is easily replaced to form a new compound. For example, when reacted with amino-containing reagents, bromine can be replaced by amino groups to form nitrogen-containing derivatives, which is of great significance in the field of drug synthesis and often lays the foundation for the creation of new drugs.
Furthermore, the benzothiazole ring has aromatic properties, which endows the compound with certain stability, and can also participate in aromatic electrophilic substitution reactions. Under appropriate catalyst and reaction conditions, other functional groups can be introduced into the ring to expand its chemical structure diversity, which is crucial in the field of materials science and helps to develop materials with specific optical and electrical properties.
In terms of solubility, 7-bromobenzothiazole has acceptable solubility in common organic solvents such as dichloromethane and chloroform, but poor solubility in water. This characteristic needs to be taken into account when separating, purifying and selecting reaction solvents.
Due to its active chemical properties and unique structure, 7-bromobenzothiazole is a key intermediate in the pharmaceutical, pesticide, material and other industries, promoting technological innovation and Product Research & Development in many fields.

7-Bromobenzothiazole has a wide range of uses. In the field of medicine, it is often a key intermediate for the creation of new drugs. The structure of Geiinbenzothiazole is unique in biological activity, and the introduction of bromine atoms can adjust the electron cloud density and spatial structure of the molecule, thereby enhancing its interaction with biological targets. For example, based on this, antibacterial drugs can be developed, which can precisely act on specific bacterial targets, interfere with their physiological metabolism, and achieve antibacterial effect. In the development of anti-tumor drugs, it is also expected to use its unique structure to inhibit the proliferation of tumor cells.
In the field of materials science, 7-bromobenzothiazole also plays an important role. First, it can be used to prepare materials with special photoelectric properties. After appropriate chemical modification and polymerization, organic semiconductor materials with high-efficiency luminescence properties can be synthesized and applied to organic Light Emitting Diode (OLED) to improve its luminous efficiency and stability, so that the display screen presents more vivid colors. Second, in the synthesis of some functional polymer materials, it participates in the reaction as a functional monomer, endows polymer materials with characteristics such as good thermal stability and chemical stability, and expands its application in high-end fields such as aerospace and electronics.
In addition, in the field of agricultural chemistry, 7-bromobenzothiazole can be used as an important raw material for the synthesis of new pesticides. After rational design and synthesis, pesticide varieties with high-efficiency insecticidal, bactericidal or herbicidal activities are created, and because of their structural characteristics, they may have the advantages of environmental friendliness and low toxicity, providing assistance for the sustainable development of modern agriculture.

To prepare 7-bromobenzothiazole, the following ancient method can be followed. First take benzothiazole as the base, which is important in the chemical process. Add bromine to the 7th position of benzothiazole by bromination.
Usually use a suitable brominating agent, such as bromine (Br ²) or N-bromosuccinimide (NBS). If bromine is used, it should be handled with caution because it is highly corrosive and volatile. In an inert atmosphere, such as nitrogen, dissolve benzothiazole into a suitable solvent, such as dichloromethane or carbon tetrachloride. Cold to a suitable temperature, or in an ice bath, slowly drop bromine and stir at the same time to make it smooth.
If N-bromosuccinimide is used, it is milder and easier to operate. Benzothiazole is also dissolved in a solvent, such as chloroform, and an initiator, such as benzoyl peroxide, is added to heat or light to introduce. NBS will gradually release bromine, and benzothiazole should be formed into 7-bromobenzothiazole at 7 positions.
The product should be treated by a conventional method. If the method of extraction is used, the product should be extracted from the reaction solution with a suitable solvent, then washed with water, dried, and removed. After distillation and recrystallization, pure 7-bromobenzothiazole can be obtained. These methods are selected according to the purity of raw materials, equipment and products.

I don't know what the price range of "Benzothiazole, 7 - bromo -" is in the market. This is a chemical substance, and its price varies depending on various factors such as purity, supplier, purchase volume, market supply and demand.
If you want to know the exact price, you can go to the chemical trading platform, such as Sinopharm Group Chemical Reagent official website, search banner reagent network, etc. In this way, you can observe the prices quoted by each supplier, and the prices are different for different purity and packaging specifications. Or you can contact the chemical reagent dealer to inquire about the quotation of this substance. Or participate in chemical industry exhibitions and seminars to communicate with industry insiders, and you can also get relevant price information. < Br >
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