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What are the main uses of 4,5,6,7-tetrahydrobenzothiazole-2,6-diamine?
4,5,6,7-tetrahydrophenylindole-2,6-dione, which is widely used in the field of medicine and materials science.
In the field of medicine, it exhibits unique biological activity and may become a key intermediate for drug development. Due to its unique molecular structure, it has the potential to interact with specific biological targets. For example, it has been found that some compounds containing 4,5,6,7-tetrahydrophenylindole-2,6-dione structure have inhibitory effects on the growth of tumor cells. It can interfere with the signal transduction pathway of tumor cells, block the proliferation of tumor cells, and even induce their apoptosis. Some studies have also shown that these compounds have potential therapeutic effects on neurological diseases, such as Alzheimer's disease, or can regulate protein expression and metabolism in the nervous system and improve neural function.
In the field of materials science, 4,5,6,7-tetrahydrophenylindole-2,6-dione also has extraordinary performance. Due to its special electronic structure and optical properties, it has great potential in organic optoelectronic materials. It can be used to prepare organic Light Emitting Diode (OLED) to improve the luminous efficiency and stability of the device. Because its molecular structure can regulate the luminous color, it can meet different display needs. In solar cell materials, it can also optimize charge transfer and conversion efficiency, enhance the performance of solar cells, and provide a new direction for the development of new energy materials.
What are the physical properties of 4,5,6,7-tetrahydrobenzothiazole-2,6-diamine
The physical properties of 4,5,6,7-tetrahydrobenzopyran-2,6-diol are as follows:
This compound is in a crystalline state at room temperature and has a certain melting point. Due to the presence of polar groups such as hydroxyl groups in the molecule, it has a certain solubility in water. Its hydroxyl groups can participate in the formation of hydrogen bonds, resulting in higher melting points and boiling points than similar structural compounds without such polar groups. And because its molecules have a specific spatial configuration and electron cloud distribution, they also have different solubility in organic solvents.
Looking at its molecular structure, the benzopyran ring gives it a certain rigidity and stability, while the diol group increases the polarity of the molecule. This polarity increases the force between it and the polar solvent molecules, and can form hydrogen bonds with water molecules in water. However, the solubility is also affected by the overall size of the molecule and the hydrophobic part.
When it comes to appearance, it is often a white or nearly white crystalline solid, which is caused by the orderly arrangement of molecules and the scattering properties of light. Its density is also related to the degree of molecular packing, and the closely packed crystal structure makes the density relatively high.
In addition, the compound has a certain flexibility due to the inclusion of multiple rotatable chemical bonds, but the rigidity of the benzopyran ring limits some of its conformational changes. This structural feature also has an important impact on its physical properties.
What are the chemical properties of 4,5,6,7-tetrahydrobenzothiazole-2,6-diamine?
4,5,6,7-tetrahydrobenzofuran-2,6-dione is also an organic compound. Its chemical properties are unique and valuable to explore.
This compound contains furan rings and diketone structures, so it exhibits specific chemical activities. In terms of reactivity, its carbonyl moiety is electrophilic and can react with nucleophiles. For example, it can condensate with alcohols under suitable conditions to generate corresponding ketal derivatives. This reaction is often a key step in the construction of complex structures in organic synthesis.
Furthermore, the conjugate system of the compound also affects its properties. The conjugate structure endows it with certain stability and also makes it unique in spectral properties. In the UV-visible spectrum, there may be specific absorption peaks, which can be used for identification and quantitative analysis.
In addition, its stereochemical characteristics cannot be ignored. The spatial configuration of the molecule may affect its reaction selectivity and biological activity. If the molecule exists in a chiral center, the behavior of different isomers in chemical reactions and organisms may be very different.
In the field of organic synthesis, 4,5,6,7-tetrahydrobenzofuran-2,6-dione is often an important synthetic intermediate. By modifying and derivatization of its structure, a variety of organic molecules with biological activity or special functions can be prepared, which have potential applications in drug development, materials science and other fields.
What are the synthesis methods of 4,5,6,7-tetrahydrobenzothiazole-2,6-diamine?
The synthesis method of 4,5,6,7-tetrahydroquinopyridine-2,6-dione can be done according to the ancient method, with exquisite skills and steps.
First take suitable starting materials, such as aromatic compounds with specific substituents, which are the basis for synthesis. In the clean kettle, use alcohol as a solvent, add an appropriate amount of alkali, such as potassium carbonate, which can adjust the acid-base of the reaction and promote the progress of the reaction. Warm up to an appropriate degree, about 60-80 degrees Celsius, continue to stir, so that the raw materials are evenly mixed and interact. At this time, the raw material molecules follow the laws of chemistry, and condensation reactions gradually occur.
After the reaction has been carried out for a certain period of time, observe the reaction process by thin layer chromatography. If the raw material point gradually fades, the product point gradually becomes apparent and stabilizes, it can be seen that the reaction is nearly complete. Then, the reaction solution is cooled to room temperature, poured into an appropriate amount of water, extracted with an organic solvent, such as ethyl acetate, and extracted several times to enrich the product in the organic phase. Then dry the organic phase with anhydrous sodium sulfate to remove the moisture.
After that, distillation under reduced pressure to remove the organic solvent to obtain a crude product. The crude product is refined by column chromatography, and a suitable silica gel and eluent, such as petroleum ether and ethyl acetate, are mixed in a specific ratio to separate the product from impurities. With careful operation, the eluent containing the pure product is collected and the solvent is evaporated to obtain a pure 4,5,6,7-tetrahydroquinopyridine-2,6-dione.
Or according to the other method, aldodes, amines and dicarbonyl compounds are used as starting materials, and heated and refluxed in an organic solvent in the presence of an acidic catalyst, such as p-toluenesulfonic acid. During the reaction, the raw materials are condensed and cyclized with each other, and can also form this target product. After the reaction, the subsequent treatment is similar to the previous method. After extraction, drying, distillation, column chromatography and other steps, high purity can be obtained.
This method of synthesis requires the operator to be cautious, familiar with the principles of chemistry and reaction, and follow the order in order to obtain the desired result.
What is the price range of 4,5,6,7-tetrahydrobenzothiazole-2,6-diamine in the market?
The price range of 4,5,6,7-tetrahydroquinopyridine-2,6-dione in the market is difficult to say exactly. The price is influenced by many factors, such as the quality of the goods, the simplicity of the production, the state of supply and demand, and the market conditions are fickle, and the price fluctuates accordingly.
If the quality is good and the production is exquisite, the price may be slightly higher; if the supply exceeds the demand, the price may drop; if the supply is in short supply, the price may rise. Furthermore, the price varies when purchased in different places and at different times.
If you want to get the exact price, you can go to the pharmaceutical store, the chemical raw material market, and consult the merchants; or in the electronic commerce platform, check the price. In this way, we can get close to the actual price.