Amino 5 Nitro Benzo Isothiazole
quinoline thiophene imidazole thiazole

AMINO-5-NITRO BENZO-ISOTHIAZOLE

    Specifications

    HS Code

    834002

    Chemical Formula C7H4N2O3S
    Molecular Weight 196.18 g/mol
    Appearance Solid
    Color Yellow to orange
    Odor Typical organic compound odor
    Melting Point 198 - 202 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO, DMF
    Density Approx. 1.61 g/cm³
    Stability Stable under normal conditions, may decompose on heating or under strong oxidizing agents
    Pka No data available
    Flash Point No data available

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    General Information
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    Frequently Asked Questions

    As a leading AMINO-5-NITRO BENZO-ISOTHIAZOLE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of AMINO-5-NITRO BENZO-ISOTHIAZOLE?
    "AMINO-5-NITRO + BENZO - ISOTHIAZOLE" refers to "Amino-5-nitro-benzoisothiazole". This is an organic compound and is widely used in the field of chemistry.
    Its chemical structure is constructed on the parent nucleus of benzoisothiazole. Benzoisothiazole is formed by fusing a benzene ring with an isothiazole ring. The isothiazole ring contains sulfur and nitrogen heteroatoms, which endow the structure with unique reactivity and stability.
    In "amino-5-nitro-benzoisothiazole", a nitro group (-NO ³) is introduced at the 5th position, which is a strong electron-absorbing group. The introduction of this group greatly changes the distribution of molecular electron clouds, enhances the oxidation of compounds, and affects their chemical activity and reaction check point selectivity.
    The amino group (-NH2O) is also connected to the benzoisothiazole structure. The amino group is a power supply group and can interact with the nitro group to affect the overall polarity and chemical reactivity of the molecule. It can participate in a variety of reactions, such as nucleophilic substitution, condensation reactions, etc., providing the possibility for the derivatization and functionalization of compounds.
    In this way, the chemical structure of "amino-5-nitro-benzoisothiazole" presents unique chemical properties and reactivity due to the synergy of benzoisothiazole parent nucleus and nitro and amino groups, and has important potential value in pharmaceutical chemistry, materials science and other fields.
    What are the physical properties of AMINO-5-NITRO BENZO-ISOTHIAZOLE
    Amino-5-nitro-benzoisothiazole, this is an organic compound. Its physical properties are particularly important and are related to many application fields.
    First talk about the appearance, usually in a solid state, mostly in the shape of light yellow to brown powder. This color and morphology are its intuitive characteristics, which can be preliminarily judged in actual operation and identification.
    In terms of melting point, it is about a specific temperature range. This property is crucial for the purification and identification of compounds. If the melting point is accurately determined, it can help to determine the purity of the substance. The melting point is often offset due to the presence of impurities.
    Solubility is also an important physical property. In common organic solvents, such as ethanol, acetone, etc., there is a certain solubility. However, in water, the solubility is relatively poor. This difference in solubility can be exploited in chemical synthesis, separation and purification. For example, to separate this compound from a mixture, a suitable solvent can be selected for extraction operation according to its solubility in different solvents.
    In terms of density, it has a specific value. Although density is not the most critical consideration in general chemical experiments, its density data is also indispensable in some scenarios involving accurate measurement or mixing ratio of substances.
    Furthermore, its stability is also in the category of physical properties. It is relatively stable at room temperature and pressure without special chemical reaction conditions. However, under special conditions such as high temperature and strong oxidants, decomposition or other chemical reactions may occur. This stability knowledge is particularly important when storing and transporting the compound. It is necessary to properly select the storage environment and transportation conditions to ensure safety.
    In summary, the physical properties of amino-5-nitro-benzoisothiazole, from appearance, melting point, solubility, density to stability, play a key role in its research, production and application in the field of chemistry.
    What is the main use of AMINO-5-NITRO BENZO-ISOTHIAZOLE?
    AMINO - 5 - NITRO + BENZO - ISOTHIAZOLE (5 - amino - 5 - nitrobenzoisothiazole) is widely used.
    In the field of medicine, it can be used as a key intermediate for the synthesis of many specific drugs. Due to its unique chemical structure and activity, it can be chemically modified and modified to derive compounds with specific pharmacological activities. For example, targeted therapeutic drugs for some difficult diseases, using it as the starting material, through multi-step fine synthesis, it is expected to develop new drugs with high efficiency and small side effects, bringing good news to patients.
    In the field of materials science, it also has outstanding performance. Can be used to prepare functional materials with special properties. For example, introducing it into the polymer material system can impart excellent properties such as antibacterial and antioxidant properties to the material. These materials can be used in the field of food packaging to extend the shelf life of food; or in medical and health materials to reduce the risk of infection.
    In the field of agriculture, it can be used as an important precursor compound for the creation of new pesticides. After rational structure optimization, it is expected to develop high-efficiency, low-toxicity and environmentally friendly pesticide products, which can help the development of precision agriculture. It can not only effectively control pests and diseases, but also reduce the adverse impact on the environment and maintain ecological balance.
    In the level of scientific research and exploration, it is an organic compound with a special structure, providing an important model molecule for the research of organic synthetic chemistry, medicinal chemistry and other disciplines. Scientists can further explore the relationship between reaction mechanism, structure and properties, expand the boundaries of chemical knowledge, and provide new ideas and methods for the design and synthesis of new compounds.
    What are the synthesis methods of AMINO-5-NITRO BENZO-ISOTHIAZOLE?
    To prepare AMINO - 5 - NITRO + BENZO - ISOTHIAZOLE, there are many methods, which are described in detail below.
    First, it can be prepared by condensation reaction from specific raw materials containing nitrogen, nitro and benzoisothiazole structures. First, take a suitable nitrogen-containing compound and a substance containing a benzoisothiazole skeleton with reactive groups and place it in a suitable reaction vessel. Using a specific organic solvent as the medium, add an appropriate amount of catalyst, and in an environment with precise temperature control, make the two condensate. This process requires fine control of temperature, reaction time and proportion of raw materials. If the temperature is too high, or side reactions occur frequently; if the temperature is too low, the reaction will be slow and the yield will not be high. The reaction time is also critical. If it is too short, the reaction will not be completed. If it is too long, the energy consumption will increase, and there may be a risk of product decomposition. Improper proportion of raw materials will also affect the yield and purity.
    Second, it is prepared by substitution reaction. Select a compound containing benzoisothiazole parent and a substituted group, and react with a substitution reagent containing amino and nitro groups. Under specific reaction conditions, if a suitable base is selected as a promoter, in a suitable solvent system, the amino and nitro groups of the substituted reagent can selectively replace specific groups on the parent of benzoisothiazole. This reaction needs to consider the activity, selectivity of the substituted reagent and the effect of reaction conditions on the substitution position. If the activity of the substitution reagent is too high, or excessive substitution is caused; if the activity is too low, the reaction is difficult to proceed.
    Third, a multi-step synthesis strategy can also be used. The intermediate containing part of the target structure is first synthesized, and then the complete AMINO-5 - NITRO + BENZO - ISOTHIAZOLE structure is gradually constructed through multi-step reaction. Each step of the reaction requires careful operation of the reaction conditions, product separation and purification. The successful connection of each step of the reaction is crucial to the acquisition of the final product. If the intermediate product is impure, it will be carried into the next reaction, or the subsequent reaction process and product quality will be affected.
    In short, the synthesis of AMINO - 5 - NITRO + BENZO - ISOTHIAZOLE has various methods, but it is necessary to strictly control the reaction conditions, raw materials and intermediates in order to obtain the ideal product.
    What are the precautions for AMINO-5-NITRO BENZO-ISOTHIAZOLE during use?
    Amino-5-nitro-benzoisothiazole is a special chemical substance, and many matters need to be paid attention to during use.
    Bear the brunt of it, and safety protection must be comprehensive. This substance may be toxic and irritating to a certain extent, and appropriate protective equipment must be worn during operation, such as protective gloves, goggles and masks, to prevent it from coming into contact with the skin, eyes and respiratory tract, and to avoid damage to the body.
    Furthermore, accurate control of the dosage is essential. The dosage should be strictly determined according to the specific application and reaction requirements, following established standards and norms. Improper dosage may cause the reaction to go out of control, or affect the quality and performance of the final product.
    Proper storage conditions should not be ignored. It needs to be stored in a dry, cool and well-ventilated place, away from fire sources, heat sources and oxidants. Due to its active chemical properties, improper storage or danger, such as spontaneous combustion, explosion, etc.
    The ventilation condition of the use environment must be good. The operation site should be equipped with effective ventilation equipment to discharge volatile gases in time to prevent the accumulation of harmful gases and reduce the risk of poisoning.
    In addition, the reaction conditions during use need to be precisely regulated. Temperature, pressure, reaction time and other factors have a significant impact on the reaction process and product generation. If there is a slight carelessness, or side reactions occur, the purity and yield of the product will be reduced.
    Do not discard at will in waste disposal. It should be properly collected, treated and disposed of in accordance with relevant environmental regulations to avoid pollution to the environment.
    During operation, it is also necessary to pay close attention to the reaction phenomenon. If there is abnormal heat, discoloration, gas production, etc., the operation should be stopped immediately and corresponding emergency measures should be taken.
    All links in the use of amino-5-nitro-benzoisothiazole are related to safety and effect, and must not be taken lightly. Strictly follow the procedures and operate with caution.