What are the main uses of 2- (2-aminothiazole-4-yl) acetic acid?

2-%282-%E6%B0%A8%E5%9F%BA%E5%99%BB%E5%94%91-4-%E5%9F%BA%29%E4%B9%99%E9%85%B8%EF%BC%8C%E5%8D%B32- (2-aminopyridine-4-yl) acetic acid, this compound has many main uses.

In the field of medicinal chemistry, it is often a key intermediate. In the process of drug development, it plays an important role in building the molecular framework of drugs. Geinaminopyridine and acetic acid structural fragments have unique chemical and biological activities, and can be chemically modified to connect with other structural units to synthesize compounds with specific pharmacological activities. For example, in the development of antimicrobial drugs, by modifying its structure, the final product can exhibit strong inhibition or killing ability against specific bacteria; in the field of anticancer drugs, it can be used to construct targeted anticancer drug molecules to improve the accuracy of drug action on cancer cells, while reducing damage to normal cells.

In the field of organic synthesis, it is an important starting material for the construction of complex organic molecules. Due to the existence of amino groups, pyridine rings and carboxyl groups, a variety of classical organic reactions can occur, such as amidation reactions, esterification reactions, nucleophilic substitution reactions, etc. Through these reactions, different functional groups can be introduced into molecules to expand the diversity of molecular structures, and then organic compounds with different physical and chemical properties can be synthesized to meet the needs of materials science, fine chemistry and other fields. For example, when synthesizing high-performance organic optoelectronic materials, conjugated structures can be constructed with the help of this compound to improve the photoelectric conversion efficiency of the material.

In the field of coordination chemistry, its amino and carboxyl groups can act as ligands to coordinate with metal ions to form metal complexes. These metal complexes often have unique physical, chemical and biological properties, and have potential applications in catalysis, biosensing, magnetic materials, etc. For example, in catalytic reactions, complexes formed by ligands and transition metals can efficiently catalyze certain organic reactions, improving reaction rate and selectivity.

What are the physical and chemical properties of 2- (2-aminothiazole-4-yl) acetic acid?

2 - (2-aminopyridine-4-yl) acetic acid, this is an organic compound. Its physical and chemical properties are worth exploring.

Looking at its properties, it is mostly white to off-white solid powder under normal conditions, and this morphology is easy to identify and distinguish. In terms of solubility, it is slightly soluble in water, but soluble in common organic solvents such as ethanol and dichloromethane. This property is of great significance in the separation, purification and solvent selection of compounds.

When it comes to the melting point, it is measured to be in a specific temperature range. This data provides an important reference for the purity identification of compounds. Due to its different purity, the melting point may be deviated.

From the chemical properties, there are amino and carboxyl groups in the compound molecule. Amino groups have certain alkalinity and can neutralize with acids to form corresponding salts. The carboxyl group is acidic and can react with bases to form carboxylic salts. Not only that, carboxyl groups can also participate in esterification reactions and form ester compounds with alcohols under specific conditions.

Due to the presence of pyridine rings in its structure, compounds endow unique electronic and spatial effects, making them often used as key intermediates in the field of organic synthesis. In pharmaceutical chemistry research, molecular structures with specific biological activities can be chemically modified, providing the possibility for the development of new drugs.

What are the synthesis methods of 2- (2-aminothiazole-4-yl) acetic acid?

To prepare 2 - (2 - hydroxypropyl - 4 - yl) acetic acid, there are various methods. First, the method of nucleophilic substitution can be borrowed. First, take the appropriate halogenated hydrocarbon, make it meet with the nucleophilic reagent containing hydroxyl groups and specific groups. Under suitable conditions, the halogen atom is replaced by the nucleophilic reagent, and the intermediate containing the target skeleton is initially formed. Then, by hydrolysis, acidification and other steps, the intermediate is converted into the desired 2 - (2 - hydroxypropyl - 4 - yl) acetic acid. In this process, the selection of halogenated hydrocarbons is very critical, and its activity and reaction selectivity need to be considered, so that the nucleophilic substitution can occur precisely at the desired check point.

Second, we can think of the reaction using Grignard reagents. First prepare a halogenate containing a specific group, so that it reacts with magnesium to form Grignard reagents. This Grignard reagent is active and can react with carbonyl-containing compounds such as alaldehyde or ketone. After addition and hydrolysis, the carbon frame of the target molecule is constructed. Subsequent to the appropriate functional group conversion, the final 2 - (2-hydroxypropyl-4-yl) acetic acid is obtained. The conditions for the reaction of Grignard reagents need to be carefully controlled. An anhydrous and anaerobic environment is essential to ensure the success of the reaction, and the proportion of reactants also has a significant impact on the yield and purity of the product.

Third, a condensation reaction strategy may be adopted. Select small molecule compounds containing active functional groups, such as esters or aldones. Under the action of basic or acidic catalysts, the condensation reaction will gradually increase the carbon chain and introduce the required functional groups. There are many types of condensation reactions, such as Claisen condensation, hydroxyaldehyde condensation, etc., which need to be used according to the structural characteristics of the target molecule. During the reaction, factors such as the type and dosage of catalysts, reaction temperature and time need to be carefully adjusted to achieve the best reaction effect and obtain high-purity 2 - (2-hydroxypropyl-4-yl) acetic acid.

What is the price range of 2- (2-aminothiazole-4-yl) acetic acid in the market?

I don't know the price of "2- (2-hydroxypyridine-4-yl) acetic acid" in the market. However, if you want to know its price, you can explore it from multiple sources.

First, various chemical reagent dealers in the city may have this product for sale. You can consult a shop specializing in chemical materials, such as Sinopharm Group Chemical Reagent Co., Ltd. Its price may vary depending on the quantity and quality. If the purchase quantity is quite large, the business may be beneficial, and the price should be slightly reduced; if the quality is good, the price may be slightly higher.

Second, the online chemical product trading platform is also a way to explore the price. Such as Gade Chemical Network, Mobell Chemical, etc. Such platforms gather many suppliers, and the prices are different. Looking at the quotation, you can get a glimpse of the approximate price in the market. However, if the price on the line is not true, it is advisable to discuss with the merchant in detail to confirm the authenticity of the price and whether it can be changed.

Third, consult scientific research institutions and university laboratories. They often need to use such chemicals, and their price may be known. Talk to their researchers and experimenters, or you can get useful price information.

In general, the price of "2- (2-hydroxypyridine-4-yl) acetic acid" in the market varies depending on factors such as suppliers, purchase quantity, quality, etc. If you want to determine the price, you need to explore and compare it many times.

What are the storage conditions for 2- (2-aminothiazole-4-yl) acetic acid?

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This medicine should be placed in a cool, dry, well-ventilated place, away from direct sunlight. Ultraviolet rays in sunlight may cause chemical changes in drug components, affecting their efficacy. And too high temperature may lead to changes in the molecular structure of the drug, thereby reducing the drug activity; too high humidity is easy to make the drug damp, may cause mildew, deterioration, etc., and damage the quality of the drug.

should be placed out of the reach of children. Because it is a chemical drug, if it is taken by children by mistake, it may cause serious adverse reactions and endanger life and health because children's physical functions are not fully developed and their tolerance to the drug is poor.

Store away from fire sources and strong oxidants. 2- (2-aminopyridine-4-yl) acetic acid has a certain chemical activity. In case of open flame or strong oxidant, dangerous chemical reactions such as combustion and explosion may occur, which will not only damage the drug, but also cause safety accidents and cause serious harm to the storage environment and personnel.

Keep the packaging intact during storage. If the packaging is damaged, the drug is directly exposed to the external environment, which is more susceptible to temperature and humidity, air composition, etc., and accelerates the deterioration of the drug. At the same time, the drug information on the packaging is also crucial for the correct use of the drug. Damage to the packaging may lead to missing or ambiguous information and affect the safety of the drug.