6 Hydroxy 1 3 Benzothiazole 2 Carbonitrile
quinoline thiophene imidazole thiazole

6-Hydroxy-1,3-benzothiazole-2-carbonitrile

    Specifications

    HS Code

    745795

    Chemical Formula C8H4N2OS
    Molecular Weight 176.195 g/mol
    Appearance Solid (predicted)
    Boiling Point 440.2°C at 760 mmHg (predicted)
    Melting Point 233 - 235 °C
    Flash Point 220°C (predicted)
    Density 1.522 g/cm³ (predicted)
    Logp 1.51 (predicted)
    Solubility Soluble in DMSO (Slightly), Methanol (Slightly)
    Pka 9.54±0.20 (Predicted)

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    General Information
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    Frequently Asked Questions

    As a leading 6-Hydroxy-1,3-benzothiazole-2-carbonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 6-Hydroxy-1, 3-benzothiazole-2-carbonitrile?
    6-Hydroxy-1,3-benzothiazole-2-formonitrile has a wide range of uses in the field of organic synthesis. It can be used as a key intermediate to prepare a variety of biologically active compounds.
    First, in the field of pharmaceutical chemistry, through structural modification and derivatization of this compound, new drug molecules can be created. Because of its specific chemical structure, or biological activities such as antibacterial, anti-inflammatory, and anti-tumor, it can interact with specific targets in organisms to regulate physiological processes and then exert the effect of treating diseases.
    Second, in the field of materials science, 6-hydroxy-1,3-benzothiazole-2-formonitrile can participate in the synthesis of functional materials. For example, the synthesis of materials with special optical and electrical properties is used in the field of optoelectronics, such as organic Light Emitting Diode (OLED), solar cells, etc. Its structural characteristics endow the material with unique properties and improve the efficiency of the device.
    Furthermore, in the field of agricultural chemistry, new pesticides can be developed on this basis. Or it has inhibitory or killing effects on pests, bacteria, etc., providing a new way for pest control in agricultural production, helping to improve crop yield and quality, and ensuring the sustainable development of agriculture.
    It has shown important application value in many fields such as organic synthesis, drug research and development, material preparation, and agricultural chemistry, providing key chemical raw materials and research bases for the development of various fields.
    6-Hydroxy-1, what are the physical properties of 3-benzothiazole-2-carbonitrile
    6-Hydroxy-1,3-benzothiazole-2-formonitrile, this is an organic compound. Its physical properties are quite important, and it is related to many chemical and practical application fields.
    First, the appearance of this compound is usually powdery, and the color may be white to light yellow. This appearance characteristic can be used as an important basis for the identification and preliminary judgment of its purity. If the color deviation is large or the appearance is abnormal, or it implies that it contains impurities.
    When it comes to the melting point, it has a specific melting point range. Accurate determination of the melting point can assist in the identification of the compound. The melting point of the substance with different purity and structure may vary. By measuring the melting point, its purity and molecular structure stability can be inferred.
    Solubility is also a key physical property. In organic solvents, such as common ethanol, dichloromethane, etc., it may have a certain solubility. This property is of great significance in organic synthesis, separation and purification, and drug research and development. In the synthesis reaction, a suitable solvent needs to be selected to fully dissolve the reactants to promote the smooth progress of the reaction. In the separation and purification process, high-purity products can be obtained by extraction, recrystallization and other means according to their solubility differences.
    In addition, the density of the compound cannot be ignored. Although the specific density value varies depending on the measurement conditions, the density information plays a key role in calculating the proportion of reactant materials and determining the yield of the product. In industrial production, accurately knowing the density helps to control the scale of the reaction and product quality.
    To sum up, the physical properties of 6-hydroxy-1,3-benzothiazole-2-formonitrile, such as appearance, melting point, solubility and density, are of great value to its chemical research and practical application. Researchers need to accurately grasp them in order to better carry out related work.
    What is the chemical synthesis method of 6-Hydroxy-1,3-benzothiazole-2-carbonitrile
    The chemical synthesis of 6-hydroxy-1,3-benzothiazole-2-formonitrile has attracted much attention in the field of organic synthesis. In the past, many researchers have focused on this and gradually developed several available methods.
    First, o-aminothiophenol and cyanoacetate ethyl ester are used as starting materials, which can be obtained through several steps of condensation and cyclization. First, o-aminothiophenol and cyanoacetate ethyl ester are condensed under suitable catalyst and reaction conditions to form an intermediate product. In this step, attention should be paid to the type and dosage of catalyst, as well as the control of reaction temperature and time. Commonly used catalysts include a certain type of basic compound. Under mild temperatures and after several times of reaction, the intermediate product can be successfully formed. Then, under the action of a specific cyclization agent, the intermediate product is cyclized to form the target product 6-hydroxy-1,3-benzothiazole-2-formonitrile. In this cyclization step, the activity and selectivity of the cyclization reagent are extremely critical, and the reaction parameters need to be carefully adjusted to obtain a product with higher yield and purity.
    Second, there is also a synthesis path using 2-amino-6-hydroxybenzothiazole and halogenated acetonitrile as raw materials. 2-Amino-6-hydroxybenzothiazole and haloacetonitrile were placed in a suitable solvent, and a suitable base was added as an acid binding agent. During the reaction, the activity of the halogen atom of haloacetonitrile affects the reaction process, and the strength and dosage of the base also have a significant effect on the reaction. At a suitable temperature and reaction time, the halogen atom of haloacetonitrile reacts with the amino group of 2-amino-6-hydroxybenzothiazole to form 6-hydroxy-1,3-benzothiazole-2-formonitrile.
    These two are common methods for synthesizing 6-hydroxy-1,3-benzothiazole-2-formonitrile, each with its own advantages and disadvantages. In practical applications, the appropriate synthesis method needs to be weighed according to many factors such as the availability of raw materials, cost, and difficulty in controlling reaction conditions.
    What is the price range of 6-Hydroxy-1,3-benzothiazole-2-carbonitrile in the market?
    I have not heard the exact price of 6-hydroxy-1,3-benzothiazole-2-formonitrile in the market. The price of these substances may vary due to differences in quality, supply and demand, source and purchase quantity. And the price of chemical raw materials often fluctuates with changes in market conditions, and it is difficult to have a constant price.
    If you want to know the price, you can consult the supplier of chemical raw materials, or visit the relevant chemical product trading platform. On these platforms, you can check a number of prices offered to get a rough idea. Or refer to the price of past transactions, but it is only for reference, and it is difficult to make a conclusion. < Br >
    The transaction of chemical raw materials involves many qualifications and procedures, and the buyer needs to follow the regulations. It is also important to pay attention to its safety and use it in accordance with safety regulations. Although the exact price cannot be specified, the approximate range of the price may be obtained by following this route.
    6-Hydroxy-1, what are the storage conditions for 3-benzothiazole-2-carbonitrile?
    6-Hydroxy-1,3-benzothiazole-2-formonitrile is a special chemical substance. Its storage conditions are crucial to the stability and quality of this substance.
    This substance should be stored in a cool place away from direct sunlight. Cover the heat and light of sunlight, which can cause its chemical structure to change and damage its properties. And it should be a dry place. If it is in a humid environment, it is easy for water vapor to interact with it, or cause reactions such as hydrolysis, which will damage its original state.
    Furthermore, the storage place needs to be well ventilated. If the air is not smooth, the accumulated volatile gas may cause the local concentration to be too high, which increases the risk of combustion and explosion, and is not conducive to its long-term preservation. It should also be stored separately with oxidizing agents, acids, bases, etc., to avoid interaction. These numbers can all chemically react with 6-hydroxy-1,3-benzothiazole-2-formonitrile, causing it to deteriorate.
    In the choice of container, it should not be ignored. A sealed container must be used to prevent it from excessive contact with the outside air, and the material should not react with it to maintain its chemical stability. Only when all conditions are ready can 6-hydroxy-1,3-benzothiazole-2-formonitrile be properly stored and used to its fullest extent.