4 Amino 2 Bromothiazole
quinoline thiophene imidazole thiazole

4-Amino-2-bromothiazole

    Specifications

    HS Code

    666314

    Chemical Formula C3H3BrN2S
    Molecular Weight 193.04
    Appearance Solid (usually a white to off - white powder)
    Melting Point Approximately 130 - 134 °C
    Solubility In Water Poorly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
    Odor Typically has a faint, characteristic odor
    Purity Can be available in various purity grades, e.g., 95%, 98%

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    General Information
    Where to Buy 4-Amino-2-bromothiazole in China?
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    Frequently Asked Questions

    As a leading 4-Amino-2-bromothiazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Amino-2-bromothiazole?
    4-Amino-2-bromothiazole is one of the organic compounds. It has a wide range of uses and is often a key raw material for traditional Chinese medicine in the field of medicinal chemistry.
    4-Amino-2-bromothiazole has a special chemical structure and activity, which can be used to create a variety of drugs. For example, in the research and development of antibacterial drugs, chemists can use chemical modification and other methods to construct molecular structures with specific antibacterial activities to deal with various bacterial infections.
    In the field of pesticide chemistry, it also has its uses. It can be used as an important intermediate for the synthesis of new pesticides. By combining with other chemical groups, it can create pesticide products that have high-efficiency killing or inhibitory effects on pests and are relatively friendly to the environment, which can help agricultural production.
    Furthermore, in the field of materials science, 4-amino-2-bromothiazole has also emerged. Due to its special chemical properties, it may be able to participate in the preparation of materials with special properties, such as some functional polymer materials. Chemists can use it to polymerize with other monomers to endow materials with special properties such as excellent electrical conductivity, optical properties or thermal stability, expanding the application range of materials.
    Overall, 4-amino-2-bromothiazole plays an important role in many fields such as medicine, pesticides and materials, providing a key chemical basis for the development of various fields, and promoting the progress and innovation of related science and technology.
    What are 4-Amino-2-bromothiazole synthesis methods?
    The synthesis method of 4-amino-2-bromothiazole has been explored by many scholars in the past, and now it is described.
    One method is often prepared by cyclization of sulfur-containing compounds with nitrogen and bromine-containing reagents. For example, appropriate thioamides are used to react with brominating reagents and ammonia sources under suitable conditions. Sulfur atoms in thioamides interact with brominating reagents to form bromine-containing intermediates, while ammonia sources provide amino groups. After intramolecular cyclization, thiazole rings are constructed, and 4-amino-2-bromothiazole is formed. In this process, the reaction conditions are very critical, and the choice of temperature and solvent affects the yield and purity of the product. If the temperature is too high, side reactions may increase; if the temperature is too low, the reaction rate will be slow. The solvent needs to have good solubility to the reactants and not interfere with the reaction process.
    There are also methods of using halogenated thiazole derivatives as starting materials. Halogenated thiazole and ammonia or ammonia derivatives undergo nucleophilic substitution in the presence of suitable catalysts. Halogen atoms are replaced by amino groups to obtain the target product 4-amino-2-bromothiazole. The type and dosage of catalysts have a great impact on the reaction. High-efficiency catalysts can speed up the reaction rate and improve product selectivity.
    In addition, there are methods of synthesizing by functional group conversion with thiazole ring as the parent body. First, thiazole containing suitable substituents is prepared, and then bromine atoms are introduced through bromination reaction, and then other substituents are converted into amino groups through appropriate reaction, so 4-amino-2-bromothiazole can also be obtained. This process step is relatively complicated, and the reaction of each step needs to be carefully controlled to ensure the quality of the product.
    All these synthesis methods have their own advantages and disadvantages, and must be carefully selected according to actual needs, such as raw material availability, cost, product purity requirements, etc., to obtain the ideal synthesis effect.
    What are the physical properties of 4-Amino-2-bromothiazole?
    4-Amino-2-bromothiazole is one of the organic compounds. Its physical properties are worth exploring.
    Looking at its properties, it is mostly solid at room temperature. Its color, or white to light yellow powder, is also recognizable among various chemical substances.
    The melting point is about a certain temperature range. This value is crucial for determining the purity of the substance and the physical changes under specific conditions. Due to the different purity of 4-amino-2-bromothiazole, its melting point may vary slightly.
    As for solubility, in common organic solvents, such as ethanol, dichloromethane, etc., it shows certain solubility characteristics. However, in water, its solubility is relatively limited. The difference in solubility is determined by the molecular structure of the compound. The chemical bonds within the molecule and the characteristics of functional groups make it interact with different solvent molecules differently, so it presents different solubility behaviors.
    Furthermore, its density is also an important physical property. The specific density value reflects the mass of the substance per unit volume, which is indispensable in many chemical experiments and industrial applications in terms of measurement and ratio. The physical properties of 4-amino-2-bromothiazole, such as color state, melting point, solubility, density, etc., are interrelated and have their own uses. They are all key factors to consider in the fields of chemical research and production practice.
    What is the market price of 4-Amino-2-bromothiazole?
    4-Amino-2-bromothiazole, the price of this product in the market is difficult to determine. Its price often changes due to many reasons, such as the supply and demand of the market, the amount of production, and the difficulty of making, all of which can affect its price.
    Looking at the market of chemical raw materials in the past, if the market demand is prosperous and the supply is small, the price will rise; if the production is wide and the demand is thin, the price will often be depressed. If 4-amino-2-bromothiazole is used in the production of various fine chemicals or in the process of pharmaceutical research and development, when related industries are booming, the demand will increase sharply, and its price will rise accordingly.
    Furthermore, the difficulty of preparation is also the main reason. If the production method is complicated, the raw materials are rare, or special conditions and processes are required in the production, the cost is high and the price is not cheap. On the contrary, if the preparation is convenient, the raw materials are easy to find, and the cost is controllable, the price should be stable or lower.
    However, I do not have the exact past price data, so it is difficult to specify the specific price in the market. For details, you can consult the chemical product trading market, the merchants specializing in this product, or the chemical industry information platform to get the current and accurate price.
    4-Amino-2-bromothiazole in what areas?
    4-Amino-2-bromothiazole is useful in the fields of medicine, pesticides, and materials.
    In the field of medicine, this compound can be a key intermediate for the creation of new drugs. Due to its unique structure, potential biological activity, it can be combined with specific biological targets. It can be used to develop antibacterial drugs to deal with the increasingly serious problem of bacterial resistance; or in the exploration of anti-tumor drugs, its structural properties interfere with the growth and proliferation pathways of tumor cells, contributing to the solution of cancer problems.
    In the field of pesticides, 4-amino-2-bromothiazole can be used as a raw material for the creation of high-efficiency and low-toxicity pesticides. After rational design and modification, it can develop pesticides that target specific pests or diseases, improve the yield and quality of crops, and have little impact on the environment, which is in line with the current development needs of green agriculture.
    In the field of materials, it can participate in the preparation of functional materials. Because of its special chemical structure, or endow materials with specific properties such as fluorescence and conductivity. It can be used to make organic Light Emitting Diode (OLED) materials to improve the performance of display technology; or in the research and development of sensor materials, with its sensitive response to specific substances, to achieve rapid and accurate detection of environmental pollutants, biomolecules, etc.
    In summary, although 4-amino-2-bromothiazole is a chemical substance, it plays an important role in many fields and has broad prospects. It is a key component that many scientific research and industrial development rely on.