5 Thiazolecarbonyl Chloride 4 Methyl 2 Phenyl
quinoline thiophene imidazole thiazole

5-thiazolecarbonyl chloride, 4-methyl-2-phenyl-

    Specifications

    HS Code

    414247

    Chemical Formula C11H8ClNO2S
    Molecular Weight 253.706

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    General Information
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    Frequently Asked Questions

    As a leading 5-thiazolecarbonyl chloride, 4-methyl-2-phenyl- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 5-thiazolyl chloride, 4-methyl-2-phenyl-?
    5-Pentenyl ether, 4-methyl-2-phenyl-The physical properties of this substance are as follows:
    Its properties, at room temperature and pressure, are mostly colorless to light yellow transparent liquids. The reason why it presents such a color and state is determined by the arrangement and interaction of atoms in its molecular structure. The unsaturated structure of the pentenyl group and the existence of the ether group give it a unique aggregation state and optical properties.
    Regarding the odor, it has a weak and special ether odor. This is due to the presence of ether bonds in the molecule. The chemical properties of the ether bonds make the substance interact with the nasal olfactory receptors during the volatilization process, resulting in this specific odor sensation. < Br >
    Its boiling point is within a certain range, which varies depending on the specific structural details and intermolecular forces. Generally speaking, the unsaturation and side chain structure of pentenyl groups will reduce the van der Waals force between molecules. Compared with straight-chain saturated ethers, the boiling point will be reduced. The introduction of phenyl groups, due to its large π bond structure, increases the rigidity of the molecule and the delocalization of the electron cloud, and will increase the boiling point to a certain extent. Under the combined action, its boiling point has a specific value.
    In terms of solubility, it can be soluble in a variety of organic solvents, such as ethanol, ether, chloroform, etc. This is based on the principle of similar phase dissolution. The molecules of this substance have certain hydrophobicity, similar to the intermolecular force of organic solvents, and can be interspersed and mixed with each other, thus showing good solubility. The solubility in water is low, because the water molecules form a relatively tight structure through hydrogen bonds, and it is difficult for the molecules of this substance to form effective interactions with water molecules, so it is not easily soluble in water.
    The density also has a specific value, which is smaller than the density of water. This is because its molecules are dominated by carbon and hydrogen, the atomic mass is relatively small, and the accumulation of molecular structures makes the mass per unit volume lower than that of water, so it will float on the surface when mixed with water.
    What are the chemical properties of 5-thiazolyl chloride, 4-methyl-2-phenyl?
    The chemical properties of 5-pentene acetic anhydride, 4-methyl-2-phenyl-are:
    This compound has the property of addition reaction due to carbon-carbon double bonds. In case of bromine water, it can be added to make bromine water fade. This is a typical reaction of double bonds, and bromine atoms are added to the carbon at both ends of the double bond. It can also react with hydrogen under the action of a catalyst to generate saturated hydrocarbon derivatives. This is the method of preparing saturated compounds. And it can be added to hydrogen halide. According to Markov's rule, hydrogen is added to the carbon containing more hydrogen double bonds, and halogen atoms are added to those containing less hydrogen. This reaction can be used to introduce halogen atoms.
    Its acid anhydride structure also has unique properties. In contact with water, it can be hydrolyzed to form corresponding carboxylic acids, which is the way to prepare carboxylic acids. Reaction with alcohol can occur alcoholysis to form esters and carboxylic acids. This is a method for preparing esters and is commonly used in organic synthesis.
    Because it contains a benzene ring, it has properties similar to benzene. Substitution reactions can occur, such as halogenation with halogens under catalysts, where halogen atoms replace hydrogen atoms on the benzene ring. This is a method for introducing halogen atoms into the benzene ring. Nitrification reactions can also occur. Under the action of concentrated nitric acid and concentrated sulfuric acid, nitro groups are introduced into the benzene ring, and the product is an important intermediate in organic synthesis.
    Methyl is connected to phenyl group, affected by the phenyl ring, the methyl activity changes, and can be oxidized under specific conditions to form carboxyl-containing compounds. This reaction is used for functional group conversion in organic synthesis.
    In summary, 5-pentene acetic anhydride, 4-methyl-2-phenyl-because contain a variety of functional groups, have diverse chemical properties, and have many applications in the field of organic synthesis.
    What are the common synthesis methods of 5-thiazolyl chloride, 4-methyl-2-phenyl?
    To prepare 5-aldehyde-pyridinonitrile, 4-methyl-2-benzyl-nitrile, common synthesis methods are as follows:
    First, a suitable pyridine derivative is used as the starting material. Pyridine compounds containing suitable substituents can be first found, and halogenation reactions can be carried out to introduce halogen atoms at specific positions on the pyridine ring. This halogenation reaction requires careful selection of reaction conditions and halogenating reagents, such as in the presence of suitable solvents, temperatures and catalysts, so that the reaction can occur smoothly. Subsequently, metal-organic reagents, such as Grignard reagents or organolithium reagents, are used to react with halogenated pyridine derivatives. This step can achieve the construction of carbon-carbon bonds and introduce the desired hydrocarbon substituents. During the reaction, factors such as the nature of the solvent, the reaction temperature, and the equivalent of the reagent all have important effects on the selectivity and yield of the reaction.
    Second, for the introduction of aldehyde groups, a mild oxidation reaction can be used. When the pyridine derivative has suitable substituents, a specific oxidant can be selected, such as manganese dioxide or Dess-Martin reagent, to oxidize the specific hydrocarbon group to aldehyde group under appropriate reaction conditions. This oxidation reaction requires precise control of the reaction conditions to ensure that only the target group is selectively oxidized without affecting the structure of pyridine and other substituents.
    Furthermore, there are various strategies for the introduction of nitrile groups. Nitrile groups can be introduced into the pyridine ring by nucleophilic substitution of halogenated pyridine derivatives with cyanide reagents such as potassium cyanide or sodium cyanide in the presence of a phase transfer catalyst. Alternatively, the introduction of nitrile groups can also be achieved by using amino-containing pyridine derivatives as raw materials through diazotization and then reacting with reagents such as cuprous cyanide. In the
    synthesis process, the products of each step of the reaction need to be separated and purified. The commonly used methods include column chromatography, recrystallization, etc., to ensure the purity of the products in each step, and then provide high-quality raw materials for the next reaction. Finally, the effective synthesis of 5-aldehyde-pyridinonitrile and 4-methyl-2-benzyl-nitrile is achieved.
    What are the main applications of 5-thiazolyl chloride, 4-methyl-2-phenyl?
    Ethyl 5-pentenoate, 4-methyl-2-furyl-is mainly used in the fields of flavors, food additives, and pharmaceutical chemicals.
    In the field of fragrances, this compound can add unique flavor to various flavors with its unique odor characteristics. In the field of food additives, it can add special flavor to food, enhance the smell and taste experience of food, and is commonly found in the production of beverages, candies, baked goods, etc., making it emit an attractive aroma and increase appetite. In the field of pharmaceutical and chemical industry, it may be an important organic synthesis intermediate for the preparation of drug molecules with specific physiological activities. By virtue of its structural characteristics, it participates in chemical reactions, and is chemically modified and converted to generate compounds with medicinal value. It plays a key role in drug research and development and production.
    For example, when blending floral flavors, ethyl 5-valproate can simulate the freshness and elegance of natural floral aromas, and cooperate with other fragrance ingredients to create a realistic floral atmosphere. In the food industry, adding a small amount of this compound to fruit juice beverages can enhance the fruity flavor of the beverage, making it more mellow and full. In the pharmaceutical and chemical synthesis process, 4-methyl-2-furanyl, as a key structural unit, participates in the construction of complex drug molecular structures, helping to create new drugs to deal with various diseases.
    5-Thiazolyl chloride, 4-methyl-2-phenyl - What are the precautions during storage and transportation?
    5-Bromovaleronitrile, 4-methyl-2-phenyl - There are several precautions to be paid attention to during storage and transportation.
    First, about storage. Both need to be stored in a cool, dry and well-ventilated place. Due to the nature of 5-bromovaleronitrile and 4-methyl-2-phenyl or more active, high temperature and humid environment can easily cause chemical reactions to cause deterioration. And it should be kept away from fire and heat sources. In case of open flame, hot topic or risk of combustion and explosion. In addition, it needs to be stored separately from oxidants, acids, bases, etc., and cannot be mixed. Contact between 5-bromovaleronitrile and 4-methyl-2-phenyl with the above substances may trigger violent chemical reactions and endanger safety.
    Second, it is related to transportation. When transporting, make sure that the container is well sealed to prevent leakage. If 5-bromovaleronitrile or 4-methyl-2-phenyl leaks, it will not only cause material loss, but also be toxic and irritating, or pose a hazard to the environment and human health. Transportation vehicles should also be equipped with corresponding varieties and quantities of fire fighting equipment and leakage emergency treatment equipment for emergencies. During transportation, pay attention to smooth driving, avoid bumps and collisions, and prevent leakage due to damage to the container. At the same time, transportation personnel need to undergo professional training, be familiar with the dangerous characteristics and emergency treatment methods of 5-bromovaleronitrile and 4-methyl-2-phenyl, and pay close attention to the condition of the goods during transportation. If any abnormalities are detected, they will be properly disposed of immediately.