3 Methyl 5 Benzoylaminoisothiazole 4 Carboxylic Acid P Chlorophenylamide
quinoline thiophene imidazole thiazole

3-Methyl-5-benzoylaminoisothiazole-4-carboxylic acid p-chlorophenylamide

    Specifications

    HS Code

    424544

    Chemical Formula C20H16ClN3O3S
    Molecular Weight 413.878 g/mol
    Appearance Solid (likely, based on common amide compounds)
    Solubility In Water Low (due to non - polar benzene and isothiazole rings)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (due to non - polar nature of the molecule)
    Melting Point Needs experimental determination (no general value available without specific data)
    Boiling Point Needs experimental determination (no general value available without specific data)
    Pka No general value available without specific data (acidic group is carboxylic acid, but pKa affected by other groups in molecule)
    Density Needs experimental determination (no general value available without specific data)
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

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    General Information
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    Frequently Asked Questions

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    What is the chemical structure of 3-Methyl-5-benzoylaminoisothiazole-4-carboxylic acid p-chlorophenylamide?
    3-Methyl-5-benzoylamino isothiazole-4-carboxylic acid p-chlorobenzamide, this is an organic compound. Looking at its name, it can be seen that it is composed of several parts of the structure.
    The first word is "isothiazole", which is a five-membered heterocyclic ring containing sulfur and nitrogen atoms. It is connected to a methyl group at the 3rd position and a benzoylamino group at the 5th position. The so-called benzoylamino group is the structure in which the benzoyl group is connected to an amino group.
    Looking at the "4-carboxylic acid p-chlorobenzamide" part again, it shows that the 4-position of the isothiazole ring is connected with a carboxylic acid structure, and the carboxylic acid reacts with p-chloroaniline to form a p-chlorobenzamide structure. P-chlorobenzamide, that is, p-chlorophenyl is connected to an amide group.
    Its overall structure is schematically as follows: With the isothiazole ring as the core, the 3-position pendant methyl group, the 5-position pendant benzoamide group, and the 4-position carboxylic group is connected to the p-chlorobenzamide structure, thus forming the chemical structure of the 3-methyl-5-benzoam
    What are the main uses of 3-Methyl-5-benzoylaminoisothiazole-4-carboxylic acid p-chlorophenylamide
    3-Methyl-5-benzoamidoisothiazole-4-carboxylic acid-p-chlorobenzamide, an organic compound. It has a wide range of uses and is often an important intermediate in drug synthesis in the field of medicine. Through specific chemical reactions, it can be integrated into various drug molecular structures, laying the foundation for the creation of drugs with specific therapeutic effects, or used to develop antibacterial and anti-inflammatory drugs.
    In the field of pesticides, it is also used. It can be used as a key raw material for the synthesis of new pesticides, giving pesticides unique biological activities, such as insecticidal and bactericidal properties, helping to improve crop yield and quality, and reducing the damage of pests and diseases to crops. < Br >
    In the field of materials science, it may also show some uses. It may be able to participate in the synthesis of functional materials, giving materials such as special optical and electrical properties, so as to meet the needs of different fields for special materials. In short, the compound plays an important role in the research and production practice of many fields, and contributes to the promotion of technological progress and innovation in related fields.
    What is the synthesis method of 3-Methyl-5-benzoylaminoisothiazole-4-carboxylic acid p-chlorophenylamide
    To prepare 3-methyl-5-benzoamidoisothiazole-4-carboxylic acid-p-chlorobenzamide, the following method can be used.
    First, a suitable starting material, such as a compound containing isothiazole structure, is reacted with a reagent with a specific substituent. Those containing 3-methyl-5-aminoisothiazole-4-carboxylic acid structure are often selected as starting materials.
    First, this starting material is reacted with benzoyl chloride. In a suitable reaction solvent, such as dichloromethane or N, N-dimethylformamide, add an appropriate amount of acid binding agent, such as triethylamine or pyridine. After stirring at low temperature to room temperature, the amino group undergoes nucleophilic substitution with benzoyl chloride to obtain 3-methyl-5-benzoamidoisothiazole-4-carboxylic acid.
    This product is then reacted with p-chloroaniline to produce an amide. This product is often assisted by a condensing agent, such as dicyclohexyl carbodiimide (DCC) or 1 - (3-dimethylaminopropyl) - 3 - ethyl carbodiimide hydrochloride (EDC · HCl), and the catalyst is added 4-dimethylaminopyridine (DMAP). React in suitable solvents, such as dichloromethane or tetrahydrofuran, at room temperature to moderate warming conditions. The condensing agent activates the carboxyl group to undergo nucleophilic substitution with the amino group of p-chloroaniline. After reaction, separation and purification, 3-methyl-5-benzoylamino isothiazole-4-carboxylic acid p-chlorobenzamide can be obtained.
    The whole process needs to pay attention to the precise control of the reaction conditions. Each step of the product is monitored and identified by means such as thin layer chromatography, nuclear magnetic resonance, mass spectrometry, etc., to ensure the smooth reaction and the purity of the product.
    What are the physical and chemical properties of 3-Methyl-5-benzoylaminoisothiazole-4-carboxylic acid p-chlorophenylamide
    The physicochemical properties of 3-methyl-5-benzoamidoisothiazole-4-carboxylic acid p-chlorobenamide are particularly important. Looking at its properties, under room temperature, or white to off-white powder, the texture is fine, which is the appearance that can be observed by the eye.
    When it comes to solubility, in common organic solvents, its performance varies. In dichloromethane, it is quite soluble, just like the water of fish, and the two are in perfect harmony; in methanol, it also has a certain solubility, although it does not reach a completely miscible state, it can be partially dispersed. However, in water, the solubility is very small, just like oil floats on the water surface, and it is difficult to merge with the water phase. This is because of the characteristics of its molecular structure, which contains many hydrophobic groups, resulting in poor hydrophilicity.
    Then again, the melting point, after fine determination, is about a specific temperature range. This temperature range is the critical range for the substance to change from solid to liquid. Accurate determination of the melting point is of great significance in identification and purity judgment.
    In terms of stability, under conventional environmental conditions, it is quite stable and can maintain its own structure and properties for a long time. However, if placed in an extreme environment of high temperature, high humidity, or strong acid and alkali, its structure may change, and chemical reactions will occur, causing its properties to change. For example, when encountering strong acids, some chemical bonds in their molecules may be destroyed, causing structural rearrangement; in strong alkali environments, reactions such as hydrolysis may also occur, resulting in loss of original chemical properties. These are all important points that cannot be ignored when considering the physical and chemical properties of the substance.
    3-Methyl-5-benzoylaminoisothiazole-4-carboxylic acid p-chlorophenylamide market prospects
    3-Methyl-5-benzoamidoisothiazole-4-carboxylic acid-p-chlorobenzamide, the current market prospect of this product is like a fog to be revealed, and it needs to be investigated urgently.
    Looking at the rise and fall of chemical products in the past, it can be seen that the market prospect often depends on multiple ends. First of all, if there is a strong demand for it in the fields of medicine, pesticides, etc., the market road will be open. This compound may have unique uses in the development of new drugs. If it can become a key intermediate and add wings to pharmaceutical innovation, it will attract pharmaceutical companies and the market prospect will be bright.
    Times and competition. Today's chemical market, a hundred schools of thought contend. If there are alternatives with similar effects elsewhere, and the cost is low and the process is simple, the competitive pressure will increase sharply. On the contrary, if its synthesis process is unique, the quality is excellent, and it is difficult to have competing products, it is easy to take the top spot in the market.
    Furthermore, policies and regulations. In the chemical industry, the supervision is very strict. If production compliance is in line with new policies such as environmental protection, it can stabilize the trend; conversely, it may be limited by new regulations and the market will be frustrated.
    Technological innovation should not be ignored. With the increasing technology, the improvement of synthesis methods may reduce costs and increase efficiency, enhance product competitiveness, and expand the market territory; conversely, if it rests on its laurels, the technology lags behind and may be abandoned by the market.
    Although it is difficult to determine what its market prospects are at the moment, a closer look at the context of demand, competition, policy, technology, etc., may gradually reveal its direction in the market.