5-(Benzoylamino)-N-(p-chlorophenyl)-3-methyl-4-isothiazolecarboxamide

5- (benzoylamino) -N- (p-chlorophenyl) -3-methyl-4-isothiazolecarbonamide, this is an organic compound. To clarify its chemical structure, its name needs to be analyzed to know the connection of each group.
"5- (benzoylamino) ", said to be in the 5th position of the isothiazole ring, connected with benzoylamino. Benzoyl group, obtained by dehydroxylation of benzoic acid, has the structure of benzene cyclocarbonyl (-CO -), and the amino group (-NH 2) is connected to the carbon of the carbonyl group to form benzoylamino (-CONH -).
"N - (p-chlorophenyl) " shows that the nitrogen atom is connected to the p-chlorophenyl group. The phenyl group is the group left by the removal of a hydrogen atom from the benzene ring, and the p-chlorophenyl group, that is, the p-position of the benzene ring, has a chlorine atom substituted.
The 3rd position of the "3-methyl" epithiazole ring is connected by a methyl group (-CH 🥰).
"4-isothiazole formamide" It is said that the core of this compound is an isothiazole ring, and the 4-position formamide group is attached. The isothiazole ring has nitrogen and sulfur heteroatoms, and the formamide group is formyl (-CHO) and is connected to the amino group, namely -CONH.
In summary, this compound uses an isothiazole ring as the core, with 3-position methylation, 4-position formamide, and 5-position benzoamide, and N- (p-chlorophenyl) attached to related atoms. Its structure is complex and delicate, and each group affects each other, giving this compound unique physicochemical and biological activities.

5- (benzoylamino) -N- (p-chlorophenyl) -3 -methyl-4 -isothiazolecarbonamide, this is an organic compound. Its physical properties are very critical and are of great significance in the fields of chemical industry, medicine and other fields.
Looking at its appearance, it is mostly white to light yellow crystalline powder under normal circumstances, fine and uniform in quality. This appearance characteristic is easy to distinguish and handle. During production operations, it is easy to observe its properties changes to ensure stable product quality.
Talking about the melting point, it is between 190-195 ° C. As a material characteristic, the melting point is crucial for the determination of purity. If the melting point deviates from this range, it may suggest that the purity of the substance is poor and contains more impurities.
Its solubility also needs to be paid attention to. It is slightly soluble in water, but it can be soluble in organic solvents such as dichloromethane, N, N-dimethylformamide. This solubility characteristic has a great impact on the chemical synthesis, separation and purification steps. For example, in the construction of the reaction system, a suitable solvent needs to be selected to ensure the smooth progress of the reaction; in the process of product purification, high-purity products can be obtained by extraction and other means according to the difference in solubility.
In addition, the density of the compound is about 1.45 - 1.55 g/cm ³. Density data is of great significance in material measurement, storage and transportation planning. It can help to accurately control the dosage, rationally design storage containers, and ensure transportation safety. The physical properties of 5- (benzoylamino) -N- (p-chlorophenyl) -3 -methyl-4 -isothiazolecarbonamide have a profound impact on its application in various fields, and its effectiveness can only be fully exerted if it is carefully mastered.

5- (benzoylamino) -N- (p-chlorophenyl) -3-methyl-4-isothiazolecarbonamide is a complex organic compound. Its main uses are quite extensive, in the field of medicine, often used as a key intermediate for drug research and development. Due to its unique chemical structure, it can be combined with other compounds through specific chemical reactions to construct new drug molecules with specific pharmacological activities.
It also plays an important role in scientific research. Scientists can gain insight into the chemical properties and reaction laws of isothiazoles through in-depth study of their structures and properties, providing theoretical basis and practical experience for the development of organic synthetic chemistry. At the same time, in the field of pesticide creation, it may have potential application value. After reasonable modification and modification, new pesticides with high efficiency, low toxicity and environmental friendliness may be developed to help the control of agricultural pests and diseases.
In summary, 5- (benzoamido) -N- (p-chlorophenyl) -3-methyl-4-isothiazole formamide has shown important uses in many fields such as medicine, scientific research and pesticides, providing indispensable support for the progress and development of related industries.

The synthesis of 5 - (benzoylamino) - N - (p-chlorophenyl) - 3 - methyl - 4 - isothiazole formamide is an important topic in the field of organic synthesis. Although the synthesis of this specific compound is not directly covered in "Tiangong Kaiwu", the chemical principles and traditional technical thinking contained in it are also enlightening today.
To synthesize this compound, there are many paths. First, isothiazole is used as the starting material and benzoylamino is introduced through acylation reaction. In this process, suitable acylating reagents, such as benzoyl chloride, need to be selected. Under the catalysis of alkali, nucleophilic substitution occurs with specific positions of isothiazole to form isothiazole intermediates containing benzoyl groups.
Then, the intermediate is reacted with p-chloroaniline to construct a connection of N - (p-chlorophenyl). This reaction may require the assistance of catalysts, such as copper salts, etc., through nucleophilic substitution or coupling reaction mechanisms, this part of the target structure can be connected. Reaction conditions such as temperature and solvent need to be carefully regulated to obtain higher yields. < Br >
Furthermore, the introduction of methyl groups during the synthesis process may be considered in the design of starting materials, and methyl groups are introduced at the 3-position of the isothiazole ring through a specific substitution reaction. This step also requires consideration of reaction conditions and reagent selection to ensure the precise introduction of methyl groups without affecting other functional groups.
Or from other compounds containing related functional groups, the target molecular structure can be gradually constructed through multi-step reactions. For example, thiazole derivatives containing specific substituents are synthesized first, and then the steps of functional group conversion and linking are used to achieve the synthesis of 5- (benzoylamino) -N- (p-chlorophenyl) -3-methyl-4-isothiazole formamide. Each step of the reaction needs to be planned in detail, and attention should be paid to the reaction sequence and condition control to obtain a pure product.

5 - (benzoylamino) - N - (p-chlorophenyl) - 3 - methyl - 4 - isothiazolecarbonamide, when using this product, all matters need to be paid attention to.
First, safety comes first. This substance may be toxic and irritating, so when handling, strictly follow safety procedures. Be sure to wear protective clothing, such as laboratory clothes, gloves, and protective goggles to prevent it from contacting the skin and eyes. If you accidentally touch it, rinse it with plenty of water immediately, and according to the specific situation, or seek medical treatment.
Second, accurately weigh and prepare. When using this product, accuracy is essential. In the weighing process, accurate instruments are required to ensure that the dosage is correct. The preparation of the solution should also strictly follow the established steps and proportions to ensure accurate concentration. A slight deviation may cause the experimental results to be wrong, or affect the quality of the product.
Third, environmental conditions. Temperature, humidity, light, etc., can all affect the properties and reactions of this substance. Generally speaking, it should be stored in a dry, cool and dark place. If it is used in a specific reaction, it is necessary to accurately control temperature and humidity to meet the needs of the reaction.
Fourth, compatibility is contraindicated. It is necessary to make it clear that it is contraindicated for compatibility with other substances. Or react violently with certain compounds, or even explode and produce harmful gases. Therefore, before use, be sure to check the relevant information carefully to avoid contact with contraindicated substances.
Fifth, proper disposal. After use, the residue should not be discarded at will. It should be properly disposed of in accordance with relevant regulations to prevent environmental pollution or potential safety hazards. Used containers should also be washed and stored properly. In this way, the safe and effective use process can be ensured.