6r N 6 Propyl 4 5 6 7 Tetrahydro 1 3 Benzothiazole 2 6 Diamine
quinoline thiophene imidazole thiazole

(6R)-N~6~-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine

    Specifications

    HS Code

    513928

    Chemical Formula C10H17N3S
    Molecular Weight 211.33

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    General Information
    Where to Buy (6R)-N~6~-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine in China?
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    Frequently Asked Questions

    As a leading (6R)-N~6~-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of (6R) -N~ 6~ -propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine?
    The chemical structure of (6R) -N~ 6~ -propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine can be described as follows according to the ancient saying of "Tiangong Kaiwu".
    This compound contains the core structure of benzothiazole, which is a heterocycle formed by fusing the benzene ring with the thiazole ring. In the thiazole ring, the sulfur atom coexists with the nitrogen atom, giving the ring unique chemical activity. < Br >
    In the 4,5,6,7-tetrahydro part, it refers to the partial hydrogenation of the benzene ring, that is, adding hydrogen atoms at the 4,5,6,7 positions of the benzene ring, causing the originally aromatic benzene ring to be partially saturated, forming a tetrahydrobenzothiazole structure with a special spatial structure and electron cloud distribution.
    Furthermore, at the 2,6 positions, there is a diamine group, which is a nitrogen-containing functional group. The nitrogen atom has lone pair electrons, which makes the compound basic and nucleophilic, and can participate in many chemical reactions.
    And (6R) indicates that the three-dimensional configuration at carbon 6 is R-type, which is determined by the Cahn-Ingold-Prelog rule, which is related to the spatial arrangement of molecules and has a great impact on their physical, chemical and biological activities.
    As for N~ 6~ -propyl, it means to connect a propyl group to the No. 6 nitrogen atom. Propyl is an alkyl group containing three carbon atoms. Its introduction increases the lipophilicity of the molecule and affects the solubility of the compound in different media and the interaction with other molecules. In this way, (6R) -N~ 6~ -propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine has its unique chemical structure and properties.
    What are the main uses of (6R) -N~ 6~ -propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine?
    (6R) -N- (6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine) is widely used. In the field of medicine, it is often used as a key intermediate to help synthesize drugs with excellent efficacy. The development of many new antidepressant drugs is based on it, and with the help of specific chemical reactions, compounds with more complex structures and excellent antidepressant activities are constructed, bringing good news to many depressed patients.
    In the chemical industry, it also plays an important role in the preparation of some special materials. It can participate in the synthesis process of polymer materials and optimize material properties, such as enhancing material stability, improving material mechanical properties, etc., so that the synthesized materials can meet the demanding needs of special fields such as aerospace, high-end electronic equipment manufacturing, etc.
    At the level of scientific research and exploration, it provides a unique chemical structure for chemical research. By in-depth exploration of its chemical reaction characteristics, researchers expand the boundaries of organic chemistry knowledge, develop novel synthesis methods and strategies, promote the vigorous development of chemical disciplines, and lay a solid theoretical foundation for technological innovation in many fields.
    What is the preparation method of (6R) -N~ 6~ -propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine?
    (6R) -N~ 6~ -propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine is an organic compound, and the preparation method is as follows:
    The starting material is selected from the appropriate sulfur-containing and nitrogen-containing compounds. For example, 2-chloromethyl-4,5,6,7-tetrahydrobenzothiazole derivatives and propylamine are used as starting materials. In a suitable reaction vessel, place 2-chloromethyl-4,5,6,7-tetrahydrobenzothiazole derivatives in an appropriate amount of organic solvents, such as N, N-dimethylformamide (DMF), dichloromethane, etc., and stir thoroughly to dissolve.
    Then, slowly add propylamine. The amount of propylamine needs to be precisely adjusted according to the stoichiometric ratio. Generally, it is slightly excessive to promote the reaction to proceed fully. After the addition is completed, the reaction is carried out within a specific temperature range, and the reaction temperature may be maintained between 40 ° C and 80 ° C. This temperature range can be precisely controlled by oil or water bath. During the reaction process, continuous stirring is used to fully contact the reactants. The reaction takes several hours. The specific time depends on the reaction process. It is determined by thin chromatography (TLC) or high-performance liquid chromatography (HPLC) monitoring.
    When the reaction reaches the expected level, the reaction liquid is cooled to room temperature. After that, a post-treatment operation is carried out. The reaction is quenched with water, and then the product is extracted with a suitable organic solvent, such as ethyl acetate, and the product is extracted multiple times to improve the The organic phases were combined and dried with anhydrous sodium sulfate to remove the moisture in the organic phase. After filtering to remove the desiccant, the organic solvent was distilled under reduced pressure to remove the crude product. The crude product was further purified by column chromatography, and a suitable silica gel was selected as the stationary phase. A solution mixed with petroleum ether and ethyl acetate in a certain proportion was used as the mobile phase. After this operation, high-purity (6R) -N~ 6~ -propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine products could be separated. In this way, the preparation of the compound was completed.
    What are the physical properties of (6R) -N~ 6~ -propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine?
    (6R) -N- (6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine) is a special substance for chemical synthesis, and its physical properties are crucial for its application in various fields.
    The first to bear the brunt is the appearance characteristics. Generally speaking, (6R) -N- (6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine) is mostly white to off-white crystalline powder, which is easy to observe and identify, and the powder shape is conducive to subsequent processing and treatment.
    Secondly, the melting point is also one of the important physical properties. After many experiments, its melting point is in a specific temperature range. This melting point data is of great significance for the purity identification and thermal stability study of this substance. At a specific temperature, the substance changes from solid to liquid, and the temperature range of this process is an important basis for identifying its quality.
    Furthermore, the solubility cannot be ignored. In common organic solvents, such as ethanol, methanol, etc., (6R) -N- (6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine) exhibits a certain solubility. Although its solubility in water is limited, it can be well dissolved in some organic solvents. This property provides convenience for its application in drug development, chemical reaction and other fields. Suitable solvents can be selected for reaction or preparation according to their solubility.
    In addition, the determination of density is also the key to understanding the physical properties of the substance. Appropriate density data can help to determine its existence state and behavior in a specific environment. Whether it is during storage or use, density has important reference value for the calculation of its dosage and the proportion control when mixed with other substances.
    In summary, the physical properties of (6R) -N- (6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine) cover the aspects of appearance, melting point, solubility and density. These properties are interrelated and together determine its characteristics and uses in scientific research and practical applications.
    What is the market outlook for (6R) -N~ 6~ -propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine?
    (6R) -N- (6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine) This compound has a lot to do with the current market prospects.
    In the field of Guanfu Medicine, this compound may have special pharmacological activity. In its structure, the skeleton of benzothiazole is related to propyl and diamine groups, or it can be compatible with specific targets in organisms. Therefore, it may be a potential lead compound in the development of new drugs. If the success of research and development can be used to treat specific diseases, such as diseases of the nervous system, or immune regulation, it is expected to open up new paths, and its market demand will also be considerable.
    Furthermore, in the field of chemical synthesis, the exploration and optimization of its synthesis path can contribute to the development of organic synthetic chemistry. If an efficient and green synthesis method can be found, it can not only reduce its production cost, but also enhance its competitiveness in the market. The advancement of synthesis technology may also trigger a chain reaction in related industries, driving the development of upstream and downstream products and expanding the boundaries of the market.
    However, the market prospect is not smooth. The road of new drug research and development is long and difficult, and it needs to go through many rigorous tests, such as pharmacology, toxicology and clinical trials. Only after this hurdle can it be launched. In chemical synthesis, it is not easy to find an efficient synthesis method, which requires a lot of manpower, material resources and time. But overall, (6R) -N- (6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine) has broad market prospects if it is well developed and utilized in the fields of medicine and chemical industry, which is expected to bring new opportunities and changes to the industry.