2-phenyl4-thiazolemethanamine

2-Phenyl4-thiazolemethanamine, Chinese name or 2-phenyl-4-thiazolemethanamine. This substance has a wide range of uses and is often the key raw material for the creation of new drugs in the field of medicine. Because thiazole and phenyl structures are common in many drugs, they have a variety of biological activities, such as antibacterial, anti-inflammatory, anti-tumor, etc. Taking antibacterial as an example, by adding suitable groups through specific chemical reactions, the drug can target specific metabolic links of bacteria and hinder the growth and reproduction of bacteria, which is of great significance for the treatment of bacterial infections.
In the field of materials science, it is also useful. Or it can be chemically modified and integrated into polymer materials as functional monomers. Due to its unique structure, or endowing materials with special properties such as good optical properties and thermal stability. For example, in the preparation of optical materials, its participation can optimize the light refraction and light absorption characteristics of materials to meet the specific needs of optical device manufacturing.
In the field of organic synthesis, 2-phenyl-4-thiazolamide, as an important intermediate, can undergo a variety of chemical reactions to construct more complex organic compounds. With the thiazole ring and benzene ring activity check point, substitution, addition and other reactions can be carried out, providing the possibility for the synthesis of organic molecules with diverse structures, promoting the development of organic synthesis chemistry, and exploring the structure and properties of novel organic compounds.

2-Phenyl4-thiazolemethanamine is an organic compound, its shape is mostly powder or crystalline, and its color is often nearly white or yellowish. This substance has specific chemical properties, which are related to its behavior in the reaction and its interaction with other substances.
From the structure, its benzene ring is connected to the thiazole ring by methylene, and the amine group is also attached to the methylene. The benzene ring gives the compound a certain stability and aromaticity, while the thiazole ring is endowed with unique electronic properties and reactivity due to nitrogen and sulfur atoms.
In terms of solubility, it behaves differently in organic solvents. Common organic solvents such as ethanol and dichloromethane can form intermolecular forces with compounds to help them dissolve due to their suitable polarity. However, the polarity of water is strong, and the polarity of 2-phenyl4-thiazolemethanamine does not match it, so the solubility in water is poor.
In terms of acidity and alkalinity, the amine group can accept protons and is weakly basic. In case of acid, the amine group is easy to combine with protons to form corresponding salts. This property is important in organic synthesis, and its solubility, reactivity, separation and purification can be controlled by acid-base reaction.
Reactivity is also a key property. The benzene ring can undergo electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. Thiazole ring can participate in reactions on the ring, such as nucleophilic substitution, and methylene is affected by benzene ring and thiazole ring, α-hydrogen has certain activity and can participate in related reactions. Amine groups can be used as nucleophiles to react with electrophilic reagents such as halogenated hydrocarbons and acid anhydrides to generate new amine compounds or amides.
2-phenyl4-thiazolemethanamine has complex and diverse chemical properties. In the fields of organic synthesis and medicinal chemistry, chemists can design reactions according to their properties to prepare desired compounds and explore potential biological activities and medicinal values.

There are various methods for synthesizing 2-phenyl-4-thiazolemethanamine. One method can also be obtained from a suitable starting material through a multi-step reaction.
First take the compound containing the benzene ring, make it meet the precursor containing sulfur and nitrogen heterocycles, and make it bond and combine under specific reaction conditions. This reaction may require a suitable catalyst to promote the smooth progress of the reaction. For example, select a metal salt as the catalyst, adjust the appropriate temperature, pressure and reaction time, so that the two undergo a reaction such as condensation, and initially construct the basic structure containing the benzene ring and thiazole ring.
Then, modify the obtained intermediate. At a specific position of the thiazole ring, an amine-containing substituent is introduced. This step may involve reactions such as nucleophilic substitution. After careful selection of reaction reagents, such as specific amination reagents, and optimization of the reaction environment, to ensure that the amine group is accurately attached to the 4-position of the thiazole ring, and to ensure that the carbon atom at this position is connected to the amine group, the final result is 2-phenyl-4-thiazolemethanamine.
Another method can first prepare the thiazolemethanamine ring parent, which is a small molecule containing sulfur and nitrogen. After cyclization, the thiazole ring is introduced into the 2-position of the thiazole ring. Afterwards, at the 4-position of the thiazole ring, a series of reactions are used to introduce the structure containing aminomethyl groups. In this process, the multi-step reactions such as halogenation and nucleophilic substitution are carefully regulated step by step to achieve the purpose of synthesizing 2-phenyl-4-thiazolemethanamine. The synthesis process requires careful study of the conditions of each step of the reaction, including the purity and dosage of the reagents used, the temperature of the reaction, and the pH, etc., all of which are related to the yield and purity of the product.

2-Phenyl-4-thiazolecarbamine is an organic compound that is of great significance in many fields of biological activity. There are many common derivatives, each with unique properties and potential applications.
One is derived from alkylation. In this process, the amino group of 2-phenyl-4-thiazolecarbamine reacts with alkylating agents such as haloalkanes or sulfates. If reacted with methyl iodine, N-methyl-2-phenyl-4-thiazolecarbamine can be obtained. The introduction of alkyl groups, or the change of lipophilicity of compounds, affects their transmembrane transport ability. In drug design, it may improve the permeability of drugs to biofilms and improve bioavailability.
The second is an acylated derivative. The reaction of acid chloride or anhydride with the amino group of 2-phenyl-4-thiazoleclamine can form an amide structure. For example, acetyl chloride reacts with it to form N-acetyl-2-phenyl-4-thiazoleclamine. Such derivatives may change in stability due to the presence of amide bonds, and their interaction patterns with targets in organisms may be different. In some biological activity screens, or exhibit unique activities.
Furthermore, 2-phenyl-4-thiazolomethylamine can form salt derivatives. React with inorganic acids such as hydrochloric acid, sulfuric acid, or organic acids such as acetic acid, citric acid, etc., to generate corresponding salts. For example, react with hydrochloric acid to obtain 2-phenyl-4-thiazolomethylamine hydrochloride. Salt derivatives usually have good solubility. In the development of formulations, they can improve the solubility of compounds and are easier to prepare into various dosage forms, such as injections, oral solutions, etc.
In addition, there are heterocyclic derivatives. The amino group of 2-phenyl-4-thiazolamide or other activity checking points on the thiazole ring can react with the reagent containing heteroatoms to construct a new heterocyclic structure. This heterocyclic modification may significantly change the electron cloud distribution and spatial structure of the compound, which in turn affects its biological activity and pharmacological properties, and may become a key structural transformation in the development of new drugs.

I don't know the price range of "2-phenyl4-thiazolemethanamine" in the market. This is a rather professional chemical substance, and its price is determined by many factors. For example, purity is one of the keys, and the price of high purity must be higher than that of low purity. The difficulty of the production process also has an impact. If the process is complicated and the cost increases, the price will rise. The market supply and demand situation cannot be ignored. When demand is strong and supply is scarce, the price will rise; on the contrary, if supply exceeds demand, the price may fall. In addition, the price of different manufacturers will vary due to differences in brands, quality control, etc.
To determine the price range, you can check the professional chemical reagent trading platform in detail, or consult the chemical reagent supplier. They can often provide more accurate price information based on real-time market conditions. It may also be helpful to refer to past transaction records, industry reports, etc. However, such information may be lagging behind and can only be used as a general reference.