2-(prop-2-yn-1-ylsulfanyl)-1,3-benzothiazole

2-%28prop-2-yn-1-ylsulfanyl%29-1%2C3-benzothiazole, this is an organic compound, its alias is 2- (propyl-2-alkynyl-1-ylthio) -1,3-benzothiazole. This substance has important uses in many fields.
In the field of medicinal chemistry, it is often used as a pharmaceutical intermediate. Due to the structure of alkynyl and benzothiazole, it has unique reactivity and biological activity, and can participate in various chemical reactions, which helps to synthesize complex compounds with specific pharmacological activities. Or it can be modified to meet the treatment needs of specific diseases and develop new drugs.
In the field of materials science, it can be used to prepare special functional materials. The alkynyl group can participate in the polymerization reaction to generate polymer materials with unique properties, such as materials with excellent optical, electrical properties or special mechanical properties, which are used in electronic devices, optical materials and other fields.
In organic synthetic chemistry, it is a key building block for the construction of complex organic molecules. With its reactivity of sulphur and alkynyl groups, it can carry out many reactions such as nucleophilic substitution and cyclization, and help to synthesize organic compounds with novel and complex structures, which contributes to the development of organic synthetic chemistry.
In addition, in the field of agricultural chemistry, or after reasonable modification, it can be used to develop new pesticides, such as fungicides, insecticides, etc., to escort agricultural production. In conclusion, 2- (propyl-2-alkynyl-1-ylthio) -1,3-benzothiazole is of great significance in many scientific fields and has a wide range of uses.

2-% (prop-2-yn-1-ylsulfanyl) -1,3-benzothiazole, this is an organic compound. Its physical properties are very important and are related to many chemical applications.
First, the appearance of this compound is usually solid, and its color is often white or white-like powder. This form is easy to store and use. In many chemical reactions, solid materials are easier to measure and operate.
Besides, the melting point is in a specific temperature range. The determination of the melting point is an important means to identify the purity of the compound. If the melting point range is narrow, it indicates that the purity of the compound is high. The melting point of this compound can help determine when it changes from solid to liquid during heating, which is crucial in synthesis, separation and purification. < Br >
Solubility is also a key physical property. It exhibits a certain solubility in organic solvents such as ethanol and dichloromethane. This solubility allows it to integrate into specific reaction systems and participate in various chemical reactions. However, in water, its solubility is very small. This property determines that when it comes to reactions or operations in the aqueous phase, its existence form and reactivity need to be carefully considered.
Density is also a property that cannot be ignored. Knowing its density allows for more accurate control of the dosage and ratio of materials when performing solution preparation, separation, etc.
In addition, the stability of this compound is also worthy of attention. Under normal environmental conditions, it has certain stability, but under high temperature, strong light or the presence of specific chemical reagents, decomposition or other chemical reactions may occur. This requires that specific specifications must be followed during storage and use to ensure that its chemical structure and properties do not change.
The physical properties of this compound have an important impact on its research, production and application in the field of chemistry, and these properties need to be fully considered during use.

2-% (prop-2-yn-1-ylsulfanyl) -1,3-benzothiazole is an organic compound with unique chemical properties. It contains a core structure of benzothiazole, and the sulfur atom is connected to the proparynyl group. This structure endows the compound with various chemical activities.
From the perspective of reactivity, the carbon-carbon triple bond in the proparynyl group is an active check point. Because the triple bond is rich in electrons, it is vulnerable to electrophilic attack, and an electrophilic addition reaction can occur. For example, when encountering hydrogen halide, a halogen atom is added to one end of the triple bond, and a hydrogen atom is added to the other end to form a haloolefin derivative.
Furthermore, this compound can participate in the cyclization reaction. Under suitable conditions, propyne groups react with specific groups on benzothiazole rings to form new cyclic structures, expanding the complexity of molecular structures and enriching their chemical properties, which are used in the field of organic synthesis to construct polycyclic compounds.
From the perspective of physical properties, the sulfur atoms and unsaturated bonds in the molecule affect the intermolecular forces. Generally speaking, its boiling point and melting point are affected by the synergistic action of various groups in the structure. Sulfur atoms increase intermolecular van der Waals forces, while unsaturated bonds affect the way molecules are piled up, causing their melting boiling points to be different from compounds with similar structures but without such groups.
In terms of solubility, the compound has low solubility in water due to the presence of hydrophobic groups such as benzene rings, but it is soluble in common organic solvents, such as dichloromethane, chloroform, tetrahydrofuran, etc. This property facilitates its operation and separation and purification in organic synthesis reactions.
In addition, due to the existence of a conjugated system, the compound may have certain optical properties. The conjugated structure enables the molecule to absorb specific wavelengths of light, exhibit color or have fluorescence properties, and has potential application value in optoelectronic devices, fluorescent probes and other fields.

To prepare 2 - (propyl-2-alkyne-1-ylthio) -1,3-benzothiazole, there are many methods, and the following are the main ones.
First, 1,3-benzothiazole-2-mercaptan can be reacted with propanyl halide in a base environment. Take an appropriate amount of 1,3-benzothiazole-2-mercaptan and put it in the reactor, add an appropriate amount of base, such as potassium carbonate, sodium carbonate, etc., to help the reaction proceed. The base can capture the hydrogen of 1,3-benzothiazole-2-mercaptan, making it a sulfur negative ion state, which greatly increases its activity. Then, slowly add propargyl halides, such as propargyl bromide and propargyl chloride. When the two meet, the sulfur negative ion nucleophilic attacks the carbon connected to the halogen atom of the propargyl halide, and the halogen ions leave, and then form 2- (propylene-2-acetylene-1-ylthio) -1,3-benzothiazole. When reacting, pay attention to the control of temperature, not too high or too low, too high will cause side reactions, and too low will cause slow reactions.
Second, propargyne mercaptan can also be used to react with 2-halo-1,3-benzothiazole. Take propargyne mercaptan first, and add an appropriate amount of base to activate it. The sulfur hydrogen bond of propargyne mercaptan is broken by the base, and the sulfur negative ion is generated. The halogen atom in 2-halo-1,3-benzothiazole has high activity, and the sulfur negative ion can attack it, and the halogen ion escapes to obtain the target product. In this process, the choice of solvent is also important. Commonly used organic solvents such as N, N-dimethylformamide (DMF), dichloromethane, etc., need to be selected according to the actual reaction, so that the reaction can go forward.
Third, the organometallic reagent method can also be used. For example, the preparation of alkynyl-containing organometallic reagents, such as alkynyl lithium reagent and alkynyl magnesium reagent. Taking the alkynyl lithium reagent as an example, the propynyl lithium is first prepared, and then it reacts with the sulfur-containing 1,3-benzothiazole derivative. The carbon linked to sulfur in the 1,3-benzothiazole derivative has a certain positive electricity, and the alkynyl negative ion of the alkynyl lithium reagent attacks this carbon nucleophilically, forming a carbon-sulfur bond to obtain 2 - (propyl-2-alkynyl-1-thio) -1,3-benzothiazole. However, the organometallic reagent has high activity, and the preparation and reaction need to be in a harsh environment without water and oxygen to prevent it from reacting with water and oxygen and causing deactivation or side reactions.

There is an exact price for 2 - (propylene-2-alkyne-1-ylthio) -1,3-benzothiazole in the market. However, to estimate its price, you need to refer to many reasons.
First look at the difficulty of preparing this product. If the synthesis method is complicated, the materials used are rare, the process is complicated and high-precision equipment and technology are required, resulting in a small output, the price will be high. If in the past, alchemy silver was not easy and the method was difficult to find, and its price was high.
The second look at the market's desire. If this 2- (propylene-2-alkyne-1-ylthio) -1,3-benzothiazole has a large demand in various fields such as medicine and chemical industry, and the supply is less and the demand is more, the price will also rise. Just like the grain in wartime, the demand is large and the supply is small, and the price will rise.
Furthermore, see if there are competing products. If there are other things that can replace 2- (propylene-2-alkyne-1-ylthio) -1,3-benzothiazole with similar performance, and the price is easy to take, the price is limited. Just like traveling today, there are many cars and many ways, and the price is self-balanced.
The origin and transportation are also affected. The origin is remote, the transportation is difficult, and the cost is high, and the price will also increase. For example, jewelry from the Western Regions, transported to the Central Plains, is very expensive and expensive.
In general, without detailed market conditions and production details, it is difficult to determine the exact price of 2 - (propylene-2-alkynyl-1-ylthio) -1,3-benzothiazole, and its price may fluctuate within a wide range due to the above reasons.