3 Bromoisothiazole
quinoline thiophene imidazole thiazole

3-Bromoisothiazole

    Specifications

    HS Code

    871023

    Name 3 - Bromoisothiazole
    Molecular Formula C3H2BrNS
    Molecular Weight 162.02 g/mol
    Appearance Colorless to light yellow liquid or solid
    Boiling Point 198 - 200 °C
    Melting Point 34 - 37 °C
    Density 1.81 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Flash Point 82.3 °C
    Pungent Odor Yes
    Cas Number 19198 - 88 - 8

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    General Information
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    Frequently Asked Questions

    As a leading 3-Bromoisothiazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of Bromoisothiazole?
    3-Bromoisothiazole, this is an organic compound. Its chemical properties are unique and interesting.
    When it comes to physical properties, it is usually in a solid state, but the specific melting point and boiling point of the genus vary depending on environmental factors. Its appearance may be white to light yellow powder or crystal, and its texture is fine.
    In terms of chemical activity, the presence of bromine atoms in this compound gives it significant characteristics. Bromine atoms are quite active and can often play an important role in chemical reactions. Because of their electronegativity and atomic radius, they are prone to participate in nucleophilic substitution reactions. When encountering nucleophilic reagents, bromine atoms are like fuzes ignited, triggering substitution changes. Nucleophiles such as alcohols and amines can interact with bromine atoms in 3-bromo isothiazole, and then derive new compounds with different structures.
    isothiazole ring is also not an ordinary generation. Its ring structure is rich in electrons and has a certain aroma, which makes it possible to participate in many reactions involving electron transfer. For example, in some redox reactions, isothiazole rings may undergo wonderful changes due to changes in electron cloud density.
    and 3-bromo isothiazole are very useful in the field of organic synthesis. Due to its unique chemical properties, it is often regarded as a key synthetic building block, like the cornerstone of building a tall building. By ingeniously designing and manipulating their reaction pathways, chemists have been able to build complex and functional organic molecules, which have contributed to the development of medicine, materials, and many other fields.
    What are the physical properties of Bromoisothiazole?
    3 - Bromoisothiazole is an organic compound with unique physical properties. It is a solid, usually in the form of white to light yellow powder. This color and shape are crucial for observation and identification. The melting point is between 73 and 77 ° C. Under certain temperature conditions, the state of matter will change from solid to liquid. This melting point characteristic has a profound impact on its existence and application in different temperature environments.
    Furthermore, 3 - Bromoisothiazole is insoluble in water. This solubility characteristic determines its dispersion and reaction in water systems. It interacts weakly with water and is difficult to form a uniform dispersion system in water. However, it is soluble in some organic solvents, such as common chloroform, dichloromethane, etc. In these organic solvents, it can be well dissolved, which in turn facilitates its application in organic synthesis and other fields. Because organic solvents are often used as reaction media to help them participate in various chemical reactions.
    In addition, 3-Bromoisothiazole has a certain degree of volatility. Although the volatility is not strong, under certain environmental conditions, such as temperature rise and good ventilation, its molecules will gradually evaporate from the solid surface into the surrounding air. And its smell is weak. Under normal circumstances, the smell is not pungent and strong, and it needs to be smelled closely before it can be detected. These physical properties, taken together, play a crucial role in the storage, transportation, and use of 3-Bromoisothiazole in chemical production, scientific research experiments, and many other scenarios. Practitioners must be familiar with and properly use these properties to ensure the safe and efficient operation of related operations.
    What are the main uses of bromoisothiazole?
    3-Bromoisothiazole is one of the organic compounds. It has a wide range of uses and is widely used in the field of medicine and chemical industry.
    In the process of pharmaceutical creation, it can be used as a key intermediate. Due to its unique structure, it can undergo specific chemical reactions with many substances and assist in the synthesis of compounds with special pharmacological activities. Or it can be used to develop antibacterial drugs. Through its unique chemical properties, it can act on specific targets of bacteria and interfere with the normal physiological activities of bacteria to achieve antibacterial effect. Or it can contribute to the development of anti-tumor drugs, which are chemically modified to connect with other structural units to construct new anti-tumor active molecules, contributing to the solution of cancer problems.
    In the field of chemical engineering, in the field of materials science, 3-bromoisothiazole can also play an important role. For example, it can participate in the synthesis of special polymer materials. After ingeniously designing chemical reactions, it is introduced into the polymer chain segment to give the material special properties such as antibacterial and weathering resistance. In this way, the material may be applied to food packaging with strict hygiene requirements, or to long-term outdoor use of building materials that need to resist environmental erosion.
    Furthermore, at the level of pesticide research and development, it can be used as a basic structure for building high-efficiency and low-toxicity pesticide molecules. By combining with other active groups, a new type of pesticide with high selectivity to pests and environmental friendliness can be created, which can not only effectively kill pests, ensure a good harvest of crops, but also reduce the harm to the ecological environment.
    In short, 3-bromoisothiazoline has its own special chemical structure, which is indispensable in many fields such as medicine and chemical industry, and has made great contributions to promoting technological progress and innovative development in various fields.
    What are the synthesis methods of 3-Bromoisothiazole?
    The synthesis method of 3-bromo isothiazole has always been an ancient method. First, it starts with specific sulfur-containing and nitrogen-containing compounds, and through condensation reaction, it forms the basic structure of isothiazole. In a suitable solvent, thiols and nitriles are slowly reacted under the catalysis of bases. This process requires precise temperature control. Depending on the characteristics of the reactants, the temperature is usually between room temperature and tens of degrees Celsius. The reaction lasts for several hours or even days to achieve the expected condensation effect.
    Furthermore, after obtaining the isothiazole parent, bromine atoms are to be introduced. The bromination reaction can be carried out under suitable reaction conditions with bromine or other brominating reagents, such as N-bromosuccinimide (NBS). If bromine is used, it is often diluted with an inert solvent such as dichloromethane. Under low temperature or light assistance, bromine is slowly added dropwise to selectively replace hydrogen atoms at specific positions of isothiazole to obtain 3-bromoisothiazole. If NBS is used as the brominating agent, the reaction conditions are relatively mild. In the presence of an initiator such as an organic peroxide, the reaction in a suitable solvent can also achieve the formation of the target product. All kinds of synthesis methods require careful regulation of the reaction conditions, from the proportion of raw materials, temperature, reaction time to solvent selection, all of which are related to the purity and yield of the product. The operator must carefully review it before it can be achieved.
    3-Bromoisothiazole What are the precautions in storage and transportation?
    3-Bromoisothiazole is also an organic compound. During storage and transportation, many matters must be paid attention to.
    First word storage. This substance should be stored in a cool and ventilated warehouse. Because of the cool and ventilated place, it can reduce the danger caused by excessive temperature or lack of air circulation. The temperature of the warehouse should be strictly controlled and not too high to prevent its chemical properties from changing. And it must be kept away from fire and heat sources, both of which can cause fire or explosion. Because of its certain chemical activity, it should be stored separately from oxidizing agents, acids, bases, etc., and must not be mixed. Due to its chemical properties, it encounters with their substances, or reacts biochemically, causing them to deteriorate, or even causing dangerous accidents. Storage places must also be equipped with suitable materials to contain leaks, so as to prevent accidental leakage, which can be handled in time to prevent its spread and cause greater harm.
    As for transportation. Before transportation, make sure that the packaging is complete and sealed. If the packaging is damaged, the substance or leakage will not only damage the goods, but also endanger the safety of transportation. During transportation, the speed of the vehicle should be stable, and violent actions such as sudden braking and sharp turning should be avoided to prevent packaging collision damage. Transportation vehicles must also be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. If there is an accident such as leakage on the way, it can be dealt with in time. And when transporting, you should follow the prescribed route and do not stop in densely populated areas or residential areas to reduce the harm to the public in the event of an accident.