2-(methylsulfanyl)-4,5-dihydro-1,3-thiazole

2-%28methylsulfanyl%29-4%2C5-dihydro-1%2C3-thiazole is 2- (methylthio) -4,5-dihydro-1,3-thiazole, which has a wide range of uses.
First, in the field of pharmaceutical synthesis, it is often used as a key intermediate. Due to the unique structure of this compound, it can introduce specific functional groups into drug molecules and endow drugs with unique biological activities. For example, in the synthesis of some antibacterial drugs, 2- (methylthio) -4,5-dihydro-1,3-thiazole is used as the starting material. After a series of chemical reactions, complex molecular structures with antibacterial efficacy are constructed to fight various bacteria and heal patients.
Second, it also plays an important role in the field of pesticide research and development. It can be used as a key component in the synthesis of new pesticides. Through rational molecular design and modification, pesticide products with high-efficiency poisoning effect on pests or good control effect on crop diseases can be prepared. These pesticides can effectively protect crops from pests and diseases, ensure agricultural harvests, and ensure food supply.
Third, in the field of materials science, 2 - (methylthio) -4,5 - dihydro-1,3 - thiazole also shows potential uses. It can participate in the synthesis of certain functional materials, such as special polymer materials. By copolymerizing with other monomers, materials are endowed with unique physical and chemical properties, such as improving the stability and solubility of materials or endowing them with specific optical and electrical properties, so as to meet the needs of different fields for special materials.
In summary, although 2- (methylthio) -4,5-dihydro-1,3-thiazole is an organic compound, it is of great value in many fields such as medicine, pesticides and materials science, and is of great significance to promote the development of various fields.

2-%28methylsulfanyl%29-4%2C5-dihydro-1%2C3-thiazole is 2- (methylthio) -4,5-dihydro-1,3-thiazole, which is an organic compound. Its physical properties are as follows:
Its shape is mostly colorless to light yellow liquid, and it is clear in appearance. Smell, it has a unique sulfur ether smell, or has a pungent feeling.
When it comes to solubility, it can be well miscible in organic solvents such as ethanol, ether, dichloromethane, etc. Due to the molecular structure of the compound, suitable intermolecular forces can be formed between the compound and the organic solvent, such as van der Waals force, hydrogen bond, etc., to help it dissolve. However, in water, its solubility is poor. Because water is a highly polar solvent, while 2- (methylthio) -4,5-dihydro-1,3-thiazole has a relatively weak polarity, it is difficult to dissolve in water according to the principle of "similar miscibility".
The boiling point is about a certain temperature range, and this value is closely related to the intermolecular force. In addition to the van der Waals force, the intermolecular may have weak sulfur-hydrogen bonds and other effects, which require specific energy to overcome the intermolecular attractive force and cause it to change from liquid to gaseous state, so the boiling point has a certain value.
In terms of melting point, it is usually also in a certain low temperature range. When the temperature drops to the melting point, the thermal motion of the molecules weakens, and the intermolecular force promotes its regular arrangement, and then solidifies from liquid to solid state. The density of
is slightly higher than that of water. Mix it with water and let it stand. It can be seen that it sinks to the bottom of the water. Due to the relative mass of the compound molecules and the way of molecular accumulation, the mass per unit volume is greater than that of water. The vapor pressure of
2- (methylthio) -4,5-dihydro-1,3-thiazole is relatively low at room temperature. Due to the relatively strong intermolecular force, the tendency of molecules to escape from the liquid surface to form steam is small. However, with the increase of temperature, the thermal motion of molecules intensifies, and the vapor pressure also increases accordingly.

2 - (methylthio) -4,5 -dihydro-1,3 -thiazole, which is a heterocyclic organic compound containing sulfur. Looking at its structure, the thiazole ring has unique stability. The sulfur and nitrogen atoms in the ring are conjugated, just like the ancient ring, interlocking each other, making the ring configuration stable.
In terms of its chemical activity, the existence of methylthio is crucial. The sulfur atom in methylthio has a lone pair of electrons, just like a warrior holding a spear, which is easy to launch a nucleophilic attack. When encountering electrophilic reagents, this methylthio group will charge ahead and react with it. In case of halogenated hydrocarbons, the sulfur atom of the methylthio group attacks the carbon atom of the halogenated hydrocarbon, and the halogen atom leaves, and a nucleophilic substitution reaction occurs to generate new sulfur-containing compounds. This reaction has a wide range of uses in organic synthesis, which can increase carbon chains or introduce specific functional groups.
Furthermore, although the double bond on the thiazole ring is unsaturated, its reactivity is slightly reduced due to the conjugation effect of the ring. If you want to perform an addition reaction on its double bond, you need to choose suitable reaction conditions and reagents. For example, under the action of a specific catalyst, it can be added to hydrogen to change the double bond into a single bond to form a saturated thiazole derivative. The physical and chemical properties of this derivative are quite different from those of the original compound.
In terms of acidity and alkalinity, the compound has a weak alkalinity due to the existence of nitrogen atoms, and can react with strong acids to form salts. It is like a softening, and the solitary pair of nitrogen atoms accepts protons, showing alkaline characteristics. However, this alkalinity is weaker than common organic bases. Because the conjugate system of the thiazole ring disperses the electron cloud, the binding force of the nitrogen atom to the proton decreases.
In short, the chemical properties of 2- (methylthio) -4,5-dihydro-1,3-thiazole are rich, and it is like a shining star in the fields of organic synthesis and medicinal chemistry, with potential application value.

2-%28methylsulfanyl%29-4%2C5-dihydro-1%2C3-thiazole that is 2- (methylthio) -4,5-dihydro-1,3-thiazole, let me give you a way to synthesize this compound.
One method is to use sulfur-containing raw materials to react with nitrogen-containing compounds. First, take an appropriate mercaptan, such as methyl mercaptan, and make it react with a suitable halogenated carbonyl compound, such as halogenated acetyl halides, in an alkaline environment. For alkalis, sodium hydroxide, sodium carbonate, etc. can be selected to maintain the appropriate pH of the reaction system and promote the smooth progress of the reaction. This step can lead to an intermediate containing sulfur and carbonyl.
Next, the intermediate interacts with ammonia or amine compounds. Nitrogen atoms in ammonia or amines are nucleophilic and can attack the carbonyl carbon of the intermediate, initiating a cyclization reaction in the molecule, and then forming the ring structure of 2- (methylthio) -4,5-dihydro-1,3-thiazole. During the reaction, the temperature and reaction time need to be carefully regulated. If the temperature is too high, it may cause an increase in side reactions; if the temperature is too low, the reaction rate will be delayed. Generally speaking, the reaction temperature is controlled between room temperature and moderate heating. The reaction time depends on the activity of the raw material and the scale of the reaction, ranging from a few hours to tens of hours.
There are other methods. Starting from the heterocyclic precursor containing sulfur and nitrogen, the target product is obtained by the transformation of functional groups. If a specific thiazoline derivative is selected, it can be modified by thiomethylation. Methylation reagents, such as iodomethane, dimethyl sulfate, etc., can be used to introduce methylthio at a specific position on the thiazoline ring under suitable reaction conditions, resulting in 2- (methylthio) -4,5-dihydro-1,3-thiazole. In this process, it is necessary to pay attention to the selectivity of the reaction to prevent unnecessary substitution at other positions. It can be regulated by selecting suitable catalysts, solvents, etc. Catalysts, or metal salts, organic bases, and solvents are selected depending on the solubility of the reactants and the reaction mechanism, such as polar aprotic solvents dimethylformamide, dimethylsulfoxide, etc., which help to carry out the reaction.

I cannot confirm that 2 - (methylthio) -4,5 -dihydro-1,3 -thiazole is in the market price range. This compound is not a well-known commodity, and its price is determined by many factors.
First, the difficulty of preparation is the key factor. If the synthesis of this compound requires complicated steps, special raw materials or harsh reaction conditions, the cost will be high, and the price will also rise. For example, rare catalysts or multiple steps of precision synthesis are required, which is time-consuming and laborious, and the price will not be low.
Second, the purity requirements have a great impact. High purity 2 - (methylthio) - 4,5 - dihydro - 1,3 - thiazole is more difficult to prepare, impurity removal requires exquisite technology and additional costs, so the price of high purity products is much higher than that of low purity.
Third, market supply and demand also affect the price. If there is a surge in demand for this compound in a certain field, but the supply is limited, such as a sudden increase in demand for specific pharmaceutical research and development or materials science applications, the price will rise; on the contrary, if there is little demand and sufficient supply, the price will decline.
Fourth, the sales channel is related to the purchase volume. Purchased through regular large chemical suppliers, the price may be higher due to quality assurance and service bonuses; bulk purchases often have discounts, and the unit price will be reduced.
Due to the lack of specific market surveys and data, it is difficult to give the exact price range. If you want to know more, you can consult chemical product suppliers, research chemical market reports or communicate in relevant professional forums to obtain more accurate price information.