5 Ethenyl 4 Methyl 1 3 Thiazole
quinoline thiophene imidazole thiazole

5-ethenyl-4-methyl-1,3-thiazole

    Specifications

    HS Code

    141155

    Name 5-ethenyl-4-methyl-1,3-thiazole
    Chemical Formula C6H7NS
    Molar Mass 125.19 g/mol
    Solubility In Water poor (thiazoles are generally hydrophobic)
    Solubility In Organic Solvents good in common organic solvents like ethanol, acetone
    Odor characteristic thiazole - like odor (usually pungent)
    Reactivity can participate in electrophilic substitution reactions due to the presence of double bond and heterocyclic ring

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    Frequently Asked Questions

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    5-ethenyl-4-methyl-1, what are the chemical properties of 3-thiazole?
    5-Vinyl-4-methyl-1,3-thiazole, this is an organic compound. It has unique chemical properties and can be analyzed from the aspects of structure and reaction characteristics.
    Looking at its structure, the thiazole ring is the core, and there are vinyl and methyl groups connected to it. This structure gives it a specific electron cloud distribution and spatial configuration. The thiazole ring itself has certain aromatic properties and can stabilize the molecule. Vinyl contains carbon-carbon double bonds, which endow the compound with unsaturated properties and enable it to undergo addition reactions. Methyl groups are the power supply groups, which affect the molecular electron cloud density and reactivity.
    In terms of chemical reactivity, due to its unsaturated double bond, it is prone to addition reactions. If it is added with hydrogen halide, the double bond is opened, and the halogen atom and the hydrogen atom are respectively connected to the carbon at both ends of the double bond. And due to the presence of thiazole ring, it can participate in the nucleophilic substitution reaction, and the atoms on the ring can be used as nucleophilic check points to react with electrophilic reagents. Under appropriate conditions, polymerization may also occur, and vinyl groups are connected to each other to form polymers.
    In addition, the physical properties of the compound are also related to its structure. Due to the presence of polar heterocycles and unsaturated bonds, it should have a certain solubility in organic solvents, and its melting point, boiling point and other properties are also affected There are van der Waals forces between molecules, which affect their physical properties due to the difference of atomic electronegativity in the structure or a certain dipole-dipole interaction.
    5-ethenyl-4-methyl-1, what are the physical properties of 3-thiazole
    5-Vinyl-4-methyl-1,3-thiazole is one of the organic compounds. Its physical properties are worth exploring.
    Under normal conditions, it may be a colorless to light yellow liquid with a clear and special odor. This odor is unusual, unique and recognizable, and odor is often an important characteristic in the identification of organic chemicals.
    Its boiling point is also a key physical property. According to many experimental measurements and theoretical calculations, the value of this boiling point at a specific temperature range is related to its phase transition under different temperature conditions. In a high temperature environment, it is easy to turn into a gaseous state, and at low temperatures, it can maintain a liquid state. This property is widely used in chemical production and separation and purification processes.
    Furthermore, the melting point cannot be ignored. Although the exact melting point data varies slightly due to purity and measurement conditions, the approximate range can be found. The level of melting point reflects the strength of the intermolecular force and is also closely related to the stability of the compound.
    In terms of solubility, 5-vinyl-4-methyl-1,3-thiazole exhibits different degrees of solubility in organic solvents. In common organic solvents such as ethanol and ether, it can be moderately dissolved, but in water, the solubility is poor. The difference in solubility is due to the characteristics of the groups in their molecular structure, and the hydrophobicity of organic groups makes them insoluble in water.
    Density is also one of the elements of physical properties. Its density has a certain value after precise measurement, and this value is of great significance for the measurement of materials in chemical production and the design of reaction systems.
    In summary, the physical properties of 5-vinyl-4-methyl-1,3-thiazole, such as morphology, odor, boiling point, melting point, solubility and density, play a key role in the study of organic chemistry and the practice of chemical production, laying the foundation for in-depth understanding of this compound and related applications.
    5-ethenyl-4-methyl-1, what is the main use of 3-thiazole?
    5-Ethenyl-4-methyl-1,3-thiazole, Chinese name 5-vinyl-4-methyl-1,3-thiazole, is an organic compound with a wide range of uses.
    In the field of organic synthesis, this compound is often used as a key intermediate. Because its molecular structure contains thiazole rings and vinyl groups, thiazole rings have unique electronic properties and stability, while vinyl groups have high reactivity, and can be derived from various chemical reactions, such as addition, substitution, etc. Organic compounds with diverse structures. For example, in the construction of complex nitrogen-containing heterocyclic compounds, 5-vinyl-4-methyl-1,3-thiazole can connect the thiazole ring into the target molecular structure by substitution reaction with nucleophiles, laying the foundation for the creation of new organic functional molecules such as drugs and pesticides.
    In the field of materials science, 5-vinyl-4-methyl-1,3-thiazole is also used. Vinyl can participate in the polymerization reaction and copolymerize with other monomers to form polymeric materials. Due to the presence of thiazole rings, polymers are endowed with special properties, such as improving the thermal stability and chemical stability of materials. For example, in the preparation of high-performance engineering plastics, the introduction of this compound can optimize the mechanical properties and chemical resistance of the material, making it suitable for applications in aerospace, electronics and electrical appliances.
    In addition, in the field of medicinal chemistry, the biological activity of this compound has attracted much attention. Thiazole compounds often exhibit a variety of biological activities, such as antibacterial, anti-inflammatory, and anti-tumor. 5-vinyl-4-methyl-1,3-thiazole may be used as a lead compound to develop new drugs through structural modification and optimization. Researchers can design and synthesize a series of derivatives based on their structural characteristics, explore their interactions with biological targets, and search for drug candidates with higher activity and selectivity.
    5-ethenyl-4-methyl-1, what are the synthesis methods of 3-thiazole
    To prepare 5-vinyl-4-methyl-1,3-thiazole, there are many methods, and this is the number of Chen.
    First, it can be obtained from the condensation reaction of raw materials containing sulfur and nitrogen. Select the appropriate sulfur source and nitrogen source, and under specific reaction conditions, such as temperature control, pressure regulation, and appropriate catalysts, make them interact, and through complex molecular rearrangement, cyclization, etc., the thiazole structure is formed.
    Second, halogenate is used as the starting material. Halogenated hydrocarbons and reagents containing sulfur and nitrogen, under the action of bases or other promoters, first undergo nucleophilic substitution reaction, and then undergo intramolecular cyclization to achieve the synthesis of 5-vinyl-4-methyl-1,3-thiazole. This process requires fine regulation of the reaction process, because the activity of the halogen, the reaction solvent, and the strength of the base all have a great influence on the reaction.
    Third, the reaction can be catalyzed by transition metals. Transition metal catalysts such as palladium and copper can activate substrate molecules and promote the formation of carbon-carbon and carbon-heteroatomic bonds. Using compounds containing alkenyl, methyl, and thiazole structural fragments as raw materials, under the catalysis of transition metals, coupling reactions, etc. occur to assemble the required target molecules. However, such methods need to pay attention to the amount of catalyst and the selection of ligands to improve the selectivity and efficiency of the reaction.
    Synthesis of this compound requires weighing the availability of raw materials, cost, difficulty of reaction and purity of the product, and selecting the most suitable method to obtain it efficiently.
    5-ethenyl-4-methyl-1, what are the precautions for the use of 3-thiazole
    5-Vinyl-4-methyl-1,3-thiazole is an organic compound. During use, many key matters must be paid attention to.
    First safety protection. This compound may be toxic and irritating. When exposed, choose appropriate protective equipment. When operating, protective clothing is required, and the material should be able to effectively resist the erosion of the compound and protect the body from harm. Protective gloves should also be worn. The selected gloves must be well tolerated to 5-vinyl-4-methyl-1,3-thiazole to prevent contact with the skin of the hands. Facial protection is also indispensable. Wearing a protective mask can prevent the compound from splashing on the face, especially the eyes, and prevent damage to the eyes. At the same time, the operation should be carried out in a well-ventilated environment. The best choice is to operate in a fume hood, which can disperse volatile gases in time, reduce the concentration of the compound in the air, and reduce the risk of inhalation.
    The second time is to pay attention to its chemical properties. 5-vinyl-4-methyl-1,3-thiazole contains a vinyl and thiazole ring structure, which has high chemical activity. When storing, it should be kept away from strong oxidants, because it encounters with strong oxidants, which can easily cause violent oxidation reactions, and may even lead to combustion or explosion. It should not be stored together with strong acids and alkalis. Strong acids, strong bases or chemical reactions with the compound will cause its structure to change, which will not only affect the use effect, but also may generate dangerous products.
    Furthermore, the access and operation steps should also be rigorous. During the access process, be sure to use clean and suitable equipment. If a measuring tool is used, it needs to be calibrated in advance to ensure that the access dose is accurate. During operation, the action should be steady and slow to avoid the compound splashing due to excessive operation. If it is accidentally splashed, it should be dealt with immediately according to the established emergency procedures. If a small amount of splashing can be covered with a material with good adsorption first, and then properly collected and processed; when a large amount of splashing, in addition to rapid adsorption, the surrounding personnel should be evacuated in time to prevent poisoning and other accidents.
    In conclusion, when using 5-vinyl-4-methyl-1,3-thiazole, care must be taken from safety protection to chemical control to specific operation steps to ensure the safety and smoothness of the use process.