Benzothiazole 2 P Aminophenyl 6 Methyl
quinoline thiophene imidazole thiazole

Benzothiazole, 2-(p-aminophenyl)-6-methyl-

    Specifications

    HS Code

    597197

    Chemical Formula C14H12N2S
    Molecular Weight 240.328 g/mol
    Appearance Solid (usually powder)
    Melting Point 177 - 181 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, chloroform
    Odor Typically odorless
    Color Light - colored (usually white to off - white)
    Density Approx. 1.28 g/cm³
    Stability Stable under normal conditions, may decompose on heating
    Pka No available common data
    Logp Estimated to be relatively lipophilic

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    General Information
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    Frequently Asked Questions

    As a leading Benzothiazole, 2-(p-aminophenyl)-6-methyl- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of Benzothiazole, 2- (p-aminophenyl) -6-methyl-?
    Benzothiazole, 2- (p-aminophenyl) -6-methyl, has a wide range of uses. In the field of medicine, it can be used as a key intermediate in drug synthesis. Many drugs with special curative effects often rely on their participation in synthesis, or enhance drug activity, or optimize drug molecular structure to achieve better therapeutic efficacy, such as targeted drugs for specific diseases, benzothiazole derivatives may be able to precisely act on lesions to improve therapeutic accuracy and effect.
    In the field of materials, it also shows unique properties. It can be used as a component of functional materials to impart fluorescent properties such as fluorescence properties to the preparation of fluorescent detection materials, which can sensitively detect specific substances, which is of great significance in environmental monitoring, biological analysis, etc.; or to enhance material stability, corrosion resistance, and expand the application range of materials, such as protective materials used in special environments.
    In agriculture, it may have potential value. Or it can be rationally derived and modified to make pesticide intermediates, synthesize pesticides with high insecticidal and bactericidal properties, help agricultural pest control, ensure crop yield and quality, and maintain agricultural ecological balance in a green, environmentally friendly and efficient way.
    In addition, in the field of scientific research, as an important chemical substance, it provides a key foundation for the research of organic synthetic chemistry, medicinal chemistry and other disciplines. Through in-depth research and derivative development, researchers continue to expand the boundaries of chemical synthesis, explore new chemical reaction paths and functional materials, and promote the sustainable development of related disciplines.
    What are the physical properties of Benzothiazole, 2- (p-aminophenyl) -6-methyl-?
    2 - (p-Aminophenyl) -6 -methylbenzothiazole, this is an organic compound. Its physical properties are unique and are hereby described in detail by Jun.
    Looking at its appearance, it is often in a crystalline state, with pure white color and fine and uniform. Its melting point is significant, about [X] ° C. At this temperature, the solid phase will gradually transform into a liquid phase, which is caused by the change of intermolecular forces. This property is crucial in separation, purification and identification experiments, and can be an important basis for judging its purity.
    Discusses solubility, which has certain solubility in organic solvents such as ethanol and acetone. Ethanol is a common organic solvent. When it dissolves with it, the compound can be evenly dispersed due to the interaction between the two molecules, either van der Waals force or hydrogen bond. However, in water, its solubility is not good, because the polarity of water molecules and the structure of the compound are quite different, making it difficult for the two to blend.
    Its density is also of characterization significance, about [X] g/cm ³. The value of density is related to the mass of the molecule and the way of packing. This parameter has far-reaching influence in the fields of chemical production and material preparation. For example, when designing reaction vessels and considering the ratio of materials, density is an indispensable parameter.
    Furthermore, its stability is also the focus of attention. Under normal temperature and pressure, dark and dry conditions, the compound can maintain a relatively stable state. However, in case of strong acid, strong base or extreme conditions such as high temperature and light, its structure may change, triggering a chemical reaction and causing its properties to change. The physical properties of
    2- (p-aminophenyl) -6-methylbenzothiazole are of great value in chemical research and industrial production. It lays a solid foundation for in-depth exploration of its chemical behavior and expansion of application fields.
    What are the chemical properties of Benzothiazole, 2- (p-aminophenyl) -6-methyl-
    2 - (p-aminophenyl) -6 -methylbenzothiazole, this is an organic compound. Its chemical properties are unique and have many important properties.
    From a structural perspective, the benzothiazole ring is connected to p-aminophenyl and methyl, which gives it a specific electronic effect and spatial configuration. Because the benzothiazole ring contains nitrogen and sulfur heteroatoms, it has certain aromatic properties and electron cloud distribution characteristics, while the amino group of p-aminophenyl has electron-donating properties, and methyl is the power supply group, these groups interact and greatly affect the chemical properties of the compound.
    In terms of physical properties, its solubility may vary depending on the polarity of the molecule. Contains a polar group amino group, or has a certain solubility in a polar solvent; the aromaticity and relative molecular mass of the overall structure, or cause its melting point and boiling point to reach a certain value.
    In terms of chemical activity, amino groups can participate in many reactions, such as salting with acids, acylating with acid chlorides or acid anhydrides, thereby introducing various functional groups to derive different products. On the benzothiazole ring, due to the influence of nitrogen and sulfur atoms, electrophilic substitution reactions can occur, and the substitution check point is affected by the positioning effect of existing groups on the ring. Although the methyl group is relatively stable, it can be oxidized under specific conditions, such as the action of strong oxidants.
    In addition, this compound may have potential applications in the field of optical materials due to its conjugated structure or certain optical properties, such as fluorescence properties. Its chemical properties have attracted much attention in the fields of medicinal chemistry and materials science, or it is a key intermediate for the creation of new drugs and the development of functional materials.
    What is the synthesis method of Benzothiazole, 2- (p-aminophenyl) -6-methyl-?
    The method of preparing 2 - (p-aminophenyl) -6 -methylbenzothiazole has been known for a long time. The first method requires selecting suitable raw materials, using p-nitroaniline and o-methylthiobenzoic acid as the starting materials, both of which are the key bases for the preparation of the compound.
    First, the o-methylthiobenzoic acid interacts with an appropriate amount of reagents, acylates it, and converts its structure to form a specific intermediate. This process requires observing the reaction conditions, such as temperature, reaction time and reagent dosage. If the temperature is too high or too low, the reaction may deviate from expectations, or the reaction rate may be delayed, or side reactions may occur.
    At the same time, p-nitroaniline also needs to be converted into p-phenylenediamine by reduction method. The reduction method can be achieved by means of metal and acid system, or hydrogenation reduction under catalytic conditions. The key to this step is to ensure the complete reduction reaction and avoid excessive reduction to obtain pure p-phenylenediamine.
    Then, the obtained intermediate is mixed with p-phenylenediamine, and in a specific solvent, through condensation reaction, the core structure of benzothiazole is constructed. For this condensation reaction, the choice of solvent is crucial, and the solubility of the solvent to the reactants and the promotion of the reaction need to be considered. During the reaction process, it is also necessary to closely monitor the reaction process. TLC and other means can be used to clarify the degree of reaction.
    After the reaction is completed, the impurities are removed by separation and purification techniques, such as column chromatography, recrystallization, etc., and the final pure 2- (p-aminophenyl) -6-methylbenzothiazole is obtained. These steps are interconnected and need to be carefully controlled to make the preparation process smooth and obtain the expected product.
    Benzothiazole, 2- (p-aminophenyl) -6-methyl - Is there a safety risk?
    Fubenzothiazole, 2 - (p-aminophenyl) -6 - methyl, its safety is related to the health of the user and cannot be ignored.
    This substance has not been detailed in "Tiangong Kaiwu". However, in today's world, there are many chemical substances, and their properties are difficult to measure. This substance may involve the field of chemical industry and medicine. If it is synthesized, the raw materials used and the reaction conditions are the main reasons. Whether the raw materials are pure or not is related to the existence of impurities, impurities or toxicity and allergies. If the reaction conditions are not good, it may also cause side reactions to be raw, and the product is impure, and its safety is worrying.
    At the time of application, if it is a medicine, the way into the body and the dosage should be cautious. The medicine taken internally must be absorbed through the stomach and metabolized by the liver, and its impact on the viscera must be carefully investigated. The agent used externally also considers the possibility of skin absorption and irritation. If it is used in chemical industry, the risk of volatilization and leakage must also be prevented. Volatile gas enters the respiratory tract of people, or damages the lungs; leaking places, or polluting soil and water sources, and ecological harm should not be underestimated.
    Although the exact safety risk of this product is not yet known, it is common sense to be cautious in all aspects of research and development, production, and application. Detailed testing should be done to explore its toxicology, pharmacology, and environmental impact before it can be guaranteed to be safe and ecological. Be careful to protect the well-being of all beings and keep the world peaceful.