What is the chemical structure of 4-methylbenzothiazol-2-ylamine?

4-Methylbenzothiazol-2-ylamine is 4-methylbenzothiazol-2-amine, and its chemical structure is as follows.

This compound is composed of a benzothiazole parent nucleus, and benzothiazole is formed by fusing a benzene ring with a thiazole ring. There is an amino group (-NH _ 2) connected at the 2nd position of benzothiazole, and a methyl group (-CH 🥰) connected at the 4th position of benzothiazole.

From the perspective of atomic composition, it contains carbon (C), hydrogen (H), nitrogen (N), and sulfur (S) atoms. The benzene ring is composed of six carbon atoms, and the thiazole ring is composed of two carbon atoms, one nitrogen atom and one sulfur atom. The nitrogen atom in the amino group at position 2 is connected to the benzothiazole through covalent bonds, and the two hydrogen atoms of the amino group are connected to the nitrogen atom. The methyl group at position 4 is connected to the carbon atom at position 4 of the benzothiazole through a single carbon-carbon bond. The whole molecular structure endows 4-methylbenzothiazole-2-amine with specific physical and chemical properties, which has certain research and application value in organic synthesis and related fields.

What are the physical properties of 4-methylbenzothiazol-2-ylamine?

4-Methylbenzothiazole-2-ylamine, an organic compound, has unique physical properties and is quite useful in many fields.

Looking at its properties, it is mostly solid at room temperature, and its melting and boiling point is crucial to determine its stability and application scenarios. Scientifically determined, the melting point is about [X] ° C. At this temperature, a substance changes from a solid state to a liquid state, reflecting the strength of intermolecular forces. The boiling point is about [X] ° C, indicating that under a specific pressure, the energy required for a substance to transform from a liquid state to a gas state reveals its physical state at different temperatures.

Solubility is also an important property. In organic solvents, such as ethanol, dichloromethane, etc., it exhibits good solubility, because the molecular structure is similar to that of organic solvents. In water, the solubility is poor, because the molecular polarity matches the water molecule poorly.

The density of 4-methylbenzothiazole-2-ylamine is also characterized, about [X] g/cm ³. Compared with other common organic compounds, this density determines its distribution in the mixed system, which is of great significance for chemical separation and preparation processes.

In addition, its appearance is often white to light yellow powder or crystal, which is convenient for initial identification and differentiation.

In summary, the melting point, boiling point, solubility, density, and appearance of 4-methylbenzothiazole-2-ylamine together constitute its material properties, which lay the foundation for its application in chemical synthesis, materials science, drug development, and many other fields. In scientific research and industrial production, experiments and processes can be reasonably designed according to these properties to give full play to their effectiveness.

What are the main uses of 4-methylbenzothiazol-2-ylamine?

4-Methylbenzothiazole-2-amine is an organic compound with a wide range of uses.

In the field of medicinal chemistry, it is often used as a key intermediate. With its unique chemical structure, it can participate in many drug synthesis reactions and help build drug molecular structures with specific biological activities. Gain benzothiazole compounds often exhibit a variety of biological activities, such as antibacterial, anti-inflammatory, and anti-tumor. Using 4-methylbenzothiazole-2-amine as the starting material and modified by a series of chemical reactions, new antibacterial drugs may be developed to fight drug-resistant bacterial infections and escort human health.

In the field of materials science, it also has a good performance. It can be used to prepare functional materials, such as some organic optoelectronic materials. Due to the specific electronic structure and optical properties of the compound, it may endow the material with unique optoelectronic properties, such as improved luminous efficiency and improved charge transport performance. The resulting organic Light Emitting Diode (OLED) material may be applied to display technology, promoting the development of display devices to be thinner, higher resolution, and wide color gamut.

In the agricultural field, it may become a synthetic raw material for agricultural chemicals. Some compounds based on benzothiazole structures have inhibitory effects on crop diseases and insect pests. By means of structural modification and derivatization of 4-methylbenzothiazole-2-amine, high-efficiency, low-toxicity and environmentally friendly pesticides can be developed, which can help agricultural harvest and reduce negative impact on the ecological environment.

In short, 4-methylbenzothiazole-2-amine has important application value in many fields such as medicine, materials and agriculture due to its unique chemical structure, and has broad prospects.

What are 4-methylbenzothiazol-2-ylamine synthesis methods?

There are many ways to synthesize 4-methylbenzothiazole-2-amine in ancient times. First, it can be obtained through a clever substitution reaction through benzothiazole compounds as starting materials. First, take the appropriate benzothiazole, and under specific reaction conditions, react with the appropriate methylating reagent to introduce methyl at the fourth position of the benzothiazole ring to form the 4-methylbenzothiazole intermediate. Subsequently, the intermediate is reacted with an amino-containing reagent in a suitable reaction environment, and through complex chemical transformation, 4-methylbenzothiazole-2-amine can be obtained.

Furthermore, the benzothiazole ring can be gradually constructed from the basic organic raw materials and the target substituent can be introduced. For example, using o-aminophenol and ethyl acetoacetate as the starting materials, under appropriate catalyst and reaction conditions, the condensation reaction is first carried out to generate benzothiazole derivatives. This process requires precise control of the reaction temperature, time and proportion of the reactants to make the reaction proceed in the desired direction. Then, the resulting derivatives are further modified, and 4-methylbenzothiazole-2-amine is finally obtained through a series of reactions such as methylation and amination.

In addition, there are methods of catalysis by transition metals. Using halogenated aromatics containing suitable substituents and reagents containing sulfur and amino groups as raw materials, the construction of benzothiazole rings and the introduction of 4-methyl and 2-amino groups are achieved through cross-coupling and other reactions under the action of transition metal catalysts. This method requires the selection of appropriate transition metal catalysts, such as palladium, copper, etc., and their ligands to improve the selectivity and efficiency of the reaction, so as to effectively synthesize 4-methylbenzothiazole-2-amine. In short, the synthesis methods are diverse, each with its own advantages and disadvantages, and need to be carefully selected according to actual needs and conditions.

4-methylbenzothiazol-2-ylamine what are the precautions during use

4-Methylbenzothiazole-2-ylamine is an organic compound. During use, the following things should be paid attention to:
First, safety protection is essential. This compound may be toxic and irritating to a certain extent, and it can cause discomfort when it touches the skin, eyes or inhales its dust and vapor. Therefore, when using it, be sure to wear suitable protective equipment, such as laboratory clothes, gloves and protective glasses, to prevent direct contact. In case of inadvertent contact, rinse with plenty of water immediately and seek medical treatment according to the specific situation.
Second, the operating environment should be treated with caution. It should be operated in a well-ventilated place, and it is best to carry out related work in a fume hood, which can effectively avoid the accumulation of steam or dust in the air and reduce the risk of inhalation. At the same time, it should be kept away from fire and heat sources, because it may be flammable, in case of open flames, hot topics or cause combustion and explosion, so as to ensure the safety of the operating environment.
Third, storage conditions should not be ignored. It should be stored in a cool, dry and ventilated place, away from oxidants and acids. Because of its active chemical nature, contact with these substances, or cause chemical reactions, resulting in deterioration or danger. Storage containers must be well sealed to prevent leakage and moisture absorption.
Fourth, the code of use is indispensable. Before use, it is necessary to understand its chemical properties and reaction characteristics in detail, and conduct experiments or production in strict accordance with the operating procedures. When weighing and transferring, the action should be precise to avoid leakage. After use, the remaining reagents should also be properly disposed of and must not be discarded at will to prevent pollution to the environment.