5 Benzoylamino N 4 Chlorophenyl 3 Methyl 1 2 Thiazole 4 Carboxamide
quinoline thiophene imidazole thiazole

5-(benzoylamino)-N-(4-chlorophenyl)-3-methyl-1,2-thiazole-4-carboxamide

    Specifications

    HS Code

    188184

    Chemical Formula C18H14ClN3O2S
    Molecular Weight 371.84 g/mol
    Appearance Solid (usually)
    Physical State At Room Temp Solid
    Solubility In Water Low solubility (likely)
    Solubility In Organic Solvents May dissolve in some organic solvents like DMSO
    Melting Point Specific value would require literature search
    Boiling Point Specific value would require literature search
    Pka Specific value would require literature search

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    Frequently Asked Questions

    As a leading 5-(benzoylamino)-N-(4-chlorophenyl)-3-methyl-1,2-thiazole-4-carboxamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    5- (benzoylamino) -N- (4-chlorophenyl) -3-methyl-1, what is the chemical structure of 2-thiazole-4-carboxamide
    This is the chemical structure of 5- (benzoamido) -N- (4-chlorophenyl) -3-methyl-1,2-thiazole-4-formamide. The structure of this compound is composed of a thiazole ring as the core, with benzoamido at the 5th position and methyl substitution at the 3rd position. The 4th position of the thiazole ring is connected to the formamide group, and the nitrogen atom of the formamido group is connected to the 4-chlorophenyl group.
    Specifically, the thiazole ring is a five-membered heterocyclic structure composed of a sulfur atom and a nitrogen atom at the 1,2 position. The benzoyl group at position 5, that is, the benzoyl group (connected by phenyl and carbonyl) is bound to the amino group and then attached to the thiazole ring at position 5. The methyl group at position 3 is a simple -CH < unk > group. The formamide group at position 4 is the carbonyl group connected to the amino group and then connected to the thiazole ring, and the nitrogen atom of the formamide group is connected to 4-chlorophenyl, and 4-chlorophenyl is the group obtained by the substitution of the fourth position of the benzene ring by the chlorine atom. Thus, the chemical structure of 5- (benzoylamino) -N- (4-chlorophenyl) -3-methyl-1,2-thiazole-4-formamide is formed.
    5- (benzoylamino) -N- (4-chlorophenyl) -3-methyl-1, what is the main use of 2-thiazole-4-carboxamide
    5- (benzoylamino) -N- (4-chlorophenyl) -3-methyl-1,2-thiazole-4-formamide, this is an organic compound. Looking at its structure and properties, it is often used as a lead compound in the field of medicinal chemistry to assist the development of new drugs.
    Because of its unique structure, it has the potential to interact with specific targets in organisms, or it can exhibit a variety of biological activities. In the search for antibacterial drugs, it may be combined with key bacterial enzymes or proteins to interfere with the normal physiological metabolism of bacteria and achieve antibacterial effect. In the development of anti-tumor drugs, it may also exert potential anti-cancer activity by affecting the signaling pathways of tumor cells and inhibiting the proliferation of tumor cells.
    In addition, in the field of pesticide chemistry, it may also have its uses. It can be designed as a new type of insecticide or fungicide, using its effect on specific targets of insects or pathogens to control pests and diseases, and compared with traditional pesticides, it may have higher selectivity and lower environmental toxicity, providing a new way for sustainable agricultural development. In conclusion, 5- (benzoylamino) -N- (4-chlorophenyl) -3-methyl-1,2-thiazole-4-formamide has broad application prospects in the fields of medicine and pesticide research and development due to its own structural characteristics, and can be used as an important research object to promote innovation and development in related fields.
    What are the synthesis methods of 5- (benzoylamino) -N- (4-chlorophenyl) -3-methyl-1, 2-thiazole-4-carboxamide
    To prepare 5- (benzoylamino) -N- (4-chlorophenyl) -3-methyl-1,2-thiazole-4-formamide, there are many methods, the following is one.
    First take an appropriate amount of 3-methyl-1,2-thiazole-4-formic acid, place it in a reactor, add an appropriate amount of dichlorosulfoxide, add a catalyst amount of N, N-dimethylformamide, heat up to 50-60 ℃, stir the reaction for 2-3 hours, until the reaction is complete, remove excess dichlorosulfoxide by reduced pressure distillation to obtain 3-methyl-1,2-thiazole-4-formyl chloride. < Br >
    Take another 4-chloroaniline, dissolve an appropriate amount of anhydrous dichloromethane, cool in an ice bath, slowly add the obtained 3-methyl-1,2-thiazole-4-formyl chloride solution of anhydrous dichloromethane, while adding an appropriate amount of triethylamine as an acid binding agent, maintain the temperature 0-5 ℃, drop, move to room temperature, stir the reaction 4-6 hours. After the reaction is completed, the reaction solution is washed with dilute hydrochloric acid solution, followed by saturated sodium bicarbonate solution, then washed with water, dried with anhydrous sodium sulfate, filtered, and the solvent is removed by reduced pressure distillation to obtain N- (4-chlorophenyl) -3 -methyl-1,2-thiazole-4-formamide.
    This product is mixed with benzoyl chloride, and an appropriate amount of pyridine is used as the solvent, and the reaction is stirred at room temperature for 8-10 hours. After the reaction is completed, it is poured into ice water, the solid precipitates, filtered by suction, and the filter cake is recrystallized with ethanol to obtain 5- (benzoylamino) -N- (4-chlorophenyl) -3-methyl-1,2-thiazole-4-formamide.
    This is only one method. In actual operation, the appropriate method can be selected according to different raw materials, equipment and reaction conditions, and the reaction conditions of each step need to be carefully controlled to improve the purity and yield of the product.
    5- (benzoylamino) -N- (4-chlorophenyl) -3-methyl-1, what are the physical and chemical properties of 2-thiazole-4-carboxamide
    5- (benzoylamino) -N- (4-chlorophenyl) -3-methyl-1,2-thiazole-4-formamide, this substance has different properties and multiple physicochemical characteristics.
    Looking at its properties, under normal circumstances, it may be a crystalline body with a white color, like frost and snow, pure in quality and density, with a certain luster, just like the moisture of good jade. Its melting point is quite critical, about a certain temperature range. At this point, the crystalline solid begins to melt into a liquid. This temperature is its inherent property, just like a person's birthday, and is an important basis for identifying this object. < Br >
    In terms of solubility, it varies in many common solvents. In polar solvents, such as water, it is slightly soluble. Although it cannot be greatly soluble, it is like a drizzle moisturizing sand and slightly melted; while in organic solvents, such as ethanol and acetone, the solubility is slightly better. It can be analogous to salt entering a warm soup and gradually melting into it, which can form a uniform dispersion system.
    Stability is also an important physical property. When it is at room temperature and pressure without special chemical environment interference, its structure is stable, like a strong city, with molecules holding each other back and difficult to change. In the presence of strong acids and alkalis, or high temperatures and hot topics, the structure will be like a house under wind and rain, gradually disintegrating, and chemical reactions will occur, resulting in the loss of its original characteristics.
    Furthermore, its spectral characteristics cannot be ignored. In the infrared spectrum, the vibration absorption peaks of each chemical bond are clearly distinguishable, just like unique fingerprints, according to which its structure can be accurately identified; in the ultraviolet spectrum, specific absorption peaks reveal the characteristics of its conjugate system, providing clues for the study of its electron transition and molecular structure. These spectral characteristics, such as bright lights, help researchers to understand the mysteries of its microstructure.
    5- (benzoylamino) -N- (4-chlorophenyl) -3-methyl-1, what is the market prospect of 2-thiazole-4-carboxamide
    5- (benzoylamino) -N- (4-chlorophenyl) -3-methyl-1,2-thiazole-4-formamide is a promising compound. In today's market prospects, there seem to be many things to be explored.
    In the past, chemical substances have entered the market through a complicated process. This compound is no exception. At the beginning, in the synthesis stage of the laboratory, researchers spent a lot of effort to obtain a purer product. To make it stand out in the market, it still takes several hurdles.
    In the field of medicine, this compound may have unique pharmacological activities. If it can show significant therapeutic efficacy and have minimal side effects, it must attract the attention of pharmaceutical companies. However, the pharmaceutical market is strictly regulated, and new drugs need to undergo multiple clinical trials to prove their safety and effectiveness. This process is long and expensive. If the trial goes well, it may occupy a seat in the pharmaceutical market in a few years, bringing good news to patients.
    In agriculture, if it has the ability to inhibit and kill pests and pathogens, it may be developed into a new type of pesticide. However, the agricultural market is highly competitive, and many existing pesticide products have been deeply rooted. If this compound wants to gain a share, it needs to highlight its unique advantages, such as high efficiency, low toxicity, and environmental protection, in order to win the favor of farmers.
    Furthermore, the chemical industry may also be its market location. If it can be used as an intermediate to synthesize other high-value-added chemicals, it can also find opportunities for development in the chemical industry chain. However, the chemical market is greatly affected by raw material prices and technological innovation, and it needs to keep up with industry trends in order to cope with it easily.
    In summary, 5- (benzoylamino) -N- (4-chlorophenyl) -3-methyl-1,2-thiazole-4-formamide has potential, but in order to achieve market success, it still needs to overcome many difficulties. It is expected to develop a broad market prospect due to the situation.