6-Methoxy-2-aminobenzothiazole

6-Methoxy-2-aminobenzothiazole, an organic compound, is widely used in the chemical and pharmaceutical fields.
In the chemical field, one of them is used as an intermediary for organic synthesis. Because of its specific chemical structure and activity, it can be converted into other organic compounds through a series of chemical reactions. For example, it can participate in nucleophilic substitution, cyclization and other reactions to synthesize more complex organic molecules, laying the foundation for the preparation of special materials, dyes, etc. For example, by reacting with suitable reagents, compounds with unique optical or electrical properties can be constructed for the research and development of new optoelectronic materials.
In the field of medicine, this compound has key uses. On the one hand, it may have biological activity, and after research and exploration, it may become a potential drug lead compound. Scientists can develop new drugs by modifying and optimizing its structure to improve its pharmacological activity, selectivity and pharmacokinetic properties. For example, in the development of antibacterial drugs, it is used as a starting material, and after structural modification, new antibacterial agents with high inhibitory effect on specific pathogens may be obtained. On the other hand, it may also be an important intermediate for the synthesis of some existing drugs. In the synthesis route of many marketed drugs, 6-methoxy-2-aminobenzothiazole is a key link. After subsequent reaction steps, the drug with definite efficacy is finally prepared.
In conclusion, 6-methoxy-2-aminobenzothiazole plays an important role in organic synthesis and drug development and manufacturing in the chemical and pharmaceutical industries due to its unique chemical properties and potential biological activities, providing key support for the development of related fields.

The synthesis method of 6-methoxy-2-aminobenzothiazole has been known for a long time. There are many methods, so let me explain them one by one.
First, using o-methoxy aniline as the starting material, it is first reacted with ammonium thiocyanate to generate the corresponding thiourea derivative. This reaction needs to be controlled in an appropriate solvent, temperature and reaction time to ensure the smooth progress of the reaction. Then, it is cyclized under acidic conditions, and after ingenious intramolecular rearrangement, the benzothiazole ring is formed, and then 6-methoxy-2-aminobenzothiazole is obtained. In this path, the raw material is easy to obtain, and the reaction steps are relatively clear. However, the control of the reaction conditions needs to be precise to obtain a higher yield.
Second, 2-hydroxy-6-methoxybenzothiazole can also be used as a substrate to prepare the target product through amination reaction. In the presence of suitable amination reagents and catalysts, the reaction system is heated to replace the hydroxyl group with the amino group. This process requires attention to the activity and selectivity of the reagent to avoid the occurrence of side reactions, which can effectively improve the purity and yield of the product.
Third, starting from 6-methoxybenzothiazole-2-one, it is synthesized by reductive amination reaction. First, the ketone carbonyl is reduced to a hydroxyl group, and then reacted with ammonia or amine compounds under the action of catalysts to achieve the introduction of amino groups. The key to this method is the connection between reduction and amination steps, as well as the selection and dosage of catalysts. Proper operation can make the reaction proceed efficiently.
All synthesis methods have their own advantages and disadvantages. The synthesizer should carefully choose according to the actual situation, such as raw material cost, reaction conditions, product requirements, etc., to achieve the purpose of synthesis and obtain the required 6-methoxy-2-aminobenzothiazole.

6-Methoxy-2-aminobenzothiazole is an organic compound. It has unique physical and chemical properties and is very important in the chemical and pharmaceutical fields.
When it comes to physical properties, under normal conditions, 6-methoxy-2-aminobenzothiazole is mostly solid, and the appearance may be white to pale yellow crystalline powder. The melting point is about 120-124 ° C. This characteristic can help to identify the purity of the substance by means of melting point determination. In addition, its solubility also has characteristics. It is slightly soluble in water, but soluble in common organic solvents such as ethanol, acetone, dichloromethane, etc. This solubility is convenient for selecting suitable solvents for reaction and separation in organic synthesis operations.
In terms of chemical properties, the amino group of 6-methoxy-2-aminobenzothiazole is basic and can react with acids to form corresponding salts. For example, by reacting with hydrochloric acid, hydrochloride salts can be obtained. This reaction helps to improve drug solubility and stability during drug preparation. At the same time, the benzothiazole ring system endows it with certain aromatics and conjugated structures, so that the compound has certain electron delocalization properties and can participate in various electrophilic substitution reactions. For example, under appropriate conditions, halogenation reactions, nitrification reactions, etc. can occur, and other functional groups can be introduced into the benzothiazole ring, thereby expanding its application in organic synthesis. Moreover, the methoxy group as the power supply group will affect the electron cloud distribution of the benzothiazole ring, changing the reactivity and selectivity on the ring. This electronic effect should be fully considered in the synthesis design.

6-Methoxy-2-aminobenzothiazole is in the market, and its price range is difficult to determine. The price varies with many factors, such as the supply and demand of the market, the cost of production, the quality of the product, the quantity purchased, and the seller's policy.
Looking at the past "Tiangong Kaiwu", although the special price of this product is not involved, the analysis of the production and flow of the product can also be learned from the price. If the supply of the product is wider than the demand, the price will decline; if the supply is less than the demand, the price may rise.
As far as 6-methoxy-2-aminobenzothiazole is concerned, the cost of production involves the purchase of raw materials, the process of construction, and the loss of equipment. If the raw materials are rare and expensive, the price must be high. The quality is high, and the regular price is not cheap. And if the purchase quantity is large, the seller may give a discount, and the price may drop.
Today in the market, the price may vary depending on the region. In places with close production and sufficient supply, the price may be lower; in remote places with less supply, the price may be higher. However, if you want to know the exact price, you need to consult the suppliers, traders, or check the recent transaction price on the chemical raw materials trading platform before you can get a more accurate price range. Or from hundreds to thousands of yuan per kilogram, it is difficult to generalize.

6-Methoxy-2-aminobenzothiazole is one of the organic compounds, which is widely used in medicine, pesticides and other fields. There are many manufacturers, all over the world.
In China, there are many manufacturers involved in the production of this compound. Such as XX Chemical Co., Ltd., which is committed to the output of 6-methoxy-2-aminobenzothiazole with excellent technology and strict quality control. The factory focuses a lot on technology research and development, and strives for excellent product quality to meet the diverse needs of the market.
Furthermore, XX Technology joint stock company is also an important producer of this compound. With its profound scientific research heritage and advanced production equipment, the 6-methoxy-2-aminobenzothiazole produced is of high quality and sufficient quantity, and is sold domestically.
Overseas countries, there are also many such manufacturers. Such as Europe and the United States, there are several chemical companies, focusing on the manufacture of this compound. Its advanced technology, large-scale production, products are exported to the world, and it has a place in the international market.
Overall, 6-methoxy-2-aminobenzothiazole manufacturers are all over the world. Each factory uses its own advantages to supply this important compound to the market and promote the prosperity and development of related industries.