3 Methylisothiazole 4 Carboxylic Acid
quinoline thiophene imidazole thiazole

3-Methylisothiazole-4-carboxylic acid

    Specifications

    HS Code

    268949

    Chemical Formula C5H5NO2S
    Molar Mass 143.164 g/mol
    Appearance White to off - white solid
    Solubility In Water Moderately soluble
    Boiling Point Decomposes before boiling
    Melting Point 162 - 164 °C
    Pka Value Around 2.7
    Odor Faint, characteristic
    Density N/A (usually measured in solid form with irregular shape)
    Stability Stable under normal conditions, but sensitive to strong acids and bases

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    General Information
    Where to Buy 3-Methylisothiazole-4-carboxylic acid in China?
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    Frequently Asked Questions

    As a leading 3-Methylisothiazole-4-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-Methylisothiazole-4-carboxylic acid?
    3-Methylisothiazole-4-carboxylic acid, this substance has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help synthesize many drugs with special curative effects. For example, in the creation of antibacterial drugs, with its unique chemical structure, it can give drugs more ideal antibacterial activity and targeting, and help to overcome the problem of specific bacterial infections.
    In the field of pesticides, it also plays a pivotal role. As an important raw material for pesticide synthesis, high-efficiency and low-toxicity pesticide products can be synthesized. Such pesticides can accurately act on pests, have good control effects on crop pests, pathogens, etc., and reduce the harm to the environment, which is in line with the current needs of green agriculture development.
    In addition, in the field of materials science, 3-methylisothiazole-4-carboxylic acids can be involved in the preparation of functional materials. For example, it is used to synthesize polymer materials with special properties, which may exhibit excellent properties in corrosion resistance, stability, etc., and thus be applied in fields such as protective coatings for chemical equipment and plastics used in special environments. Its chemical properties can improve the structure and properties of materials to meet the diverse needs of industrial production and practical applications.
    What are the synthetic methods of 3-Methylisothiazole-4-carboxylic acid?
    The synthesis methods of 3-methyl isothiazole-4-carboxylic acid have been used throughout the ages, and there are various paths.
    First, the structure of the compound can be gradually constructed by using sulfur-containing and nitrogen-containing compounds as starting materials through delicate steps such as condensation and cyclization. The initial raw materials react with each other, such as sulfur atoms and nitrogen atoms cleverly connected to construct the core ring system of isothiazole. In this process, the reaction conditions such as temperature, pH and reaction time need to be carefully regulated. Too high or too low temperature may lead to over-reaction or under-reaction, and pH imbalance will also affect the reaction process and product purity.
    Second, there is also a specific carboxylic acid derivative as the starting point, which is achieved by introducing methyl groups and constructing isothiazole rings. The structure of the carboxylic acid derivative is first modified, and then the methyl groups are precisely integrated through suitable reaction conditions, and then the isothiazole ring is formed by cyclization reaction. This path requires a precise grasp of the reagent selection and reaction sequence of each reaction step in order to obtain the ideal yield and purity.
    Third, there is a method, which is based on heterocyclic compounds and obtained by functional group transformation. The specific positions of the existing heterocyclic rings are modified to gradually convert the functional groups into the desired 3-methylisothiazole-4-carboxylic acid structure. In this process, the choice of catalyst is particularly critical, which can significantly affect the reaction rate and selectivity, and efficient catalysts can promote the smooth progress of the reaction towards the target product.
    All these synthesis methods require chemists to carefully operate, strictly control, weigh the advantages and disadvantages of each method, and choose carefully according to actual needs and conditions to achieve efficient and high-quality synthesis of 3-methylisothiazole-4-carboxylic acid.
    What are the physical and chemical properties of 3-Methylisothiazole-4-carboxylic acid?
    3-Methylisothiazole-4-carboxylic acid, this is an organic compound. Its physical and chemical properties are unique, let me talk about them one by one.
    Looking at its appearance, it is often white to light yellow crystalline powder, which is visually visible to the naked eye. It is stable at room temperature and pressure, and will change under specific conditions.
    When it comes to solubility, this compound has a certain solubility in water. Because the carboxyl group contained in the molecular structure can form hydrogen bonds with water molecules, it can be dispersed to a certain extent in water. However, its solubility is not infinite, and is restricted by factors such as temperature and solvent polarity. When the temperature increases, the solubility may increase; if the polarity of the solvent is better matched with the structure of the compound, its solubility will also be improved.
    Its melting point is also an important physical property. After experimental determination, there is a specific melting point range, which is one of the important basis for identifying the compound. When heated to the melting point temperature, the substance changes from solid to liquid, and the change of the physical state can be clearly observed.
    In terms of chemical properties, the presence of carboxyl groups endows it with acidity. It can neutralize with bases to generate corresponding salts. This reaction has a wide range of uses in organic synthesis, and can be used to prepare different derivatives. And the structure of the isothiazole ring makes it have certain reactivity and can participate in a variety of organic reactions, such as nucleophilic substitution reactions. Due to the electron cloud distribution and bond energy characteristics of atoms on the ring, specific reagents can attack specific positions on the ring to achieve structural modification and transformation.
    The physicochemical properties of 3-methylisothiazole-4-carboxylic acids are of great significance in organic synthesis, medicinal chemistry and other fields, laying a foundation for related research and applications.
    What is the price range of 3-Methylisothiazole-4-carboxylic acid in the market?
    The price range of 3-methylisothiazole-4-carboxylic acid in the market is difficult to determine. Due to changing market conditions, its price is always affected by various factors.
    If we take the past as an example, the abundance of raw materials is a big obstacle. If the raw materials required for its preparation are abundant, the price may be leveled; if the raw materials are scarce, the price will rise.
    The production technology is also the key. If the new technology is released, the yield will increase and the cost will decrease, and the price will also change. Furthermore, the amount of demand can also move the price. If the market demand for this product is strong, the supply is in short supply, and the price may rise; if the demand is weak, the supply exceeds the demand, and the price will drop.
    According to the market in previous years, the price per gram may be between a few yuan and a few tens of yuan. However, this is only a rough number, not a definite one. The market is impermanent, and if you want to know the real-time price, you should consult the merchants specializing in chemical products, or the platforms that observe the trading of chemical products, to be sure.
    What are the storage conditions for 3-Methylisothiazole-4-carboxylic acid?
    3-Methylisothiazole-4-carboxylic acid, this is a fine chemical. Its storage conditions are very critical, related to its quality and stability.
    It should be placed in a cool place, because heat is easy to cause its properties to change. It is necessary to choose a well-ventilated place to prevent the accumulation of harmful gases and damage to its quality. Humidity also needs to be strictly controlled. If it is too wet, or it is subject to moisture and deterioration, it should be stored in a dry place.
    And it should be kept away from fire and heat sources. This chemical may be flammable and dangerous when exposed to open flames and hot topics. It needs to be stored separately from oxidizing agents, acids, alkalis, etc. Because of its active chemical properties, it can be mixed with other substances or react chemically, which poses a risk of safety.
    When choosing a storage container, it should be well sealed to prevent leakage, and it is easy to access and manage. For warehouse management, a special person should be responsible for regular inspection and detailed storage conditions. When handling, it should also be handled with care to avoid package damage. In this way, the safety and quality of 3-methylisothiazole-4-carboxylic acid can be guaranteed during storage.