5-Hydroxymethylthiazole

5-Hydroxymethylthiazole has many main uses. In the field of medicine, it is a key intermediate. Through a series of delicate chemical reactions, various drugs can be prepared. For example, antibacterial drugs, 5-hydroxymethylthiazole can be converted appropriately, or can generate ingredients with antibacterial activity, which has the effect of inhibiting and killing many bacteria, protecting human health and preventing the disturbance of pathogens.
In the chemical industry, it is also an important place. It can be used as a raw material for synthesizing special functional materials. Through a specific process, polymerization with other compounds can produce polymer materials with excellent performance, or with good stability, corrosion resistance, etc., which are used in many high-end manufacturing fields, such as aerospace material-assisted synthesis, to make the material more suitable for harsh environmental needs.
In agriculture, 5-hydroxymethylthiazole may also contribute. Or can participate in the synthesis of new pesticides, which may have specific repellent or poisoning effects on pests, and are environmentally friendly, reduce the adverse impact on ecology, help the green development of agriculture, and ensure crop yield and quality. In short, 5-hydroxymethylthiazole has important uses in medicine, chemical industry, agriculture and other fields, promoting the progress and development of various industries.

5-Hydroxymethylthiazole is an organic compound. Its physical properties are crucial and related to applications in many fields.
Looking at its appearance, under normal conditions, 5-hydroxymethylthiazole is mostly white to light yellow crystalline powder, which is easy to identify and operate. Its color is pure, and the particles are delicate and uniform, laying a good foundation for subsequent use.
When it comes to melting point, the melting point of 5-hydroxymethylthiazole is within a specific range. The precise melting point value is of great significance for determining its purity and stability. The control of the precise melting point range ensures that the properties of the compound are stable in different process steps and will not undergo qualitative changes due to temperature fluctuations.
Solubility is also an important physical property. 5-hydroxymethylthiazole exhibits different solubility characteristics in specific solvents. In common organic solvents such as ethanol and acetone, it has good solubility and can be quickly and uniformly dispersed to form a uniform solution, which is conducive to participating in various chemical reactions. In water, the solubility is relatively limited, and this difference determines its application direction in different systems.
Furthermore, the smell of 5-hydroxymethylthiazole is weak and special. Although the smell is not a critical property, it needs to be considered in some application scenarios that are sensitive to odor, such as food and fragrance fields. Weak odor can reduce the adverse effect on the sensory quality of the product, ensuring the safety and applicability of its application.
In addition, the density of 5-hydroxymethylthiazole is relatively moderate. Suitable density makes it easy to pack and measure during storage and transportation, maintains a stable physical state, and reduces the latent risk caused by abnormal density.
These physical properties are interrelated and jointly determine the application efficiency and scope of 5-hydroxymethylthiazole in many fields such as chemical industry, medicine, and materials.

5-Hydroxymethylthiazole, this is an organic compound. Its chemical properties are unique and worthy of investigation.
Looking at its structure, the thiazole ring is connected to the hydroxymethyl group. The thiazole ring is a five-membered heterocyclic ring containing sulfur and nitrogen, which has certain aromatic properties. And hydroxymethyl-CH ² OH, containing active hydroxyl groups, endows the compound with different chemical activities.
From the physical properties, due to the presence of hydroxymethyl groups, hydrogen bonds can be formed between molecules, resulting in boiling point, melting point or higher, and good solubility in water.
In terms of chemical activity, hydroxyl groups can undergo many reactions. It can be esterified with acids, and the carboxyl groups in the acids are dehydrated and condensed to form esters. In case of acetic acid, under specific conditions, or hydroxymethylthiazole acetate.
Hydroxyl groups are also easily oxidized. Under mild oxidation conditions, or as an aldehyde group, 5-formylthiazole is obtained; under strong oxidation, the aldehyde group can be oxidized to carboxyl groups to form 5-carboxylthiazole.
In addition, the nitrogen and sulfur atoms on the thiazole ring have lone pairs of electrons, which can be used as nucleophilic check points. React with electrophilic reagents such as halogenated hydrocarbons to introduce new substituents on the thiazole ring to expand the structure and properties of the compound.
Furthermore, the carbon-sulfur and carbon-nitrogen bonds in 5-hydroxymethylthiazole molecules are relatively stable, but under extreme conditions such as strong acid, strong base or high temperature, they may break, triggering complex chemical reactions and deriving various products. Its unique chemical properties make it potentially valuable in organic synthesis, drug development and other fields.

The preparation method of 5-hydroxymethylthiazole, although the ancient book "Tiangong Kaiwu" does not directly describe this substance, it can be deduced from the relevant chemical processes and preparation reasons.
First, it can be prepared by condensation reaction from raw materials containing sulfur, nitrogen and hydroxymethyl groups. First find suitable sulfur-containing compounds, such as mercaptan or thioether, which contain sulfur atoms and are the base of thiazole ring formation. Then find nitrogen-containing reagents, such as amines, to participate in cyclization. Hydroxymethyl sources can be obtained by reacting formaldehyde and alcohols under suitable conditions to obtain hydroxymethylation reagents, and then make them react with sulfur and nitrogen-containing raw materials. During the reaction, when temperature control, pressure control and reaction time are long, the condensation reaction is carried out in the direction of generating 5-hydroxymethylthiazole.
The second, or from thiazole derivatives, is prepared by hydroxymethylation. The thiazole matrix can be synthesized by the classic synthesis method, such as β-ketoate, thiourea and other raw materials. Then, the thiazole ring is hydroxymethylated with a suitable hydroxymethylation reagent, such as chloromethyl methyl ether, under the catalysis of a base. In the reaction, the strength of the base and the proportion of the reagent dosage need to be fine-tuned to prevent overreaction or side reactions.
Third, biosynthesis can still be used. Find microorganisms with specific enzyme systems, such as certain bacteria or fungi, whose enzymes can catalyze a series of biochemical reactions between sulfur and nitrogen substrates and formaldehyde donors to synthesize 5-hydroxymethylthiazole. This process requires controlling the culture conditions, such as medium composition, pH, temperature, ventilation, etc., so that the microorganisms can metabolize to the target product synthesis.
Although there is no specific preparation of 5-hydroxymethylthiazole in "Tiangong Kaizi", but by using the ancient understanding of chemical changes and the method of process regulation, today people can follow the above ideas, through repeated experiments and optimization, to obtain this substance.

I think what you are asking is about the market price range of 5-hydroxymethylthiazole. However, the price of this chemical product fluctuates immutably and is subject to many factors.
The difficulty of its preparation, the price of the raw materials used, and the amount of market demand all affect its price. If the preparation process is complicated, the raw materials are scarce and expensive, and the market is seeking it, the price will be high; on the contrary, if the process is simple, the raw materials are sufficient, and the demand is mediocre, the price will be low.
Today, if you want to know the price, when observing the chemical market, consult the merchants and experts in the industry. However, according to past examples, the price may vary depending on quality, purity, and batch. High purity, large-scale transactions, or different prices. In general, the price can range from a few dollars per gram to tens of dollars per gram, or even higher. It is difficult to generalize, and it must be investigated in detail according to the specific situation.