Chemical Name | 3,4 - dichloro - N - (2 - cyanophenyl)-1,2 - thiazole - 5 - carboxamide |
Molecular Formula | C10H5Cl2N3OS |
Molecular Weight | 286.138 g/mol |
Appearance | Typically a solid (appearance may vary based on purity and preparation) |
Melting Point | Data may vary depending on purity; needs experimental determination |
Boiling Point | Data may vary depending on purity; needs experimental determination |
Solubility | Solubility characteristics depend on solvents, e.g., may have low solubility in water, solubility in some organic solvents |
Pka | Data may vary depending on experimental conditions; needs experimental determination |
Logp | Data may vary depending on experimental methods; needs experimental determination |
Stability | Stability can be affected by factors like temperature, light, and humidity |
What are the chemical properties of 3,4-dichloro-N- (2-cyanophenyl) -1,2-thiazole-5-formamide?
3% 2C4-difluoro-N- (2-fluorophenyl) - 1% 2C2-benzisoxazole-5-acetamide is an organic compound. This compound has unique chemical properties due to its specific molecular structure.
From its structural point of view, the introduction of fluorine atoms significantly affects its properties. Fluorine atoms have high electronegativity, which can enhance molecular polarity and have a significant impact on the solubility, stability and biological activity of compounds. In organic solvents, their solubility or the presence of fluorine atoms is different from fluorine-free analogs.
Furthermore, the benzisoxazole ring endows this compound with certain rigidity and conjugation system. The conjugated system often affects the electron cloud distribution of the compound, which in turn affects its optical and electrical properties. This structure may enable the compound to exhibit a special electronic transition behavior under light.
The presence of acetamide groups adds hydrogen bond donors and receptors to the molecule. This allows the compound to interact with other molecules through hydrogen bonds, which affects its aggregation state in solution and its ability to bind to biomacromolecules.
In terms of chemical reactivity, the compound can participate in a variety of reactions due to the presence of different functional groups. For example, the electrophilic substitution reaction can be carried out on the benzene ring, which is affected by the positioning effect of fluorine atoms and other groups, and the reaction check point is selective. The carbonyl group of acetamide can participate in reactions such as nucleophilic addition, showing rich chemical transformation pathways.
Overall, 3% 2C4-difluoro-N - (2-fluorophenyl) - 1% 2C2-benzisoxazole-5-acetamide integrates a variety of chemical properties due to its unique molecular structure, and may have potential application value in organic synthesis, medicinal chemistry and other fields.
What are the uses of 3,4-dichloro-N- (2-cyanophenyl) -1,2-thiazole-5-formamide?
3% 2C4 - difluoro - N- (2 - fluorophenyl) - 1% 2C2 - phenylenediamine - 5 - methylpyridine, this is a fine chemical substance. It is widely used in the field of medicine and can be used as a key intermediate in drug synthesis. With its specific chemical structure, it can participate in the construction of many drug molecules, which is of great significance for the development of new drugs, or can be used for the creation of antibacterial, antiviral and other drugs. By combining with specific targets of pathogens, it interferes with their physiological processes and exerts therapeutic effects.
In the field of materials science, it also has good performance. It can be chemically modified and integrated into the polymer material system to give the material unique properties, such as enhancing the corrosion resistance of the material and improving its optical properties. For example, adding this substance to the preparation of some high-performance coatings may improve the coating's anti-aging and chemical resistance, and prolong the service life of the material.
In the field of pesticide research and development, it is also indispensable. Or it can become a new type of pesticide active ingredient. With its biological activity against specific pests or pathogens, it can precisely attack pests, help agricultural production, and is relatively friendly to the environment, reducing many negative effects caused by traditional pesticides.
In the study of organic synthetic chemistry, it is like a "key", opening up new paths for the construction of complex organic molecular structures. Scientists use their unique functional groups to achieve the synthesis of various novel organic compounds through ingenious reaction design, promoting the development of cutting-edge research in organic chemistry.
What is the synthesis method of 3,4-dichloro-N- (2-cyanophenyl) -1,2-thiazole-5-formamide?
To prepare 3% 2C4-difluoro-N- (2-fluorophenyl) -1,2-benzisoxazole-5-acetamide, the method is as follows:
Take an appropriate amount of 2-fluoroaniline first, and shield its amino group with an appropriate protective group, which can prevent its gratuitous participation in the subsequent reaction and cause the reaction to be disordered. After the group is blocked, it is treated with an electrophilic fluorination reagent to introduce fluorine atoms at specific positions in the phenyl ring to obtain fluorine-containing aniline derivatives. < Br >
Then the derivative is co-heated with an appropriate acylation reagent. The choice of acylation reagent needs to meet the reaction conditions and product structure requirements, so that the amino group is connected to the acyl group to form an amide structure. When the amide is formed, carefully remove the previous protective group to restore the activity of the amino group.
Then, a specific cyclization reagent is used to make the inner ring of the molecule to construct the ring system of 1,2-benzisoxazole. During cyclization, the reaction conditions must be precisely controlled, such as temperature, solvent, catalyst dosage, etc., all affect the efficiency and selectivity of cyclization.
Finally, the obtained cyclization product is reacted with the ethylation reagent under suitable conditions, and the acetyl group is introduced at the 5-position to obtain the target product 3% 2C4-difluoro-N- (2-fluorophenyl) -1,2-benzisoxazole-5-acetamide. After each step of the reaction, it needs to be separated and purified, such as column chromatography, recrystallization, etc., to maintain the purity of the product, and then achieve the purpose of synthesis.
What is the market price of 3,4-dichloro-N- (2-cyanophenyl) -1,2-thiazole-5-formamide?
I don't know what you mean by "3%2C4-%E4%BA%8C%E6%B0%AF-N-%282-%E6%B0%B0%E5%9F%BA%E8%8B%AF%E5%9F%BA%29-1%2C2-%E5%99%BB%E5%94%91-5-%E7%94%B2%E9%85%B0%E8%83%BA". The name is very strange, and it seems to be an extremely rare or newly created chemical.
It is difficult to know its market price. Because I don't know the key factors such as the use of this thing, the difficulty of making it, and the market supply and demand. If it is commonly available and not widely used, the price may be low; if it is difficult to make, the use is special, and the demand is large, the price must be high.
There is no more information to be found, so it is difficult to determine its exact price. More detailed information on the characteristics, uses, and market circulation of this thing is needed to briefly measure its price. If there is any information on where this item is produced, where it is mainly used, and the amount of output, etc., or its price range can be pushed, it is difficult to determine based on this name alone.
What are the manufacturers of 3,4-dichloro-N- (2-cyanophenyl) -1,2-thiazole-5-formamide?
I look at what you said about "3% 2C4-dioxy-N- (2-hydroxyphenyl) -1,2-pyrrole-5-acetic acid", which is a rather professional chemical substance. However, it is not easy to know its manufacturer.
In the chemical field of today, many manufacturers have their product areas of focus. The production of these fine chemicals requires specific technologies, equipment and qualifications. There may be large chemical companies with strong R & D and capacity, or involved in the manufacture of such products. However, they also need to follow strict regulations and standards to ensure product quality and safety.
Or there may be small manufacturers specializing in fine chemicals. Although they are slightly smaller in scale, they have deep research in specific fields, and may also be manufacturers of this substance. To know for sure, you need to check the chemical industry directory, relevant industry reports, or consult experts and practitioners in the chemical field. They may be able to inform you of possible manufacturers based on their practical experience and knowledge. However, this matter is complicated and needs to be explored by many parties to obtain more accurate information.