Benzothiazol-2-yl (Z)-2-methoxyimino-2-(2-aminothiazole-4-yl)thioacetate

This is the chemical structure of benzothiazole-2-yl (Z) -2-methoxyimino-2- (2-aminothiazole-4-yl) thioacetate. Its structure contains a benzothiazole part, which is a structural unit formed by fusing a benzene ring with a thiazole ring, with specific aromaticity and stability. (Z) -2 -methoxyimino part exists in a specific spatial configuration, and the methoxy group is connected to the imino group, which has an impact on the electron cloud distribution and reactivity of the molecule as a whole. 2 - (2-aminothiazole-4-yl) thioacetate moiety, the thiazole ring has an amino group at the 2nd position, and the thioacetate is connected at the 4th position. The sulfur atom plays a connecting role in it, and the thiazole ring is connected to the acetate moiety. The interaction of various parts in this structure determines the physical and chemical properties of the compound, and it may have specific uses and reaction characteristics in the fields of medicinal chemistry, organic synthesis, etc.

Benzothiazole-2-yl (Z) -2-methoxyimino-2- (2-aminothiazole-4-yl) thioacetate is an organic compound. It has a wide range of uses in the field of medicine and is often used as a key intermediate for antibacterial drugs. Due to its specific chemical structure, it can participate in many chemical reactions and help synthesize compounds with antibacterial activity, contributing to the resistance to bacterial invasion and the protection of human health.
In the field of pesticides, it also plays an important role. It can be used as a raw material for the synthesis of new pesticides. Through ingenious design and synthesis, pesticides that have high toxic effects on pests but have little impact on the environment and non-target organisms can be created. In this way, it can not only effectively prevent and control crop diseases and pests, ensure food yield and quality, but also meet the needs of modern green agriculture development, and help protect the ecological environment.
In addition, in the field of organic synthetic chemistry research, this compound is often regarded as an important building block by chemists because of its unique structure and reactivity. With its special properties, it can carry out diverse organic reactions and synthesize complex and novel organic molecules, thus promoting the continuous development of the field of organic synthetic chemistry, laying the foundation for the research and development of new materials and other fields, and helping many related industries to make new breakthroughs.

The method of preparing benzothiazole-2-yl (Z) -2-methoxyimino-2 - (2-aminothiazole-4-yl) thioacetate has been studied a lot in ancient times. One method is also to start with 2-aminothiazole-4-carboxylic acid, and then interact with carbon disulfide and base to obtain the corresponding xanthate, and then react with haloacetate to obtain a thioester-containing precursor. Then, the precursor is reacted with methoxylamine hydrochloride in the presence of an appropriate base to construct a methoxyimino structure, and the final product is obtained.
Another method is to use 2-aminothiazole-4-yl thioacetate as the starting material, first protect the amino group with an appropriate protective group to prevent it from interfering in the subsequent reaction. Then, react with methoxylamine and an appropriate condensing agent, such as carbodiimide, in a suitable solvent to form a methoxy imino structure. Finally, the protective group can also be removed to obtain the target compound.
Another way is to react benzothiazole-2-mercaptan with (Z) -2-methoxyimino-2- (2-aminothiazole-4-yl) acetyl halide under base catalysis. Potassium carbonate, triethylamine, etc. can be selected as a base. In organic solvents such as dichloromethane, N, N-dimethylformamide, through nucleophilic substitution reaction, thiol groups are reacted with acyl halides to obtain benzothiazole-2-yl (Z) -2-methoxyimino-2 - (2-aminothiazole-4-yl) thioacetate.
This method has its own advantages and disadvantages. In actual preparation, the appropriate synthesis path needs to be carefully selected according to many factors such as the availability of raw materials, the difficulty of reaction conditions, the purity and yield of the product.

This is benzothiazole-2-yl (Z) -2-methoxyimino-2 - (2-aminothiazole-4-yl) thioacetate. Its physical and chemical properties are quite important and affect many application fields.
In terms of appearance, it is often in the state of white to off-white crystalline powder, with fine texture and purity in appearance. This appearance characteristic is of great significance in pharmaceutical and chemical production, because the purity state often indicates high purity, which is conducive to subsequent product preparation.
In terms of melting point, it is about 160-165 ° C. Melting point is the inherent characteristic of the substance, which can be used as the basis for identification and purity judgment. Accurate melting point data helps to control the quality and ensure that the product meets specific standards.
Solubility cannot be ignored. It is slightly soluble in water, but soluble in organic solvents such as dichloromethane, N, N-dimethylformamide. This solubility characteristic determines its application in different reaction systems and preparation processes. In organic synthesis reactions, dissolution and reaction can be achieved with the help of suitable organic solvents to improve the reaction efficiency.
Stability is also a key property. In a dry environment at room temperature, this substance is relatively stable. However, if exposed to high temperature, high humidity or strong light conditions, it may decompose or deteriorate. Therefore, storage conditions need to be strictly controlled, often in a cool, dry and dark place to ensure its quality and activity.
In addition, the groups such as benzothiazole, aminothiazole and methoxyimino contained in its molecular structure give it unique chemical activity and reaction characteristics. These groups can participate in many chemical reactions, such as nucleophilic substitution and addition reactions, laying the foundation for the synthesis of new derivatives or drugs, and have potential application value in the field of medicinal chemistry.

What is the situation of benzothiazole-2-yl (Z) -2-methoxyimino-2 - (2-aminothiazole-4-yl) thioacetate in the market today? This substance is an important intermediate involved in the field of organic synthesis.
In the past, it attracted the attention of many researchers because of its potential use in various fields such as medicine and pesticide creation. In medicine, it may be used as a key raw material for the synthesis of antibacterial and antiviral drugs, so the market demand trend was initially on the rise.
Looking at the current market situation, with the gradual improvement of the synthesis process, its output has also increased. However, due to the complicated steps in the preparation process and the high technical requirements, most of them are manufacturers with profound technical background and sophisticated equipment.
And its price is relatively high due to the fluctuation of raw material costs and the maintenance of synthesis difficulty. On the downstream demand side, the development of the pharmaceutical industry is still its main driving force. With the advancement of new drug research and development, the demand for it may still maintain stable growth. However, the state of market competition is also becoming more and more intense because of the profitability. All manufacturers are seeking to optimize the process, reduce costs and increase efficiency, and strive for a place in the market. Overall, benzothiazole-2-yl (Z) -2-methoxyimino-2 - (2-aminothiazole-4-yl) thioacetate is in the market, with both opportunities and challenges, and the prospect is still promising.