4 Propan 2 Yl 1 3 Thiazole 2 Carboxylic Acid
quinoline thiophene imidazole thiazole

4-(propan-2-yl)-1,3-thiazole-2-carboxylic acid

    Specifications

    HS Code

    833943

    Name 4-(propan-2-yl)-1,3-thiazole-2-carboxylic acid
    Molecular Formula C7H9NO2S
    Molecular Weight 171.22
    Appearance Solid (predicted)
    Boiling Point 315.6°C at 760 mmHg (predicted)
    Melting Point 137 - 141°C
    Density 1.276 g/cm³ (predicted)
    Flash Point 144.7°C (predicted)
    Solubility Soluble in organic solvents like DMSO, methanol (predicted)
    Pka 3.54 (predicted)

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    General Information
    Where to Buy 4-(propan-2-yl)-1,3-thiazole-2-carboxylic acid in China?
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    Frequently Asked Questions

    As a leading 4-(propan-2-yl)-1,3-thiazole-2-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 4- (propan-2-yl) -1,3-thiazole-2-carboxylic acid?
    This is the chemical structure of 4- (isopropyl) -1,3 -thiazole-2 -carboxylic acid. In this compound, the thiazole ring is the core structure, consisting of a sulfur atom and a nitrogen atom coexisting in the five-membered ring. At the 2nd position of the thiazole ring, there is a carboxyl group connected by a carbon-oxygen double bond and a hydroxy group, which has acidic properties. At the 4th position of the thiazole ring, there is an isopropyl group connected, which is formed by a central carbon atom connected to two methyl groups.
    Looking at this structure, the thiazole ring endows the compound with unique stability and reactivity. Carboxyl groups can participate in many chemical reactions, such as ester reactions, salt reactions, etc., and are a key reaction check point in organic synthesis. The existence of isopropyl groups affects the spatial structure and physicochemical properties of molecules, such as increasing the lipid solubility of molecules and affecting their solubility in different solvents. The characteristics of this structure determine that it may have important uses in organic synthesis, pharmaceutical chemistry and other fields, and can be used as a key intermediate for the synthesis of specific drugs or functional materials.
    What are the physical properties of 4- (propan-2-yl) -1,3-thiazole-2-carboxylic acid?
    4- (isopropyl) -1,3-thiazole-2-carboxylic acid, this material has many physical properties. In appearance, it is mostly white to pale yellow crystalline powder at room temperature, delicate and uniform in texture, like fine snow falling at the beginning of winter, pure and simple.
    When it comes to solubility, in organic solvents, such as ethanol, acetone, etc., it can show good solubility, just like fish entering water and quietly fusing; however, in water, its solubility is relatively limited, only slightly soluble, like water droplets on lotus leaves, it is difficult to fully integrate. The melting point of
    is also one of the important physical properties. After measurement, its melting point is in a specific temperature range. This temperature gives it an opportunity to transform from solid to liquid, just like ice meets warm sun and changes the state of matter. Near the melting point temperature, the intermolecular forces undergo subtle changes, the lattice structure gradually disintegrates, and the material state changes accordingly.
    In addition, its stability cannot be ignored. Under conventional conditions, it can maintain a relatively stable state, just like a calm old man, calm and calm. In case of extreme chemical environments such as strong acids and alkalis, it is like throwing boulders into a calm lake. Its structure is easily damaged, triggering chemical reactions and generating other substances. < Br >
    In terms of smell, this object is almost odorless, or only has an extremely weak special smell, which can only be detected by smelling it carefully, just like a faint fragrance hidden in the hustle and bustle, fleeting.
    Density is also one of its physical characteristics, and its density value can be known by accurate measurement. This value reflects the degree of close arrangement of particles inside the material, just like an indicator of the density of a building structure, which determines its many behaviors in a specific environment.
    What are the applications of 4- (propan-2-yl) -1,3-thiazole-2-carboxylic acid?
    4- (isopropyl) -1,3-thiazole-2-carboxylic acids are useful in the fields of medicine, agriculture and materials.
    In the field of medicine, it can be used as a key intermediate for drug synthesis. Because of its unique biological activity in the structure of thiazole ring, it can interact with specific targets in organisms. In terms of antibacterial drugs, by modifying the structure of this compound, new antibacterial agents may be developed to inhibit or kill specific bacteria. In the development of anticancer drugs, by introducing isopropyl and thiazole-2-carboxylic acid structures, drugs that target cancer cells can be designed to interfere with the metabolism or proliferation of cancer cells and achieve the purpose of treating tumors.
    In the context of agriculture, it can be used as an important raw material for pesticide creation. In view of the fact that thiazole compounds often have good bactericidal and insecticidal activities, the 4- (isopropyl) -1,3-thiazole-2-carboxylic acid can be modified to develop highly efficient, low-toxic and environmentally friendly pesticides. For example, for common diseases of crops, the development of microbicides with internal absorption, after being absorbed by plants, play a bactericidal role in the body, protect crops from pathogens, and ensure agricultural harvests.
    As for the field of materials, it may participate in the synthesis of functional materials. Because of its special structure, or endow the material with unique physical and chemical properties. For example, in the preparation of polymer materials, the introduction of this compound as a comonomer may change the thermal stability, mechanical properties or optical properties of the material. After rational design and synthesis, high-performance materials suitable for specific fields, such as aerospace, electronic devices, etc. Special materials required in the field.
    What are the synthesis methods of 4- (propan-2-yl) -1,3-thiazole-2-carboxylic acid?
    The synthesis of 4- (isopropyl) -1,3-thiazole-2-carboxylic acids is an interesting topic in the field of organic synthesis. There are many common paths to make this compound.
    First, it can be initiated by sulfur-containing compounds and carbonyl compounds. First, take suitable sulfur-containing raw materials, such as thiourea or thioamide, and react with carbonyl compounds with corresponding structures under specific conditions. This reaction requires fine regulation of temperature, pH and solvent environment. Too high or too low temperature may affect the reaction process and product purity. For example, in a suitable basic solvent, when the temperature is raised to a certain extent, the cyclization reaction may occur between the two to initially construct the structure of the thiazole ring. Subsequent to this, the structure of the target molecule can be improved by introducing isopropyl groups. When introducing isopropyl, a suitable halogenated isopropyl reagent can be selected, and with the help of a metal catalyst, a nucleophilic substitution reaction can be achieved.
    Second, thiazole compounds can also be used as starting materials. Existing thiazole derivatives are modified to selectively introduce carboxyl and isopropyl groups at specific positions. In this process, the introduction of carboxyl groups may be achieved by carboxylation. If a suitable carboxylating reagent is used, a carboxyl group is introduced at the 2-position of the thiazole ring under specific reaction conditions. As for the addition of isopropyl groups, suitable alkylating reagents can be used according to the conventional methods of organic synthesis and completed in an appropriate reaction system.
    The key to synthesis lies in the precise control of the reaction conditions at each step, the appropriate selection of solvents, the rational use of catalysts, and the effective separation and purification of intermediates. Only in this way can 4- (isopropyl) -1,3-thiazole-2-carboxylic acids be obtained in high yield and purity.
    What is the market outlook for 4- (propan-2-yl) -1,3-thiazole-2-carboxylic acid?
    4- (isopropyl) -1,3-thiazole-2-carboxylic acid is an interesting topic in today's market prospects. This compound has potential applications in medicine, agrochemical and other fields.
    In the pharmaceutical industry, it may be a key intermediate for the creation of new drugs. Ceithiazole compounds often have diverse biological activities, such as antibacterial, anti-inflammatory, and anti-tumor. The unique structure of 4- (isopropyl) -1,3-thiazole-2-carboxylic acid may endow new drugs with novel mechanisms of action, bringing hope for the conquest of difficult diseases. Therefore, if a breakthrough can be made in drug research and development, its market demand will increase significantly.
    As for the agricultural field, such compounds may become important components of high-efficiency pesticides. With the increasing emphasis on the quality and environmental safety of agricultural products, it is urgent to develop green and high-efficiency pesticides. If 4 - (isopropyl) -1,3 - thiazole-2 - carboxylic acid can exhibit excellent insecticidal and bactericidal activities and is environmentally friendly, it will be able to win a place in the agricultural chemical market.
    However, looking at its market prospects, there are also challenges. The process of synthesizing this compound may need to be further optimized to reduce costs and yield. And before being introduced to the market, it must undergo strict safety evaluation and regulatory approval.
    Overall, 4- (isopropyl) -1,3-thiazole-2-carboxylic acids face challenges, but their potential applications in the fields of medicine and agrochemicals make them have considerable market prospects. Over time, they will surely emerge in related industries.