5-Ethenyl-4-methyl-thiazole

5-Vinyl-4-methyl-thiazole, this is an organic compound. It has a wide range of uses and plays an important role in the chemical and pharmaceutical fields.
In the chemical field, it is often used as a key intermediate in the synthesis of many complex organic compounds. Due to its unique chemical structure, it can participate in many organic reactions. Through the delicate organic synthesis strategy, through a series of reaction steps, it can be cleverly combined with other compounds to construct organic molecules with more complex structures and more unique functions. These organic molecules may emerge in the field of materials science as raw materials for the synthesis of polymer materials with special properties, such as materials with excellent electrical conductivity, optical properties or thermal stability, and contribute to the development of cutting-edge scientific and technological fields such as electronics and optics.
In the field of medicine, 5-vinyl-4-methyl-thiazole also plays a significant role. It may have potential biological activities and can interact with specific biological macromolecules in organisms, such as binding to proteins, nucleic acids, etc., which in turn affect specific physiological and biochemical processes in organisms. On this basis, researchers have carried out in-depth drug research and development work, hoping to develop new drugs with high efficiency and low toxicity by modifying and optimizing their structures, so as to overcome various diseases and contribute to human health and well-being.
5-vinyl-4-methyl-thiazole occupies an important position in the fields of chemical synthesis and pharmaceutical research and development due to its unique chemical properties, which is of great significance for promoting scientific and technological progress in related fields.

5-Vinyl-4-methyl-thiazole, this is an organic compound. Its physical properties are crucial and relevant to many practical applications.
First of all, its appearance, at room temperature, or in the form of a colorless to light yellow liquid, clear and with a specific luster, just like the clear wine, pure and attractive to explore.
As for its boiling point, about 190 - 200 ℃. Under this temperature condition, the substance gradually changes from liquid to gaseous state, just like the rising of the cloud, it needs to be controlled by the appropriate temperature to make its state change suitable for the needs. < Br >
In terms of melting point, it is usually around -10 ° C, just like the cold of winter. At this low temperature limit, matter condenses from liquid to solid, just like water turns into ice when it is cooled. Its morphological transformation is significantly affected by temperature.
The density is about 1.05 - 1.10 g/cm ³, which is slightly heavier than water. It is like a slightly heavier substance placed in water and will slowly sink. This property is of great significance in material separation and mixing operations.
Solubility is also an important physical property. It is slightly soluble in water, just like the oil drops in water, difficult to blend, but soluble in many organic solvents, such as ethanol, ether, etc., as if the wanderer meets the bosom friend and can blend with each other. This solubility determines its application in different solvent systems.
In addition, 5-vinyl-4-methyl-thiazole also has a certain volatility. In the air, its molecules are like smart spirits, slowly dissipating, and accompanied by a unique odor, either pungent or slightly aromatic. This odor characteristic is also one of the clues for its identification and application.
All these physical properties are intertwined, and they are all indispensable factors to consider in the research and production of chemical, pharmaceutical and other fields. They are related to experimental operation, product quality and performance, just like silk thread beads, which are the brocade of co-weaving applications.

5-Vinyl-4-methyl-thiazole, which is an organic compound with a thiazole ring in its structure, and is connected to methyl at the 4th position and vinyl at the 5th position.
In terms of its physical properties, it is mostly liquid or low-melting point solid at room temperature. Because the molecule contains heterocycles and unsaturated bonds, it has a certain polarity. It has good solubility in organic solvents such as ethanol and acetone, but relatively low solubility in water.
As for chemical properties, it has the typical reactivity of olefins due to its vinyl content. Addition reactions can occur. If it encounters bromine water, the double bond of the vinyl group can be added to bromine, causing the bromine water to fade; when it encounters hydrogen halides such as hydrogen chloride, it can also be added to generate corresponding halogenates. Under appropriate catalytic conditions, polymerization can also be carried out to form a polymer. In addition, the thiazole ring also gives it specific chemical activity. The presence of thiazole ring nitrogen atoms and sulfur atoms allows it to complex with metal ions as a ligand to form a stable complex. At the same time, the characteristics of the electron cloud density distribution on the ring allow it to participate in electrophilic substitution reactions, but compared with benzene rings, its reactivity and selectivity are different. 5-Vinyl-4-methyl-thiazole is widely used in the field of organic synthesis, and can be used as a key intermediate in the synthesis of complex organic compounds. It has important value in many disciplines such as medicinal chemistry and materials science.

The synthesis method of 5-vinyl-4-methyl-thiazole has been known for a long time. The synthesis of this compound often follows various paths.
First, it is obtained by ingenious chemical transformation from raw materials containing sulfur and nitrogen heterocycles. If a suitable thiazole derivative is selected, its side chain is enylated and vinyl is introduced; or a methylating agent is applied to the thiazole parent body to obtain 4-methyl-thiazole, and then vinylated. In the alkenylation step, or by nucleophilic substitution reaction, the active halogenated ethylene derivative and the thiazole derivative are selected under the action of a base to leave the halogen atom, and the alkenyl group is connected to the thiazole to form 5-vinyl-4-methyl-thiazole.
Second, start with the construction of the thiazole ring. Small molecules containing sulfur and nitrogen atoms are cyclized to form the thiazole ring synchronously and introduce vinyl and methyl. For example, under suitable conditions, β-ketothioamide and α-haloallyl compounds are cyclized and condensed in the molecule to obtain the target product. This reaction requires precise control of the reaction temperature, solvent and catalyst, so that each group can be precisely connected to form the desired structure.
Third, with the help of transition metal catalysis. Transition metals can activate chemical bonds in substrates and promote bonding reactions. Such as palladium-catalyzed cross-coupling reaction, with halide or borate containing vinyl and methyl, and thiazole derivatives under the action of palladium catalysts and ligands, carbon-carbon bonds are formed to obtain 5-vinyl-4-methyl-thiazole. This method has good selectivity and considerable yield, but the cost of the catalyst may be considered. < Br >
The synthesis of 5-vinyl-4-methyl-thiazole has its own advantages and disadvantages, and the choice should be weighed according to the availability of raw materials, the ease of control of reaction conditions and the requirements of product purity.

The price of 5-vinyl-4-methyl-thiazole in the market is difficult to determine. This causes its price to fluctuate due to various reasons. Looking at the past, the price of materials in the market often changed according to supply and demand, the complexity of the process, and the abundance of the source material.
If there are many people in need and the supply is thin, the price will rise; conversely, if the supply exceeds the demand, the price may drop. Furthermore, if the process of making this 5-vinyl-4-methyl-thiazole is complicated, requiring high technology and resources, the price will also be high; if the source material is wide and easy to obtain, the cost of production will decrease, and the price will also decrease.
However, I do not know the current market situation, nor do I have the exact price. To know the price, you can consult the chemical material supplier, or visit the chemical trade network, there may be a recent price for you to observe.