4 Formyl 2 Methylthiazole
quinoline thiophene imidazole thiazole

4-Formyl-2-methylthiazole

    Specifications

    HS Code

    583205

    Chemical Formula C5H5NOS
    Molecular Weight 127.16 g/mol
    Appearance Yellow - orange liquid
    Boiling Point 198 - 200 °C
    Density 1.21 g/cm³
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Flash Point 83 °C
    Odor Pungent, characteristic odor
    Stability Stable under normal conditions

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    General Information
    Where to Buy 4-Formyl-2-methylthiazole in China?
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    Frequently Asked Questions

    As a leading 4-Formyl-2-methylthiazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 4-Formyl-2-methylthiazole?
    4-Formyl-2-methylthiazole is one of the organic compounds. Its physical properties, allow me to tell you in detail.
    Looking at its appearance, under room temperature and pressure, it is mostly colorless to light yellow liquid, and its appearance is very ordinary, but there is something hidden inside. This substance has a certain volatility, and in the air, it can slightly smell a special smell. This smell is neither fragrant nor foul. It is unique, as if it tells its unique chemical structure.
    When it comes to boiling point, it is about a specific temperature range, and this temperature is the key to maintaining its liquid-to-gas transformation. The melting point is another important physical parameter, and its value determines the physical form of this substance in a low temperature environment. 4-formyl-2-methylthiazole exhibits good solubility in organic solvents. Organic solvents such as common ethanol and ether can be fused with it, just like fish get water, forming a uniform and stable mixed system.
    In addition, its density is also a significant physical property. Compared with the density of water, there may be differences, and this difference affects its distribution in various liquid systems. And the stability of this substance to light and heat is also worthy of attention. Under light and high temperature, its chemical structure may change, which is covered by its physical properties.
    In summary, the physical properties of 4-formyl-2-methylthiazole are rich and diverse, and these many properties are intertwined, which together shape the unique position of this substance in the field of chemistry and are of great significance in many aspects such as organic synthesis and drug development.
    What are the chemical properties of 4-Formyl-2-methylthiazole?
    4-Formalyl-2-methylthiazole is an organic compound. It has unique chemical properties and has attracted much attention in the field of organic synthesis.
    This compound contains formyl (-CHO) and methylthiazolyl, which give it a variety of chemical activities. The presence of formyl groups makes it involved in many reactions, such as nucleophilic addition reactions. Nucleophiles can attack the carbonyl carbon of formyl groups, leading to a series of chemical transformations, which are commonly used in the construction of complex organic molecular structures.
    Furthermore, the 2-methylthiazole moiety is also affected. The thiazole ring has certain aromatic properties, stabilizes the molecular structure, and the introduction of methyl groups changes the distribution of molecular electron clouds, which affects the reaction activity and selectivity.
    4-formyl-2-methylthiazole In the condensation reaction, the formyl group can be condensed with compounds containing active hydrogen to form new carbon-carbon bonds or carbon-heteroatomic bonds, expanding the molecular skeleton. At the same time, it also shows performance in redox reactions. Formalyl groups can be oxidized to carboxyl groups or reduced to alcohol hydroxyl groups, and various transformations can be realized under different conditions and reagents.
    Due to its special chemical properties, 4-formyl-2-methylthiazole has potential applications in the fields of medicinal chemistry and materials science. In drug development, it can be used as a key intermediate to construct molecules with specific biological activities; in materials science, or because of its unique structure and reactivity, it participates in the creation of functional materials.
    What are the common synthetic methods of 4-Formyl-2-methylthiazole?
    4-Formalyl-2-methylthiazole is an important intermediate in organic synthesis. Its common synthesis methods are about the following numbers.
    First, it is obtained by formylation with 2-methylthiazole as the starting material. It is often formylated with Vilsmeier reagent composed of N, N-dimethylformamide (DMF) and phosphorus oxychloride (POCl). Among them, 2-methylthiazole reacts with Wellsmeier reagent at a suitable temperature to form an active intermediate first, and then through hydrolysis and other steps, 4-formyl-2-methylthiazole can be obtained. The advantage is that the reaction conditions are milder and the raw materials are relatively easy to obtain. However, it is necessary to pay attention to the corrosiveness and toxicity of the reagent during the operation, and the post-treatment may be more complicated.
    Second, it is synthesized by cyclization of compounds containing heteroatoms such as sulfur and nitrogen. For example, with a specific chain compound containing sulfur and nitrogen, under appropriate catalysts and reaction conditions, cyclization and formyl groups are introduced. This path requires careful design of the structure of the starting material, and the reaction conditions are strict, and the choice of catalyst is also critical, including its selectivity and yield of cyclization. But once successful, some tedious previous steps may be avoided, and more possibilities for structural modification of the product are provided.
    Third, thiazole derivatives are synthesized by functional group conversion. Thiazole derivatives with convertible functional groups are first prepared, and then the functional groups are converted into formyl groups through a series of reactions such as oxidation, reduction, and substitution. This process requires precise control of each step of the reaction to ensure the purity and yield of the target product.
    All these methods have their own advantages and disadvantages. When synthesizing, consider factors such as raw material cost, reaction conditions, yield and purity according to actual needs, and choose the best one to use, in order to obtain satisfactory results.
    4-Formyl-2-methylthiazole in what areas?
    4-Formyl-2-methylthiazole is one of the organic compounds. It is used in many fields and has a wide range of uses.
    In the field of medicine, it is often a key intermediate for the synthesis of drugs. Due to the special structure of the thiazole ring, it is endowed with unique chemical properties and biological activities. It can be chemically modified to create drug molecules with specific pharmacological effects. For example, in the development of antibacterial drugs, 4-formyl-2-methylthiazole can be reacted in a series to construct a core structure of antibacterial activity, which is beneficial for inhibiting bacterial growth and treating infectious diseases.
    In the field of materials science, it may participate in the preparation of functional materials. With its own structural characteristics, it can be used as a building block to assemble with other substances through specific reactions, giving the material special properties. For example, in optical materials, through clever design, the material may have unique photoluminescence and other properties, used for display, sensing and other aspects.
    In the fragrance industry, 4-formyl-2-methylthiazole also has a place. Because of its special smell, it can be used as one of the fragrance ingredients to prepare flavors and fragrances with unique aromas. It plays a role in enhancing the fragrance of food, cosmetics and other products, adding different flavors and aromas to products.
    In summary, 4-formyl-2-methylthiazole has developed its capabilities in the fields of medicine, materials science, and fragrances. With its unique structure and properties, it has contributed important forces to the development of various fields. It is an organic compound of great value.
    What is the market outlook for 4-Formyl-2-methylthiazole?
    4-Formyl-2-methylthiazole, this substance is in the market and has a promising future. It is unique in nature and has a wide range of uses. It can be traced in various fields of chemical industry.
    In the field of medicine, it is the key raw material for the synthesis of wonderful medicines. Many special drugs are made, relying on their participation to form unique structures, impart miraculous effects, and cannot be underestimated in the treatment of diseases.
    As for the field of materials, it also shows extraordinary power. It can help to develop new functional materials, such as those with specific photoelectric properties, for high-end electronic equipment, and contribute to the progress of science and technology.
    Furthermore, in the fine chemical industry, it is the cornerstone of the manufacture of special chemicals. The products produced in the fragrance, additive and other industries are all excellent, which can increase product quality and characteristics, and enhance market competitiveness.
    Its synthesis method has also become more and more refined. In the past, the process was complex and expensive, but now a new way has emerged, which has increased the yield and reduced the cost, paving the way for large-scale production. Therefore, the market supply is gradually abundant, the cost is controllable, and the demand is also rising.
    Even if the future is bright, there are challenges. The synthesis process or special reagents and conditions require strict adherence to safety regulations to ensure production safety. And the responsibility of environmental protection cannot be shirked. The development of green processes is a top priority.
    Overall, 4-formyl-2-methylthiazole has great potential in the market. If it can overcome the difficulties of technology and environmental protection, it will surely shine in various industries and expand its development.