6 Chloro 2 Methylpyrimidin 4 Ylamino N 2 Chloro 6 Methylphenyl Thiazole 5 Carboxamide
Quinoline Thiophene Imidazole Thiazole
(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
Chemical Name (6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
Molecular Formula C16H13Cl2N5OS
Molecular Weight 394.27 g/mol
Appearance Typically a solid (description may vary based on purity and preparation)
Melting Point Data may vary, requires experimental determination
Boiling Point Data may vary, requires experimental determination
Solubility Solubility characteristics depend on solvents; likely low solubility in water, more soluble in organic solvents
Pka Data may vary, requires experimental determination
Logp Value depends on experimental determination, indicates lipophilicity
Chemical Stability Stability can be affected by factors like heat, light, and humidity
FAQ

What is the chemical structure of (6-Chloro-2-methylpyrimidin-4-ylamino) -N- (2-chloro-6-methylphenyl) thiazole-5-carboxamide?

(6-Chloro-2-methylpyrimidine-4-ylamino) -N - (2-chloro-6-methylphenyl) thiazole-5-formamide, this is an organic compound. Its chemical structure is quite complex, composed of three parts: pyrimidine, thiazole and benzene ring.

Bearing the brunt, the pyrimidine ring part is added with a chlorine atom at the 6th position, a methyl group at the 2nd position, and an amino group at the 4th position. As a key linking group, the amino group can form covalent bonds with other parts, highlighting its key role in the molecular structure.

One side of the thiazole ring is connected to the formamide group, which gives the molecule specific chemical activity and reaction characteristics. The other side is connected to the pyrimidine ring through the amino group to build the core skeleton of the molecule.

Furthermore, the benzene ring is connected with a chlorine atom and a methyl at the 2nd and 6th positions, respectively. The existence of the benzene ring greatly affects the electron cloud distribution and spatial configuration of the molecule, which in turn affects the physical and chemical properties of the whole molecule. This benzene ring is connected to the N- (2-chloro-6-methylphenyl) of the thiazole ring, and together shape the overall structure of the molecule.

The chemical structure of this compound is formed by the ingenious splicing of these three parts, and each part interacts and influences each other, endowing the compound with unique chemical and physical properties, which may hold potential application value in the fields of organic synthesis, medicinal chemistry, etc.

(6-Chloro-2-methylpyrimidin-4-ylamino) -N- (2-chloro-6-methylphenyl) What are the main uses of thiazole-5-carboxamide?

(6-Chloro-2-methylpyrimidine-4-ylamino) -N - (2-chloro-6-methylphenyl) thiazole-5-formamide This substance has its own uses in agriculture, medicine, and chemical industries.

In the field of agriculture, it can be used as a pesticide. Such compounds may have insecticidal and bactericidal properties, and can control field pests and diseases. With exquisite chemical structure, it acts on the physiological mechanism of bugs and fungi. Or interfere with the metabolic pathway of bugs and fungi, or disrupt their cellular structure, making it difficult for bugs and fungi to survive and multiply, maintaining the health of crops and increasing the yield of grain. < Br >
In the pharmaceutical industry, it may be a key intermediate for the research and development of new drugs. Designed and modified by chemists, or with unique pharmacological activity. It can target specific disease targets, or regulate human physiological functions, or inhibit the growth of diseased cells. After complex tests and optimization, it is expected to become a good medicine for the treatment of difficult diseases, and bring hope for recovery to patients.

In the chemical industry, it is an important raw material for organic synthesis. With its unique chemical properties, it reacts with other compounds in a series to generate a variety of high value-added chemicals. It can be used to manufacture special materials, functional additives, etc., to expand the application range of chemical products, promote the progress of chemical technology, and inject new vitality into industrial development.

In summary, (6-chloro-2-methylpyrimidine-4-ylamino) -N - (2-chloro-6-methylphenyl) thiazole-5-formamide is a chemical substance, but it plays a key role in many industries and brings many benefits to human life and production.

What are the synthesis methods of (6-Chloro-2-methylpyrimidin-4-ylamino) -N- (2-chloro-6-methylphenyl) thiazole-5-carboxamide?

The synthesis method of (6-chloro-2-methylpyrimidine-4-ylamino) -N - (2-chloro-6-methylphenyl) thiazole-5-formamide is particularly critical, which is related to the acquisition and application of this compound.

To synthesize this compound, one method can be obtained by the interaction between the compound containing the pyrimidine structure and the derivative containing the thiazole structure. Take the appropriate 6-chloro-2-methylpyrimidine-4-amine and prepare it carefully to ensure its purity and activity. At the same time, N- (2-chloro-6-methylphenyl) thiazole-5-formyl chloride is prepared. This step requires careful operation and control of reaction conditions, such as temperature, solvent selection, etc. When both are ready, in a suitable reaction system, under the action of catalysts, they are allowed to react with each other, and the synthesis of the target product is achieved through the formation of amide bonds.

Another way is to start from the starting materials for the construction of pyrimidine and thiazole rings, and gradually build the target molecule through multi-step reactions. First, a suitable halogenated aromatic hydrocarbon and a nitrogen-containing heterocyclic compound are used as the starting point, and nucleophilic substitution and other reactions are used to build the pyrimidine ring. Then, through a specific reaction step, the thiazole ring is introduced and the connection with the phenyl group is completed, resulting in (6-chloro-2-methylpyrimidine-4-ylamino) -N - (2-chloro-6-methylphenyl) thiazole-5-formamide.

Each step requires precise control of conditions, such as reaction temperature, reaction time, ratio of reactants, and choice of solvent and catalyst, which will have a significant impact on the yield and purity of the product. Only by careful operation and attention to many details can this compound be synthesized efficiently and with high quality.

(6-Chloro-2-methylpyrimidin-4-ylamino) -N- (2-chloro-6-methylphenyl) How safe is the thiazole-5-carboxamide?

(6-Chloro-2-methylpyrimidine-4-ylamino) -N - (2-chloro-6-methylphenyl) thiazole-5-formamide, this is a complex organic compound. However, its safety is difficult to sum up, and it needs to be investigated in detail in many aspects.

First describe its chemical structure. The compound contains heterocyclic structures such as pyrimidine and thiazole, which are common in many organic compounds or have specific biological activities. However, the existence of heterocyclic rings may also cause its chemical activity, or interact with biological macromolecules in vivo, leading to adverse reactions.

Second Discussion on Toxicology. Due to the absence of specific toxicological research data, it can only be speculated from compounds with similar structures. Organic compounds containing chlorine substituents, some of which may have certain toxicity, can affect the metabolism of organisms and interfere with cell functions. Chlorine atoms in the body or participate in chemical reactions, generate active intermediates, and damage important biomolecules such as cellular proteins and nucleic acids.

Look at the environmental impact. If this compound is released in the environment, its complex structure may be difficult to degrade and long-term residual. or enriched through the food chain, posing a potential threat to the ecosystem. However, its specific environmental behavior, such as migration, transformation and fate in soil, water and air, all require experimental data support.

And human exposure pathways. If exposed in industrial production, it can cause human exposure through inhalation, skin contact or accidental ingestion. Inhalation of dust or vapor containing this compound can damage the respiratory system; skin contact or allergic, irritating reactions; accidental ingestion may cause digestive system and systemic toxicity.

In summary, the safety of (6-chloro-2-methylpyrimidine-4-ylamino) -N - (2-chloro-6-methylphenyl) thiazole-5-formamide remains unknown, and comprehensive and in-depth studies are required, such as toxicological experiments and environmental behavior studies, in order to accurately evaluate its potential impact on human health and the environment.

(6-Chloro-2-methylpyrimidin-4-ylamino) -N- (2-chloro-6-methylphenyl) What is the market outlook for thiazole-5-carboxamide?

(6-Chloro-2-methylpyrimidine-4-ylamino) -N - (2-chloro-6-methylphenyl) thiazole-5-formamide, this is a specific organic compound. Its market prospect is related to multiple factors, try to analyze it for you.

From the perspective of the agricultural field, many compounds with such structures are often used for pesticide research and development, or have insecticidal, bactericidal and herbicidal activities. If this compound has unique effects on pest control, can accurately respond to specific pests and diseases, and is environmentally friendly and has low residues, it will have a wide world in the pesticide market. Nowadays, with the rise of green agriculture, the demand for high-efficiency and low-toxicity pesticides is on the rise. If it fits this trend, it will definitely be favored by farmers, and the market potential is unlimited.

In the field of medicine, some compounds containing pyrimidine and thiazole structures are biologically active, or can be used as drug lead compounds. If in-depth research shows that it has therapeutic effects on specific diseases, such as anti-cancer, antibacterial, etc., it is expected to be developed into new drugs after clinical trials. Once successful, its market value is incalculable, because the demand for innovative drugs in the pharmaceutical market has always been strong.

However, its market expansion also faces challenges. If the synthesis process is complex, the cost will be high, which will affect the market competitiveness. And the pesticide and pharmaceutical industries are strictly regulated, and products need to go through many tests and approvals before they can be listed, which is time-consuming and laborious.

In summary, (6-chloro-2-methylpyrimidine-4-ylamino) -N- (2-chloro-6-methylphenyl) thiazole-5-formamide can overcome the synthesis and regulatory problems and give full play to its own activity advantages. It has a bright future in the pesticide and pharmaceutical markets, but it needs to deal with many tests in the process before it can emerge in the market.