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What is the chemical structure of 2-Sulfanilamidothiazole?
2-Sulfathiazole, its chemical structure is quite delicate and complex. Looking at this compound, the core is a thiazole ring, which is composed of a sulfur atom and a nitrogen atom to form a five-membered shape, which seems to have a stable state. At the 2-position of the thiazole ring, there is a sulfadiazole group connected. The structure of the sulfadiazole group is based on a sulfonyl group. The sulfur atom in the sulfadiazole group is connected to two oxygen atoms in a double bond, and the sulfur atom is connected to an amino group. The hydrogen atom on this amino group can be changed by reaction and has a certain activity.
From the perspective of the overall structure, sulfathiazole fuses the properties of the thiazole ring with the properties of the sulfadiazole group. The existence of the thiazole ring endows it with a specific spatial configuration and electron cloud distribution, which affect the physical and chemical properties of the molecule. The sulfonyl group brings biological activities such as antibacterial. Because of its structure, the amino and sulfonyl groups of the sulfonyl group can interact with enzymes or metabolites required for bacterial growth, interfering with the normal physiological process of bacteria and achieving antibacterial effects. The delicate design of this chemical structure makes 2-sulfonamthiazole unique in the field of medicine.
What are the main uses of 2-Sulfanilamidothiazole?
2-Sulfamethiazole has a wide range of functions. In the field of medicine, this is a key antibacterial drug. It can be used to deal with infections caused by many bacteria, such as pneumonia, otitis media, tonsillitis and other diseases caused by pneumococcus and hemolytic streptococcus. Its antibacterial principle is to inhibit the synthesis of bacterial folic acid, which in turn hinders the growth and reproduction of bacteria.
In agriculture, 2-sulfamethiazole also has its uses. It can be used as a fungicide to inhibit the pathogens of some crops, and can help crops resist diseases and improve yield and quality. For example, for the infection of common pathogens in some fruits and vegetables, timely application of this drug can reduce the spread of diseases and protect the healthy growth of fruits and vegetables.
Furthermore, in specific aspects of industrial production, 2-sulfamethiazole can be used as a specific additive due to its special chemical properties. In the manufacturing process of some chemical products, adding an appropriate amount of this substance may improve the performance of the product, such as enhancing the stability of the product, etc. However, this application is slightly niche than medicine and agriculture. In short, 2-sulfamethiazole has important uses in medicine, agriculture and some industrial fields, contributing to the development of various industries.
What are the side effects of 2-Sulfanilamidothiazole?
2-Sulfamethiazole, although it is a medicinal agent, is also at risk of various side effects. Its side effects on the body are first related to allergies. People with allergies use it, or see drug rashes, itching, and even can cause exfoliative dermatitis, bullosa epidermolysis atrophic dermatitis and other serious diseases, endangering life.
The second is related to the hematopoietic system. It can cause leukopenia, even lack of granulocytes, the body's ability to control disease is greatly reduced, and it is prone to various infections; it can also cause thrombocytopenia, impaired coagulation, and the risk of bleeding, such as skin petechiae, petechiae, or even visceral bleeding.
Furthermore, it also affects the urinary system. In acidic urine, this drug is easy to crystallize and block the urinary tract, causing urinary pain, hematuria, and urinary closure.
In addition, it can cause gastrointestinal discomfort. Common symptoms of nausea, vomiting, and loss of appetite, long-term use may cause damage to gastrointestinal mucosa, leading to ulcers and bleeding.
The nervous system may also be affected by it. Occasionally headache, dizziness, and fatigue occur, and a few people may experience psychiatric symptoms such as depression, hallucinations, etc.
When using 2-sulfamethiazole, the doctor should carefully review the situation and weigh the pros and cons. The patient also needs to follow the doctor's advice to strictly observe the changes in the body. If there is any abnormality, seek medical treatment quickly to prevent side effects.
What is 2-Sulfanilamidothiazole production method?
2-Sulfamethiazole, an ancient method of pharmacy, is delicate and complicated. Although the years have passed, its ancient method is also considerable.
To make 2-sulfamethiazole, first take appropriate raw materials. Based on p-aminobenzenesulfonamide and 2-chlorothiazole, these two are the key things. For p-aminobenzenesulfonamide, it is necessary to carefully select its purity and properties to ensure flawless. The same is true for 2-chlorothiazole. The purity needs to be high and impurities must be removed before it can lay the foundation for subsequent reactions. When
is prepared, in a clean vessel, mix p-aminobenzenesulfonamide with 2-chlorothiazole in a certain proportion. Then add an appropriate amount of solvent. The choice of this solvent is related to the success or failure of the reaction. Polar organic solvents are often preferred, which can make the raw materials evenly dispersed and promote the progress of the reaction.
Then, slowly heat, and temperature control is essential. Do not overheat, causing the raw materials to decompose; nor overcool, making the reaction slow. It needs to be maintained in a specific temperature range, usually at a moderate high temperature, but also fine-tuned according to specific circumstances. When heating, constantly stir to make the raw materials fully contact and react evenly. < Br >
During the reaction, there may be side reactions, so close observation is required. If there is any abnormal color, taste, and state change, it should be disposed of in time. Appropriate reagents can be used to inhibit side reactions and ensure smooth reaction.
After the reaction is completed, the product needs to go through the process of separation and purification. Filtration, extraction, etc. to remove impurities to obtain pure 2-sulfamethiazole. When filtering, select a suitable filter material to make solid-liquid separation complete. Extraction uses a suitable extractant to extract the product from the mixture.
At the end, the obtained product is tested in detail. Observe its appearance, measure its purity, and test its structure to ensure that it meets the required standards. In this way, the qualified 2-sulfamethiazole was obtained.
What is the price range of 2-Sulfanilamidothiazole in the market?
I have not heard of the exact price of 2-Sulfanilamidothiazole in the market. However, the price of this product often changes for various reasons. The abundance of its raw materials, the difficulty of making the art, and the amount of need are all factors that affect the price. If the raw materials are abundant, the process is simple, and the need is not in stock, the price will be low; on the contrary, if the raw materials are scarce, the process is difficult, and the need to use a lot, the price will be high.
If you want to know the exact price, you can visit various pharmaceutical shops, chemical markets, or consult these industries. They often know the current market conditions and can tell the recent price. And the price also changes with the years, so you must always pay attention to changes in market conditions, in order to get an accurate price. Although it is difficult for me to understand the exact range, following this path, I will surely be able to get a close number.