4 2 Cyclopentylethyl 2 Methylthiazole 5 Carboxylic Acid
quinoline thiophene imidazole thiazole

4-(2-cyclopentylethyl)-2-methylthiazole-5-carboxylic acid

    Specifications

    HS Code

    874830

    Chemical Formula C12H17NO2S
    Molecular Weight 239.334 g/mol
    Iupac Name 4-(2-cyclopentylethyl)-2-methyl-1,3-thiazole-5-carboxylic acid
    Appearance Solid (predicted)
    Boiling Point Predicted around 388.6 °C at 760 mmHg
    Solubility In Water Low solubility (due to non - polar cyclopentyl and thiazole moieties)
    Logp Predicted to be relatively high (hydrophobic nature)
    Pka Predicted around 4 - 5 (carboxylic acid group)
    Flash Point Predicted around 188.8 °C

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    General Information
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    Frequently Asked Questions

    As a leading 4-(2-cyclopentylethyl)-2-methylthiazole-5-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 4- (2-cyclopentylethyl) -2-methylthiazole-5-carboxylic acid?
    This is the problem of the chemical structure of 4- (2-cyclopentyl ethyl) - 2-methylthiazole-5-carboxylic acid. Looking at this designation, its structure can be deduced according to the method of organic chemical structure analysis.
    "4- (2-cyclopentyl ethyl) ", which indicates that a substituent is connected at a specific position (position 4) of the main structure, and this substituent is 2-cyclopentyl ethyl. The cyclopentyl group is a ring structure composed of five carbon atoms, and "2-cyclopentylethyl" means that the cyclopentyl group is connected to the second position of the ethyl group, which is then connected to the fourth position of the main structure.
    "2-methylthiazole", indicating that the main structure is a thiazole ring, which is a five-membered heterocycle containing sulfur and nitrogen, and has methyl substitution at the second position.
    "5-carboxylic acid" means that the fifth position of the thiazole ring is connected with a carboxyl group (-COOH).
    In summary, the structure of this compound is a thiazole ring as the core, with methyl at position 2, 2-cyclopentyl ethyl at position 4, and carboxyl at position 5. Therefore, the chemical structure of this 4- (2-cyclopentyl ethyl) -2-methylthiazole-5-carboxylic acid is clear.
    What are the physical properties of 4- (2-cyclopentylethyl) -2-methylthiazole-5-carboxylic acid
    4- (2-cyclopentyl ethyl) - 2-methylthiazole-5-carboxylic acid, this is an organic compound. It has some unique physical properties.
    Looking at its properties, it may be in a solid state at room temperature and pressure, but the exact state also depends on the purity and environmental conditions. As for the color, when it is pure, it may be white to off-white powder. If it contains impurities, the color may be deviated.
    When it comes to melting point, this is an important physical constant of the compound. After measurement and experiment, its melting point is in a certain temperature range, but I don't have the exact value at hand. The determination of the melting point is of great significance in the identification and purity determination, which can help chemists to distinguish its authenticity and purity.
    In terms of solubility, it is crucial to the performance of organic solvents. Generally speaking, it may have a certain solubility in common organic solvents, such as ethanol and acetone. Due to the principle of similarity and miscibility, the structural characteristics of this compound make it have a good affinity with some organic solvents. The solubility in water is poor or poor, because its molecular structure contains hydrophobic groups, making it difficult to dissolve in water with strong polarity.
    In addition, the density of this compound is also one of the physical properties. Although the exact density value is not yet known, it can be speculated from its structure and similar compounds that its density may be similar to that of common organic solids. Density has an impact on chemical production, storage and transportation, and is related to product quality and safety.
    The physical properties of this 4- (2-cyclopentyl ethyl) -2-methylthiazole-5-carboxylic acid are of great significance in chemical research, chemical production and related fields. It helps researchers understand its characteristics for subsequent operation and exploration.
    What is the main use of 4- (2-cyclopentylethyl) -2-methylthiazole-5-carboxylic acid?
    4- (2-cyclopentyl ethyl) -2-methylthiazole-5-carboxylic acid is of great value in various applications. It has significant functions in the field of medicine. Due to its special chemical structure, it can be used as a key intermediate in pharmaceutical synthesis. Based on this, a variety of bioactive compounds can be prepared, or it can be used to develop drugs for the treatment of specific diseases, such as certain inflammation-related diseases, because it may have the potential to regulate inflammatory reactions in the body.
    In the field of pesticides, it is also possible. It can be reasonably modified to have insecticidal and bactericidal properties. By interfering with the physiological process of pests or pathogens, the purpose of controlling pests and diseases is achieved, and the growth and yield of crops are guaranteed.
    In the field of materials science, there are also potential uses. Due to its unique molecular structure, it may participate in the synthesis of special materials. It may endow materials with specific physical and chemical properties, such as improving the stability and solubility of materials, and then be used to develop new functional materials, which may have room for development in electronic and optical materials.
    To sum up, 4- (2-cyclopentyl ethyl) -2-methylthiazole-5-carboxylic acid has great potential in many fields such as medicine, pesticides and materials science. It has a wide range of uses and promising prospects.
    What are the synthesis methods of 4- (2-cyclopentylethyl) -2-methylthiazole-5-carboxylic acid
    To prepare 4- (2-cyclopentylethyl) -2-methylthiazole-5-carboxylic acid, there are many methods, and each has its advantages and disadvantages, which are described in detail below.
    First, it can be started from raw materials containing thiazole rings. Choose a suitable 2-methylthiazole-5-carboxylic acid derivative to react with 2-cyclopentylethylation reagents under suitable conditions. Common ethylation reagents, such as halogenated hydrocarbons, such as 2-cyclopentyl bromoethane. During the reaction, a base is required as a catalyst, such as potassium carbonate, sodium carbonate, etc., in an organic solvent, such as N, N-dimethylformamide (DMF), acetonitrile, heated and stirred, and the target product is expected to be obtained through nucleophilic substitution reaction. The raw materials of this route are relatively easy to obtain, and the reaction conditions are relatively mild. However, selective or need attention to prevent side reactions, such as the formation of multiple substitution products.
    Second, the strategy is to construct a thiazole ring. Take sulfur-containing compounds, carbonyl compounds and ammonia sources, and construct a thiazole ring through condensation reaction. If 2-cyclopentyl acetoacetate ethyl ester, thiourea and formaldehyde are used as raw materials, under acidic or basic catalysis, the thiazole ring skeleton is first formed, and then hydrolysis and acidification steps are carried out to obtain the target carboxylic acid. This route is simple in raw materials, cost or low, but the reaction steps are slightly more, and the overall yield may be affected.
    Third, the coupling reaction catalyzed by transition metals. Select thiazole ring halide, such as 4-halo-2-methylthiazole-5-carboxylic acid, and 2-cyclopentyl ethylboronic acid or borate, react in an organic solvent in the presence of transition metal catalysts such as palladium catalysts, ligands and bases. This method has good selectivity and high reaction efficiency, but the cost of transition metal catalysts is high, and the post-reaction treatment is more complicated, which requires the removal of metal residues.
    The above methods are all feasible paths for the synthesis of 4- (2-cyclopentyl ethyl) -2 -methylthiazole-5 -carboxylic acid. In actual operation, it is necessary to comprehensively consider factors such as raw material availability, cost, yield and purity requirements, and make a prudent choice.
    What is the price range of 4- (2-cyclopentylethyl) -2-methylthiazole-5-carboxylic acid in the market?
    4 - (2 -cyclopentyl ethyl) - 2 -methylthiazole-5 -carboxylic acid, this product is in the market, its price is uncertain, due to many reasons.
    Looking at the past, the price of chemical materials was often around supply and demand. If there are many people seeking this product, but there are few producers, the price will rise; conversely, if the supply exceeds demand, the price may decline. And the difficulty of its preparation is also related to its price. If the preparation method is complicated, requires a variety of raw materials, time-consuming and laborious, the cost will be high, and the price will also rise; if the preparation is simple, the price may be close to the people.
    Furthermore, the price of raw materials is also a major factor. If the price of raw materials required for the synthesis of this acid is high, or due to the scarcity of raw materials and the difficulty of harvesting, the price of the finished product will increase. Different origins also have an impact. Different places have different production costs and transportation costs, resulting in different prices of this product in different places.
    In addition, the state of market competition also affects its price. If there are many similar or replaceable products in the market, various merchants compete for the market, or reduce their prices to attract customers; if there are no competing products, the price may rise steadily.
    After checking the records of past market conditions, it is difficult to determine the scope of its price. However, according to common sense, its price may fluctuate within a larger range due to the above factors, ranging from a few hundred yuan per gram to several thousand yuan per gram.