2 Thiazolecarboximidamide Hydrochloride
quinoline thiophene imidazole thiazole

2-Thiazolecarboximidamide hydrochloride

    Specifications

    HS Code

    469729

    Chemical Formula C4H6ClN3S
    Molecular Weight 163.63 g/mol
    Appearance Solid
    Color White to off - white
    Odor May have a characteristic odor
    Solubility In Water Soluble
    Melting Point Typically in a certain temperature range (exact value depends on purity)
    Ph In Solution Acidic due to hydrochloride salt
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

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    2-Thiazolecarboximidamide chemical structure of hydrochloride
    The chemical structure of 2-thiazole formamidine hydrochloride is quite exquisite. Thiazole is a five-membered heterocyclic ring containing sulfur and nitrogen. In the structure of 2-thiazole formamidine hydrochloride, the thiazole ring is the base. At the 2-position on the ring, formamidine is connected, and formamidine is in the shape of -C (= NH) NH 2, in which carbon and nitrogen are connected by double bonds, and are connected with diamino groups. For hydrochloride, the reaction of the Gai molecule with hydrochloric acid results in a salt of cations and chloride ions. In this structure, the electronic properties of the heterocyclic ring interact with the reactivity of formamidine, causing it to exhibit unique properties in the fields of organic synthesis and medicinal chemistry, such as the ability to interact with specific receptors by hydrogen bonds, electrostatic forces, or the conjugation effect of the ring and functional groups, which affects its reaction pathways and products. This is one of the interesting examples in the structure of organic compounds.
    What are the main uses of 2-Thiazolecarboximidamide hydrochloride?
    2-Thiazolformamidine hydrochloride, an important chemical substance, has a wide range of uses. In the field of medicine, it is often a key intermediate for the synthesis of many drugs. The preparation of many antibacterial and antiviral drugs depends on its participation. Gainthiazole compounds have unique structures, which endow them with potential biological activities. After rational modification and synthesis, drugs with specific pharmacological activities can be prepared.
    In the field of pesticides, 2-thiazolformamidine hydrochloride is also used. It can be used as a raw material for the synthesis of new pesticides, used to prepare insecticides, fungicides, etc. Due to its structural characteristics, it may be able to inhibit or kill specific pests and pathogens, assisting in the control of agricultural pests and diseases, and ensuring the growth and yield of crops.
    Furthermore, in the field of organic synthesis, it is an important class of reaction substrates. With the activity of amidine groups and thiazole rings, it can participate in a variety of organic reactions, such as reacting with various nucleophiles and electrophiles, to construct more complex organic molecular structures, providing an important basic raw material for the development of organic synthesis chemistry. In short, 2-thiazolamidine hydrochloride plays an indispensable role in many fields such as medicine, pesticides and organic synthesis.
    What are the physical properties of 2-Thiazolecarboximidamide hydrochloride?
    2-Thiazolformamidine hydrochloride, this material property is special, and it is related to various fields of chemical medicine. Its color state is often white or white-like crystalline powder, which is fine in appearance and uniform in texture. In terms of solubility, it is easily soluble in water, just like salt melts in water, quietly disappearing invisible, this property makes it easy to react and operate in aqueous solution systems. Its melting point is specific, about a certain range, which is a sign of authenticity and purity. If the temperature does not reach this point, it is difficult to dissolve the form. And it has a certain stability. In case of strong acid and alkali, it is still beautiful and beautiful in the rain, with structure or change, causing performance migration. In organic solvents, the solubility is different. It is slightly soluble in alcohols and slightly soluble in ethers. This property is crucial for separation and purification steps. Due to its unique physical properties, it is often a key intermediate in the organic synthesis path, affecting the success or failure of the product. In the field of medicine, it also develops its capabilities to contribute to the creation of new agents, leveraging its physical properties to fit with biomolecules and achieve therapeutic effects.
    What is the synthesis method of 2-Thiazolecarboximidamide hydrochloride?
    The synthesis of 2-thiazole formamidine hydrochloride is particularly important, and it is related to the preparation of this chemical. In order to synthesize, it is first necessary to select suitable starting materials. It is often based on thiazole compounds, because its structure is related to the target product.
    In the past, most of the thiazole derivatives were selected through a series of chemical reactions to achieve the purpose of synthesis. First, the thiazole derivative is reacted with a nitrogen-containing reagent. This step is the key to introducing the amidine group. Or cyanamide compounds are combined with thiazole derivatives under suitable reaction conditions. During the reaction, factors such as temperature and solvent need to be carefully controlled. Usually an organic solvent is used as the reaction medium, such as ethanol, dichloromethane, etc., to facilitate the reaction. The temperature varies depending on the reaction characteristics, either at room temperature or heated to a moderate temperature, such as 50-80 degrees Celsius, to promote the full reaction.
    After the reaction is completed, a mixture containing the target product is obtained. Subsequent separation and purification steps are required to obtain a pure 2-thiazolformamidine hydrochloride. Often by recrystallization, a suitable solvent is selected to dissolve the product, and then cooled and crystallized to precipitate pure crystals. Or column chromatography is used to separate the product and impurities in the stationary phase and the mobile phase. In this way, the synthesis of 2-thiazolformamidine hydrochloride can be achieved through the steps of raw material selection, reaction operation, separation and purification, etc.
    What are the precautions for the use of 2-Thiazolecarboximidamide hydrochloride?
    2-Thiazolformamidine hydrochloride is a chemical substance. During use, there are several precautions that need to be paid attention to.
    First, safety protection must not be taken lightly. This substance may be toxic and irritating. When exposed, be sure to wear appropriate protective equipment. Wear protective gloves to prevent direct contact with the skin, causing skin allergies, burns, etc.; wear goggles to protect the eyes from damage. If accidentally splashed into the eyes, rinse with plenty of water immediately and seek medical attention in time.
    Second, storage conditions are also crucial. Store it in a dry, cool and well-ventilated place, away from fire and heat sources. Because of its chemical properties or cause reactions in improper environments, affect quality, or even cause safety accidents. And it needs to be stored separately from oxidants, acids, etc., to avoid interaction.
    Third, the use operation must be rigorous. When taking it, it needs to be carried out according to the exact dosage, and the weighing process should be accurate to prevent the dosage deviation from affecting the experiment or production results. The use environment needs to have good ventilation facilities to prevent its volatile gases from accumulating in the air and endangering human health.
    Fourth, waste disposal should not be arbitrary. After use, the remaining substances and related waste should be treated in accordance with specific regulations, and must not be discarded at will to prevent pollution to the environment. Appropriate methods must be selected for disposal according to local environmental protection requirements. Only in this way can the use of 2-thiazolformamidine hydrochloride ensure safety, effectiveness and avoid adverse consequences.