5-Chloro-2-mercaptobenzothiazole

5-Chloro-2-mercaptobenzothiazole, this substance has a wide range of uses. In the rubber industry, it is often used as an accelerator. It can speed up the vulcanization process of rubber, improve the physical properties and chemical stability of rubber products, such as enhancing the wear resistance and anti-aging of rubber, shortening the vulcanization time and improving production efficiency.
In the field of pesticides, it can be used as an intermediate. A variety of pesticide products can be prepared by chemical synthesis, which can inhibit or kill pests and diseases through its own chemical properties to protect the healthy growth of crops.
In the field of medicine and chemical industry, it also has important uses. It can be used as a raw material or intermediate to participate in drug synthesis. In the construction of some drug molecules with specific pharmacological activities, its structural units may play a key role in the development and production of drugs for the treatment of specific diseases.
In addition, in coatings, plastics and other industries, it may be used as an additive to endow products with properties such as anti-corrosion and anti-oxidation, optimize product performance, and broaden the scope of application. In short, 5-chloro-2-mercaptobenzothiazole is indispensable in many industrial fields and is of great significance to the development of related industries.

5-Chloro-2-mercaptobenzothiazole is one of the organic compounds. Its physical properties are particularly important, related to its use and characteristics.
Looking at its appearance, it often takes the form of a white-like to light yellow crystalline powder. This form is easy to identify, and in many reactions or application scenarios, the powder state is conducive to dispersion and mixing.
As for the melting point, it is about 180-186 ° C. The characteristics of the melting point are key indicators in the purification, identification and heating of substances. In this temperature range, the compound changes from a solid state to a liquid state, according to which the processing temperature conditions can be controlled.
In terms of solubility, it is slightly soluble in water. This characteristic shows that water is not its good solvent, and its dissolution limit needs to be considered in the reaction or application of water systems. However, it is soluble in organic solvents such as ethanol and acetone. Ethanol and acetone are common organic solvents. This solubility characteristic facilitates its application in organic synthesis, coatings, rubber additives, etc., because these organic solvents can be used to disperse them uniformly, participate in various reactions or exert their specific functions.
In addition, 5-chloro-2-mercaptobenzothiazole has a certain smell. Although the smell is not strong and pungent, it is also one end of its physical properties. In practical operation and application scenarios, it also needs appropriate attention.
In conclusion, the physical properties of 5-chloro-2-mercaptobenzothiazole, such as appearance, melting point, solubility, and odor, are of great significance for cognition, research, and practical application. This provides many key information for practitioners in related fields to utilize and develop this compound.

The stability of the chemical properties of 5-chloro-2-mercaptobenzothiazole depends on many aspects. In this compound, the chlorine atom interacts with the thiol group and benzothiazole ring, which affects its stability.
From the structural point of view, the benzothiazole ring has a conjugated system, which imparts certain stability. However, the sulfhydryl group has active hydrogen atoms and is easily oxidized, resulting in poor stability of the compound in an aerobic environment. If left in air for a long time, the thiol group may be gradually oxidized to disulfide bonds or other oxidation products, resulting in changes in its chemical properties.
And its stability is also affected by factors such as temperature and pH. Under high temperature, the thermal movement of molecules intensifies, the activity of chemical bonds is enhanced, or reactions such as decomposition are caused, and the stability is reduced. In acidic or alkaline environments, the chemical stability will also be affected due to protonation or deprotonation. For example, under strongly alkaline conditions, sulfhydryl groups are prone to react with bases, changing the structure and properties of compounds.
In summary, the chemical properties of 5-chloro-2-mercaptobenzothiazole are not absolutely stable. Under specific conditions, its structure and properties are prone to change.

5-Chloro-2-mercaptobenzothiazole, there are many ways to make it. The ancient method is mostly based on benzothiazole, obtained by chlorination and mercaptoylation.
Take benzothiazole first, use an appropriate chlorinating agent, such as chlorine gas or a chlorine-containing reagent, and under specific reaction conditions, such as in a suitable solvent, such as an organic solvent, control the temperature and reaction time, so that a specific position on the ring of benzothiazole, that is, the 5-position, introduces a chlorine atom to obtain 5-chlorobenzothiazole. Then 5-chlorobenzothiazole is reacted with sulfhydryl reagents such as sodium hydrosulfide. This reaction also needs to be carried out under suitable solvents and reaction conditions, such as in an alkaline environment, to promote the substitution of chlorine atoms on 5-chlorobenzothiazole by sulfhydryl groups. After this step, 5-chloro-2-mercaptobenzothiazole is obtained. < Br >
There is another method, using o-chloroaniline as the starting material, reacting with carbon disulfide and sulfur under basic conditions to form 2-mercaptobenzothiazole intermediates. After chlorination, chlorine atoms are introduced at the 5-position, and 5-chloro-2-mercaptobenzothiazole can also be obtained. During the reaction, various reaction conditions, such as temperature, reagent ratio, reaction time, etc., need to be carefully adjusted to increase the yield and purity of the product.

The price of 5-chloro-2-mercaptobenzothiazole in the market varies with time, place, quality and supply and demand conditions, and it is difficult to determine the exact number. In the past, "Tiangong Kaiwu" tried to say that the price of various things changed with the situation, and the same is true.
If the recent market is extrapolated, the industrial grade and the purity is about the ordinary level, the price per kilogram may be around 100 yuan. However, if the purity is improved, such as reaching the high purity pharmaceutical grade, the price can rise several times, or to hundreds of yuan per kilogram.
The supply and demand of the city is also a major factor. If demand exceeds supply, if the pharmaceutical industry's demand for it increases sharply at a certain time, its price will rise; on the contrary, if supply exceeds demand, the price may drop. And the origin is far and near, and the cost of transportation also involves its price. For those who are transported from afar, the price may be higher than that produced nearby due to additional freight.
And the price of chemical raw materials often fluctuates due to raw material costs and changes in policies and regulations. If the price of upstream raw materials increases, or the production cost increases due to stricter environmental protection policies, the price of 5-chloro-2-mercaptobenzothiazole will also rise. Therefore, the price is about tens of yuan to hundreds of yuan per kilogram, which is difficult to determine. The market conditions are ever-changing, and real-time prices need to be consulted by chemical material suppliers or market brokers.