2-[(tert-butylamino)sulfanyl]-1,3-benzothiazole

2-% 5B% 28tert - butylamino%29sulfanyl%5D - 1% 2C3 - benzothiazole, the Chinese name may be called 2- [ (tert-butylamino) thio] -1,3 - benzothiazole. This substance has a wide application field and can be used as a key intermediate in the field of medicinal chemistry to help create new drugs. The structure of Gainbenzothiazole has a variety of biological activities and can interact with many targets in organisms. For example, in the development of antibacterial drugs, compounds with inhibitory activity against specific pathogens can be designed by virtue of their structural properties; in the exploration of anticancer drugs, novel anticancer agents may be developed based on their potential to bind to cancer cell targets. < Br >
In the field of materials science, it also has a place of use. It can participate in the synthesis of functional materials, for example in optical materials, or because of its special molecular structure, it endows materials with unique optical properties, such as fluorescence properties, and can be used to prepare fluorescence sensors for highly sensitive detection of specific substances; in the field of electrical materials, it may affect the electrical conductivity of materials, providing the possibility for the development of new conductive materials.
In the field of agricultural chemistry, it can be used as an important starting material for the creation of pesticides. Due to its structure may have biological activities such as insecticidal, bactericidal or weeding, after reasonable structural modification and optimization, it is expected to develop high-efficiency, low-toxicity and environmentally friendly new pesticides, which can help agricultural pest control and weed control, and ensure crop yield and quality.

To prepare 2 - [ (tert-butylamino) thio] -1,3 -benzothiazole, there are various methods.
First, o-aminothiophenol can be used with carbon disulfide and tert-butylamine as raw materials. First, the o-aminothiophenol and carbon disulfide are reacted under appropriate conditions to form an intermediate product. This step requires temperature control and reaction time. Too high or too low temperature affects the yield. After adding tert-butylamine, it is converted into the target product through a series of reactions. Pay attention to the choice of solvent during the reaction process. Organic solvents such as ethanol and toluene have an impact on the reaction process. < Br >
Second, use 2-chloro-1,3-benzothiazole and sodium tert-butyl mercaptan as starting materials. Dissolve 2-chloro-1,3-benzothiazole in a suitable solvent, such as N, N-dimethylformamide, and slowly add sodium tert-butyl mercaptan under stirring. This reaction needs to be carried out under the protection of inert gas to avoid oxidation of the reactants. At the same time, the pH of the reaction also needs to be adjusted. A weak base such as potassium carbonate can be used to maintain a suitable alkaline environment to promote the smooth progress of the reaction.
Third, o-nitrothiophenol can also be used as the starting material. First reduce o-nitrothiophenol to o-aminophenol, commonly used reducing agents such as iron powder, zinc powder, etc. After obtaining o-aminophenol, then react with carbon disulfide and tert-butylamine according to the above first step, and finally obtain 2- [ (tert-butylamino) thio] -1,3 -benzothiazole. Each method has its own advantages and disadvantages, and it needs to be carried out according to actual needs, such as the availability of raw materials, cost and yield.

2-% 5B% 28tert - butylamino%29sulfanyl%5D - 1,3 - benzothiazole, this is an organic compound. Its physical and chemical properties are unique and significant in many fields of chemistry.
Looking at its physical properties, under normal conditions, it may be a solid, because it contains complex aromatic rings and specific substituents, and the intermolecular forces are relatively strong. As for the melting boiling point, the intermolecular forces caused by aromatic rings and substituents are enhanced, so the melting boiling point may be higher. In terms of solubility, its structure contains lipophilic aromatic rings and tert-butyl groups, which are poorly hydrophilic and have very low solubility in water; however, in organic solvents such as ethanol and dichloromethane, due to the principle of similar miscibility, it may have a certain solubility.
In terms of its chemical properties, among the compounds, the 1,3-benzothiazole ring system is aromatic, relatively stable, and can undergo electrophilic substitution reactions, such as halogenation, nitrification, etc. The reaction check point is mostly in the higher electron cloud density of the benzene ring. And the sulfur atom of the thiazole ring has a lone pair of electrons, which can be used as an electron donor to participate in coordination chemistry-related reactions. Furthermore, the sulfur atom connected to nitrogen, whose C-S bond and S-N bond may have certain reactivity, can participate in nucleophilic substitution or elimination reactions, and is affected by the reagents and reaction conditions. For example, when encountering nucleophilic reagents, or under appropriate conditions, the groups attached to the sulfur atom are replaced. In addition, the nitrogen atom of the tert-butyl amino group has a lone pair of electrons, is basic, and can react with acids to form salts or participate in nucleophilic reactions.

Today I have a question, what is the price of 2 - [ (tert-butylamino) thio] -1,3 -benzothiazole in the market? This is a compound in the field of fine chemicals. The range of price is subject to various factors.
First, the price of raw materials has a huge impact. If the starting material for the synthesis of this compound changes in its origin and output, or due to supply and demand imbalance, natural disasters and man-made disasters, the price of the finished product will also fluctuate. If the raw material is scarce and the price is high, the price of this compound will rise; otherwise, it will fall.
Second, the preparation process is very simple. If its synthesis requires delicate steps and harsh conditions, such as specific catalysts, high temperature and high pressure, etc., the production cost will increase greatly and the price will be high. On the contrary, the process is simple, the cost will be reduced and the price will be low.
Furthermore, the market supply and demand trend affects its price. If an industry has a strong demand for this compound, such as pharmaceuticals, materials science and other fields, there is a large demand for it, but the supply is limited, and the price will rise; if the market is saturated, the supply will exceed the demand, and the price will fall.
Also, the quality specification is related to the price. High purity, specific crystal forms or those that meet special standards are often higher than ordinary products.
In summary, the market price of 2- [ (tert-butylamino) thio] -1,3-benzothiazole ranges from a few to several hundred yuan per gram. The simplest, slightly lower purity, easy to prepare, gram price or only a few hundred yuan; while high purity, special specifications and difficult to prepare, gram price can reach several hundred yuan. This is only a rough estimate, the actual price needs to be considered in detail the current market situation.

2-% 5B% 28tert - butylamino%29sulfanyl%5D - 1% 2C3 - benzothiazole, this substance is an organic compound, occasionally involved in chemical synthesis and other fields. However, its safety and toxicity are of paramount importance, and it is related to human health and environmental safety.
Although it is not directly described in the ancient book "Tiangong Kaiwu", it can be inferred by analogy based on the methods of ancient people's exploration of physical properties. In terms of safety, the structure of this substance contains heteroatomic groups such as sulfur and nitrogen, or has certain chemical activity. If it accidentally touches the skin, or causes skin irritation, it is like being contaminated with spicy substances, making the skin uncomfortable. If it inhales dust or volatile gases by mistake, or affects the respiratory tract, it seems to inhale smoke and dust, making the airway unsmooth.
When it comes to toxicity, the sulfur-nitrogen structure or metabolism in the body produces harmful intermediates. If eaten by mistake, or interferes with the normal biochemical reactions of the human body, it is like foreign matter entering the body and messing with the organs. Toxic to the environment, if it flows into natural water bodies, or is harmful to aquatic organisms, just like poison entering the water, endangering aquatic life.
Although no ancient people have made a definite conclusion on it, it is deduced from chemical principles and similar structural substances. 2-% 5B% 28tert - butylamino%29sulfanyl%5D - 1% 2C3 - benzothiazole should be treated with caution. Take good protection during operation to prevent it from causing damage to people and the environment.