5 Aminothiazole 4 Carboxamide
quinoline thiophene imidazole thiazole

5-aminothiazole-4-carboxamide

    Specifications

    HS Code

    568547

    Chemical Formula C4H5N3O
    Molar Mass 111.103 g/mol
    Appearance Solid
    Melting Point 196 - 200 °C
    Solubility In Water Moderately soluble
    Pka Approx. 4 - 5 (estimate for the acidic group)
    Boiling Point Decomposes before boiling
    Stability Stable under normal conditions

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    General Information
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    Frequently Asked Questions

    As a leading 5-aminothiazole-4-carboxamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 5-aminothiazole-4-carboxamide?
    5-Aminothiazole-4-formamide is an organic compound. Its main uses are quite extensive, and it has important applications in many fields.
    The first is in the field of medicinal chemistry. In this field, 5-aminothiazole-4-formamide is often a key intermediate in the synthesis of drugs. Because of its unique chemical structure, it can participate in the construction of a variety of drug molecules. Many drugs with specific biological activities are derived from its use as a starting material or an important structural fragment through a series of chemical reactions. For example, some anti-tumor drugs have used this compound to inhibit the growth and proliferation of tumor cells. Its structural properties enable it to interact with specific targets in tumor cells, or block key signaling pathways, thus exerting therapeutic effects.
    Furthermore, in the field of pesticide chemistry, this compound also has a place. It can be used as an important component in the synthesis of new pesticides. After appropriate chemical modification and modification, pesticides with high-efficiency control ability on crop diseases and insect pests can be prepared. Its mechanism of action may interfere with the physiological metabolism of pests, or inhibit the growth and reproduction of pathogens, thereby protecting crops and improving yield and quality.
    In addition, in the field of materials science, 5-aminothiazole-4-formamide has also shown potential uses. It can participate in the synthesis of some functional materials, giving materials special properties. For example, in the preparation of some materials with special optical or electrical properties, this compound can be used as a functional monomer to affect the microstructure and macroscopic properties of materials, providing new ideas and approaches for the development of materials science.
    In summary, 5-aminothiazole-4-formamide has important uses in the fields of medicine, pesticides and materials science due to its unique chemical structure and reactivity, which cannot be ignored, promoting the continuous progress and development of related fields.
    What are 5-aminothiazole-4-carboxamide synthesis methods?
    5-Aminothiazole-4-formamide is an important compound in the field of organic synthesis. The synthesis method has been explored in the past.
    One method can be started from sulfur-containing and nitrogen-containing raw materials. If the appropriate thioamide and halogenated carbonyl compound are used as the starting point, and the two are cyclized under suitable reaction conditions to form a thiazole ring. In this process, the halogen atom of the halogenated carbonyl compound undergoes nucleophilic substitution with the sulfur atom of the thioamide, and then the nitrogen atom participates in the cyclization, resulting in the thiazole ring structure. Subsequent to the appropriate amination reaction, the amino group is introduced at the 5th position of the thiazole ring, and the carboxylamide group is modified at the 4th position to obtain 5-aminothiazole-4-formamide.
    Another method is to use thiazole compounds as substrates and first functionalize their specific positions. For example, groups that can be converted into carboxyamide groups, such as acyl chloride groups, ester groups, etc. are introduced before the 4th position of the thiazole ring, and converted into carboxyamide groups through corresponding reactions. Then the 5-position is aminized, and a suitable aminization reagent can be selected. Under the action of a suitable reaction medium and catalyst, the introduction of 5-amino groups is achieved, and the final target product is obtained. < Br >
    Another method is to construct the target structure by multi-step reaction of nitrogen-containing heterocyclic ring and sulfur-containing reagent. First, the nitrogen-containing heterocyclic compound reacts with sulfur-containing reagent to form a preliminary intermediate. This intermediate is then converted in multiple steps to gradually build a thiazole ring and introduce the required amino and carboxyamide groups. Pay attention to the control of reaction conditions in each step, such as temperature, pH, reaction time, etc., to ensure that the reaction proceeds in the desired direction and improve the yield and purity of the product.
    What are the physical and chemical properties of 5-aminothiazole-4-carboxamide?
    5-Aminothiazole-4-formamide, this material property is also related to the category of chemistry. Its shape, at room temperature, or a solid powder, is white in color and fine in texture. Its taste, or a specific smell, should not be smelled lightly to prevent damage to the body.
    Looking at its solubility, it has a certain solubility in water, and can be mixed with water, but it is not infinitely soluble, and it also has its limits. In organic solvents, such as ethanol, acetone, etc., its solubility varies, either easily soluble or difficult to dissolve, depending on the nature of the solvent.
    In terms of its stability, it is relatively stable under normal temperature and humidity conditions. However, when it encounters strong acids, strong bases, or hot topics, it is easy to change, and the molecular structure may be damaged, triggering chemical reactions and generating new substances.
    5-Aminothiazole-4-formamide, because of its unique physical and chemical properties, is important in medicine, chemical industry and other fields. In medicine, it can be used as a key raw material for synthetic drugs, assisting in the creation of new drugs, and seeking well-being for the treatment of diseases. In the chemical industry, it can also contribute to the preparation of fine chemicals and exert its unique effectiveness.
    5-aminothiazole-4-carboxamide in what areas?
    5-Aminothiazole-4-formamide has applications in the fields of medicine, agriculture, and materials science.
    In the field of medicine, it is the key to drug development. It can be used as an intermediate for the synthesis of many biologically active compounds. Because of its unique structure, it can interact with specific targets in organisms. Or it can be used for the development of anti-cancer drugs, by interfering with the signaling pathways related to the proliferation of cancer cells, to inhibit the growth of cancer cells. Or it can be used in the synthesis of antiviral drugs, by binding to key viral proteins to prevent virus replication.
    In agriculture, 5-aminothiazole-4-formamide may be used as a starting material for the creation of pesticides. Compounds with high inhibitory activity against pests can be derived, and compared with traditional pesticides, such derivatives may have higher selectivity, less damage to beneficial insects, and are environmentally friendly. It may also be used in the synthesis of plant growth regulators to regulate plant growth and development, improve crop yield and quality.
    In the field of materials science, this compound can be used to synthesize special functional materials. Because it contains specific functional groups, it can be chemically modified into polymer materials to give special properties such as fluorescence and electrical conductivity. In the preparation of optoelectronic materials, it may improve the electronic transmission properties of materials and improve device efficiency.
    In summary, 5-aminothiazole-4-formamide has potential and important applications in many fields due to its structural characteristics, providing new opportunities and directions for the development of various fields.
    What is the market outlook for 5-aminothiazole-4-carboxamide?
    5-Aminothiazole-4-formamide, the market prospect of this product today is still uncertain. Looking at the past, there is no obvious news, but in today's world, science and technology are changing day by day, and the field of pharmaceutical and chemical industry may have a chance to emerge.
    As far as medicine is concerned, many new drug research often relies on these characteristic compounds as the basis. If it can advance in the study of the mechanism of anti-disease, it may be the key to the creation of new special agents. Such as cancer and infection, if the effect of this substance and the focus can be explored, or a new way to develop new drugs can be opened, the market demand can be revived. < Br >
    In the chemical industry, it may be a key raw material for the synthesis of specific materials. In today's world, there is a growing need for materials with special properties. If we can use this as a basis to synthesize materials with unique physical and chemical properties, such as high stability and specific adsorption, it can have a place in electronics and environmental protection, and the market capacity may be considerable.
    However, it also faces challenges. If the synthesis method is not efficient, environmentally friendly, and the cost remains high, it will be difficult for the market to accept it. And the research and development of new drugs must go through layers of rigorous verification, the cycle is long, and the risk is quite high. If you want to take the lead in the market, you must be dedicated to all aspects of research and development and production in order to hopefully open up a world where the potential of this material can be developed and gain a place in the market.