5 Methoxybenzothiazole 2 Thiol
quinoline thiophene imidazole thiazole

5-Methoxybenzothiazole-2-thiol

    Specifications

    HS Code

    685357

    Chemical Formula C8H7NO2S2
    Molar Mass 213.28 g/mol
    Appearance Solid (usually)
    Solubility In Water Low (due to non - polar nature of benzothiazole ring)
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Odor Characteristic sulfur - containing compound odor

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    General Information
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    Frequently Asked Questions

    As a leading 5-Methoxybenzothiazole-2-thiol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemistry of 5-Methoxybenzothiazole-2-thiol?
    5-Methoxybenzothiazole-2-mercaptan is an organic compound. It has unique chemical properties and shows its function in many fields.
    Looking at its structure, benzothiazole ring is connected to methoxy group and thiol group. Methoxy group has electron supply effect, which can affect the electron cloud density and reactivity of molecules. Mercaptan group is active and easy to participate in a variety of chemical reactions.
    In terms of its chemical properties, 5-methoxybenzothiazole-2-mercaptan is acidic. Due to the strong electronegativity of the sulfur atom of the thiol group and its connection to the hydrogen atom, the hydrogen atom is easily dissociated in the form of protons, showing acidic characteristics. This acidity allows it to neutralize with bases to form corresponding salts.
    Furthermore, the thiol group of the compound has strong nucleophilicity. The nucleophilicity stems from the presence of lone pairs of electrons on the sulfur atom, which makes it easy to attack electron-deficient atoms or groups. In this way, 5-methoxybenzothiazole-2-thiol can participate in nucleophilic substitution reactions, such as reacting with halogenated hydrocarbons, and the thiol group replaces the halogen atom to form a new organosulfur compound.
    In addition, the conjugated system of the benzothiazole ring endows it with certain stability and optical properties. This conjugated system can absorb specific wavelengths of light and exhibit corresponding colors, which may have applications in the field of optical materials.
    5-methoxybenzothiazole-2-thiol has acidic and nucleophilic chemical properties due to the characteristics of methoxy and thiol groups. The conjugated system of its benzothiazole ring also affects its stability and optical properties, and has potential application value in organic synthesis, materials science and other fields.
    What are the common uses of 5-Methoxybenzothiazole-2-thiol?
    5-Methoxybenzothiazole-2-mercaptan is commonly used in a wide range of ways. In the field of chemical synthesis, it is often used as a key intermediate. Because of its special structure and activity, it can undergo various chemical reactions and interact with various reagents to prepare other sulfur-containing heterocyclic compounds. Such compounds have important uses in the fields of medicine, pesticides, and materials science.
    In pharmaceutical research and development, compounds derived from 5-methoxybenzothiazole-2-mercaptan may have unique biological activities, such as antibacterial, antiviral, and antitumor properties, providing the possibility for the creation of new drugs. In terms of pesticides, the derived products can be used as insecticides and fungicides, which have positive effects on crop disease and pest control.
    In the field of materials science, materials synthesized from this substance may have special electrical and optical properties, and can be applied to optoelectronic devices, sensors, etc. In addition, in the study of organic synthetic chemistry, 5-methoxybenzothiazole-2-thiol can participate in the construction of complex organic molecular structures, enabling chemists to explore novel synthesis methods and strategies, and expand the variety and properties of organic compounds.
    What are 5-Methoxybenzothiazole-2-thiol synthesis methods?
    The synthesis method of 5-methoxy-benzothiazole-2-thiol has been known for a long time, and is described in detail below.
    First take an appropriate amount of 5-methoxy-2-halobenzothiazole, halogenated, chlorinated or brominated. Place it in a reactor and add an appropriate amount of sodium hydrosulfide or thiourea and other sulfur-containing reagents. Dissolve it with an appropriate organic solvent, such as dimethyl sulfoxide, N, N-dimethylformamide, etc. Such solvents can fully mix the reactants and promote the reaction. < Br >
    Heat up to a suitable temperature, generally between 50 and 100 degrees Celsius, and fine-tune according to the specific conditions of the reaction. This temperature range allows the reaction rate to neither increase the side reactions too quickly, nor be too slow and time-consuming. Maintain this temperature and stir the reaction for several hours. During this period, closely observe the reaction process, which can be monitored by thin-layer chromatography and other means.
    When the reaction is completed, cool the reaction solution to room temperature. Thereafter, adjust the pH value of an appropriate acid, such as hydrochloric acid, to an acidic level, so that the product can be precipitated. The precipitated product can be obtained by filtration, washing, and removing its impurities. < Br >
    Then recrystallization is carried out in a suitable solvent, such as ethanol, ethyl acetate, etc., to further purify the product. After this step, high purity 5-methoxybenzothiazole-2-thiol can be obtained.
    Another method, using 5-methoxybenzothiazole as the starting material, first through oxidation reaction, the nitrogen atom on the benzothiazole ring is oxidized to the corresponding oxide. After reacting with sulfur reagents, such as Lawesson reagent, at appropriate temperature and solvent, the target product can be obtained. This process requires fine control of the reaction conditions. The degree of oxidation steps, the temperature and time of reaction with sulfur reagents have a significant impact on the yield and purity of the product. After subsequent separation and purification steps, pure 5-methoxybenzothiazole-2-thiol can also be obtained.
    5-Methoxybenzothiazole-2-thiol What are the precautions during storage and transportation?
    5-Methoxybenzothiazole-2-mercaptan is a special chemical substance, and there are indeed many key matters that need careful attention during storage and transportation.
    Selection of the first storage environment. This substance needs to be stored in a cool, dry and well-ventilated place. Due to high temperature and humidity, it is easy to cause chemical reactions and damage the quality. For example, if the summer temperature is high, if the storage place does not have suitable cooling facilities, the temperature is too high, or it may cause decomposition; or if there is no moisture-proof means in the south, water vapor intrusion will also affect its chemical stability.
    Furthermore, the material of the storage container is also crucial. Containers that are compatible with 5-methoxybenzothiazole-2-thiol should be selected, such as glass, certain plastic materials, etc. Metal containers may deteriorate due to chemical reactions with the substance. For example, some active metal containers may react with chemical groups in them to change their chemical structure.
    When transporting, safety protection is a top priority. Be sure to ensure that the packaging is tight to prevent leakage. Transportation vehicles also need to be equipped with appropriate emergency treatment equipment in case of leakage and other unexpected situations, so that they can respond in time. And during transportation, avoid severe vibration and collision. Excessive vibration or collision, or damage to the packaging, can cause the substance to leak and cause safety hazards.
    In addition, relevant regulations and standards must be strictly followed whether it is storage or transportation. Operators should also receive professional training to be familiar with the properties of the substance and how to deal with emergencies, so as to ensure smooth storage and transportation and avoid safety accidents.
    What is the market price of 5-Methoxybenzothiazole-2-thiol?
    What you are asking about is the market price of 5-methoxybenzothiazole-2-mercaptan. However, the price of this chemical often varies for a variety of reasons, and it is difficult to determine the exact number.
    First, the purity of this product has a great impact on its price. If the purity is extremely high and almost flawless, its price will be high; if it contains impurities and the purity is slightly inferior, the price will drop. For example, in the field of fine chemical pharmaceuticals, those who need high purity are willing to pay a high price to ensure the quality of the product.
    Second, the purchase quantity also affects its price. If you buy in bulk, the seller may give a discount due to economies of scale, and the unit price will be lower; if you buy in small quantities, it is only for laboratory research, and the price may be higher.
    Third, the state of market supply and demand is also the key. If there are many applicants, the supply will be tight, and the price will rise; if the supply exceeds the demand, the merchant will sell his goods, or reduce the price to promote the transaction.
    Fourth, the prices are different in different regions, coupled with the different transportation costs, which also lead to different prices. In prosperous cities, the price is high; near the origin, the price may be slightly lower due to the saving of long-distance freight.
    In my opinion, if you want to know the exact price, you can consult the chemical raw material supplier, chemical product trading platform, or related industry personnel. In this way, you can obtain more accurate price information to meet your needs.