What is the chemical structure of 2- ((tert-butoxycarbonyl) amino) -4,5,6,7-tetrahydrobenzo [d] thiazole-6-carboxylic acid?

The chemical structure of 2 - (tert - butoxycarbonyl) amino) -4, 5, 6, 7 - tetrahydrobenzo [d] thiazole - 6 - carboxylic acid, and listen to me in detail.

In the structure of this compound, the core is the benzothiazole ring, and the benzene ring part is fused with the thiazole ring. The modification of 4,5,6,7 - tetrahydro, the benzene ring part of the epibenzothiazole ring, is hydrogenated at the 4,5,6,7 position, that is, has a saturated carbon-carbon single bond.

At the 2nd position, there are ((tert - butoxycarbonyl) amino) groups. In this group, tert-butoxycarbonyl (tert-butoxycarbonyl) is a common protective group. In its structure, the carbonyl group (C = O) is connected to the tert-butoxycarbonyl group (-OC (CH 🥰) 🥰), and the other side of the carbonyl group is connected to the amino group (-NH -), and then to the carbon at the 2nd position of the benzothiazole ring.

at the 6th position, with a carboxyl group (-COOH), which is a typical acidic functional group.

Thus, the chemical structure of 2 - ((tert - butoxycarbonyl) amino) -4, 5, 6, 7 - tetrahydrobenzo [d] thiazole - 6 - carboxylic acid consists of a specific hydrogenated benzothiazole ring as the core, with characteristic functional groups at the 2nd and 6th positions, respectively, forming its unique chemical structure.

2- ((tert-butoxycarbonyl) amino) -4,5,6,7-tetrahydrobenzo [d] thiazole-6-carboxylic acid What are the common synthesis methods?

2-% 28% 28tert - butoxycarbonyl%29amino%29 - 4% 2C5% 2C6% 2C7 - tetrahydrobenzo%5Bd%5Dthiazole - 6 - carboxylic acid, that is, 2 - ((tert-butoxycarbonyl) amino) - 4,5,6,7 - tetrahydrobenzo [d] thiazole-6 - carboxylic acid. Common synthesis methods are as follows:

The starting material is often selected from benzothiazole derivatives containing suitable substituents. One method is to first react a compound containing nitrogen and sulfur atoms with a suitable halogen to construct a thiazole ring structure. The obtained intermediate is then protected by the method of protecting the amino group with tert-butoxycarbonyl (Boc). This protection method mostly uses Boc anhydride as a reagent, and reacts in the presence of suitable bases, such as triethylamine, etc., to protect the amino group by the Boc group.

Then, where the carboxyl group needs to be introduced into the p-benzothiazole ring, the carboxyl group can be introduced through a suitable reaction strategy. Functional groups that can be converted into carboxyl groups, such as halogen atoms, can be introduced first, and then metal reagents, such as Grignard reagents, react with carbon dioxide to convert halogen atoms into carboxyl groups. The reaction conditions need to be anhydrous and oxygen-free, and the reaction temperature, time and other parameters are strictly controlled, so that the reaction can proceed smoothly, and the target product 2 - ((tert-butoxycarbonyl) amino) -4,5,6,7 -tetrahydrobenzo [d] thiazole-6 -carboxylic acid can be obtained.

There is also another method, using a suitable amino acid derivative as the starting material, cyclizing to construct a thiazole ring, and then performing amino protection and carboxyl group introduction steps. The principle is similar to the previous method, and the reaction conditions need to be carefully adjusted according to the characteristics of each step of the reaction.

What are the physical properties of 2- ((tert-butoxycarbonyl) amino) -4,5,6,7-tetrahydrobenzo [d] thiazole-6-carboxylic acid?

2 - (tert - butoxycarbonyl) amino) -4, 5, 6, 7 - tetrahydrobenzo [d] thiazole - 6 - carboxylic acid is an organic compound, and its physical properties are worth exploring. The appearance of this compound may be white to off-white solid, because of the arrangement and interaction of atoms in its molecular structure, it appears in this form at room temperature and pressure.

Its melting point is also an important physical property. Due to the existence of specific forces between molecules, such as hydrogen bonds, van der Waals forces, etc., it is given a certain melting point range. However, in order to accurately determine, it is necessary to use experimental means and instruments such as melting point meters to accurately measure.

In terms of solubility, it may exhibit certain solubility in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF). Because the molecular structure of the compound contains specific functional groups, hydrogen bonds, dipole-dipole interactions, etc. can be formed with organic solvent molecules, which in turn affects its solubility. In water, because of the existence of the hydrophobic part of the molecular structure, the solubility may be limited.

In addition, the density of the compound is also affected by the molecular structure and constituent atoms. Although there is no exact value, it can be estimated theoretically based on its molecular weight and molecular stacking mode.

Because of the conjugated system and specific functional groups in the molecule, there will be characteristic absorption peaks or signals in the spectroscopic characterization of infrared spectroscopy, nuclear magnetic resonance spectroscopy, etc., which is helpful for the accurate analysis and confirmation of its structure.

The above physical properties are based on the general understanding of the relationship between the structure and properties of organic compounds, and the actual values still need to be accurately determined experimentally.

2- ((tert-butoxycarbonyl) amino) -4, 5, 6, 7-tetrahydrobenzo [d] thiazole-6-carboxylic acid in which applications?

2-% 28% 28tert - butoxycarbonyl%29amino%29 - 4% 2C5% 2C6% 2C7 - tetrahydrobenzo%5Bd%5Dthiazole - 6 - carboxylic acid, that is, 2 - ((tert-butoxycarbonyl) amino) - 4,5,6,7 - tetrahydrobenzo [d] thiazole - 6 - carboxylic acid, which is used in medicine and organic synthesis.

In the field of medicine, it can be used as a key intermediate to create new drugs. Due to its unique chemical structure, it contains active groups such as thiazole ring and carboxyl group, which can interact with specific targets in organisms and participate in the regulation of physiological and biochemical processes. For example, in the development of antibacterial drugs, the compound can be used to construct a molecular structure with antibacterial activity, which can inhibit the growth and reproduction of bacteria by binding to key enzymes or proteins in bacteria, and achieve antibacterial effect. Or in the research of anti-cancer drugs, by modifying the structure of the compound, it can precisely act on specific targets of cancer cells, interfere with cancer cell proliferation, apoptosis and other signaling pathways, and then exert anti-cancer activity.

In the field of organic synthesis, as an important synthetic building block, it can participate in various organic reactions and construct complex organic molecular structures. For example, carboxyl groups can undergo esterification reactions, react with alcohols under specific conditions to form ester compounds, and expand the structural diversity of compounds. The tert-butoxycarbonyl (Boc) on the amino group acts as a protective group, which can effectively protect the amino group in the organic synthesis sequence, preventing it from participating in the reaction at the stage where the reaction is not required. When the time is appropriate, the protective group is removed, and the amino group is allowed to participate in the subsequent reaction, so as to achieve the precise synthesis of complex organic molecules. It provides an effective way for the synthesis of organic materials with specific functions and structures, and the total synthesis of natural products.

2- ((tert-butoxycarbonyl) amino) -4,5,6,7-tetrahydrobenzo [d] What is the market outlook for thiazole-6-carboxylic acid?

2-% 28% 28tert - butoxycarbonyl%29amino%29 - 4% 2C5% 2C6% 2C7 - tetrahydrobenzo%5Bd%5Dthiazole - 6 - carboxylic acid, that is 2- ((tert-butoxycarbonyl) amino) -4,5,6,7-tetrahydrobenzo [d] thiazole-6-carboxylic acid, this compound has great potential in the field of medicine and chemical industry. Its market prospects are as follows.

Looking at the current market, this compound has emerged on the path of drug development. In the process of innovative drug exploration, its structural characteristics endow unique pharmacological activity, which may open up new avenues for the treatment of specific diseases. Taking the research and development of anti-cancer drugs as an example, studies have found that its structure can interact with specific targets of cancer cells and inhibit the proliferation of cancer cells, just like a precise arrow, directly attacking the source of the disease, so there is a broad space for expansion in the anti-cancer drug research and development market.

Furthermore, in the field of chemical synthesis, as a key intermediate, it can participate in the synthesis of a series of high-value-added compounds. For example, the preparation of fine chemicals, with its unique structure, can derive a variety of functional materials, which seem to be the cornerstone of the chemical industry, supporting the birth of many high-end products, and prompting the increasing demand for chemical raw materials in the market.

However, its market development is not smooth sailing and faces challenges. On the one hand, the synthesis process is complex and the cost remains high, which is just like a boulder moving forward, hindering large-scale production and On the other hand, the market competition is fierce, and similar compounds continue to emerge. If you want to stand out in the market, you need to accelerate the research and development process and improve product quality and performance.

Despite the challenges, the future of 2- ((tert-butoxycarbonyl) amino) -4,5,6,7-tetrahydrobenzo [d] thiazole-6-carboxylic acid remains bright. With the development and research of science and technology, the synthesis process may be optimized, the cost is reduced, and its potential value in the pharmaceutical and chemical fields will surely achieve great results in the future market, injecting new vitality into the development of the industry.