2 Methyl Thiazole 4 Carboxylic Acid
quinoline thiophene imidazole thiazole

2-Methyl-thiazole-4-carboxylic acid

    Specifications

    HS Code

    221402

    Chemical Formula C5H5NO2S
    Molar Mass 143.164 g/mol
    Appearance Solid
    Color Typically white to off - white
    Odor May have a characteristic sulfur - containing odor
    Solubility In Water Poorly soluble
    Melting Point 172 - 176 °C
    Pka ~3.8 (approximate value for the carboxylic acid group)

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    General Information
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    Frequently Asked Questions

    As a leading 2-Methyl-thiazole-4-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 2-methyl-thiazole-4-carboxylic acid?
    2-% methyl-butyric acid-4-hexenyl ester has its important position in various fields such as daily chemical industry and food.
    In the field of daily chemical industry, it is often used as a fragrance. It has a unique aroma and can add a rich fragrance to all kinds of perfumes, aromatherapy products, air fresheners, etc. Or simulate natural floral and fruity aromas to create a pleasant atmosphere, improve the olfactory experience of the product, and make the user's body and mind happy. Taking perfumes as an example, perfumers skillfully match them with various fragrances. According to the needs of different fragrance types, they can either increase the fruity aroma and freshness, or add elegant floral fragrance, giving the perfume a unique charm and personality, making it stand out in the market.
    In the food industry, it is an important food additive. Can be used as edible spice to increase the aroma and flavor of food. In the production of beverages, candies, baked goods, etc., add an appropriate amount of this product according to the food flavor design. In fruit juice beverages, it can simulate the aroma of natural fruits, making the beverage more rich and pure; in baked goods, it can create an attractive aroma, enhance the attractiveness and taste of products, and satisfy consumers' pursuit of delicious food.
    2-methyl-butyric acid-4-hexenyl ester has made great contributions to the fields of daily chemical and food. With its unique aroma, it enhances product quality and market competitiveness, and adds fragrance to people's lives. It is of great value in industrial production and daily life.
    What are the physical properties of 2-methyl-thiazole-4-carboxylic acid?
    2-% methyl-pentanal-4-carboxylic acid, this substance is a class of organic compounds. Its physical properties are unique, with the following numbers:
    - ** Appearance and Properties **: Under normal conditions, it is mostly liquid or crystalline solids, but the exact form varies depending on the surrounding temperature, purity and other factors. In liquid state, it may have fluidity, while crystalline solids are relatively solid in texture and have a certain crystalline structure.
    - ** Odor **: Often emits a specific odor, either a weak aroma or a pungent odor. This odor originates from the functional groups contained in its molecular structure, such as aldehyde and carboxyl groups, which all affect its odor. < Br > - ** Melting point and boiling point **: The value of melting point and boiling point depends on the strength of intermolecular forces. Due to the presence of aldehyde groups and carboxyl groups in the molecule, intermolecular forces such as hydrogen bonds can be formed, resulting in relatively high melting points and boiling points. Specifically, the melting point or in a specific temperature range, at this temperature, the substance melts from solid to liquid; the boiling point also has corresponding values. When this temperature is reached, the liquid will transform into a gaseous state.
    - ** Solubility **: In water, the carboxyl group can form hydrogen bonds with water molecules, so it exhibits a certain solubility. However, the molecule also contains a hydrocarbon group part, which is hydrophobic, so it is not infinitely soluble in water. In organic solvents, such as ethanol, ether, etc., the solubility is better or better. Due to the principle of similar miscibility, the organic structure part is more affinity with organic solvents.
    - ** Density **: The density may be similar to that of water, or slightly different due to the specific molecular structure and relative mass of atoms. This characteristic is related to its distribution in the mixture. If the density is greater than that of water, it will be in the lower layer in the layered system; otherwise, it will be in the upper layer.
    What are the chemical properties of 2-methyl-thiazole-4-carboxylic acid?
    The chemical properties of 2-% methyl-pentanal-4-heptanoic acid are particularly important. This compound has the characteristics of both aldehyde and carboxyl groups.
    The aldehyde group has strong reductivity. It can react with Duolun reagent in a silver mirror. In an alkaline environment, the aldehyde group can reduce silver ions in silver hydroxide ammonia complex ions to metallic silver, which adheres to the wall of the container, just like a silver mirror. It can also react with Feilin reagent. The aldehyde group can transform blue copper hydroxide into brick red cuprous oxide precipitation, both of which are typical oxidation reactions of aldehyde groups and can be used to identify aldehyde substances. At the same time, the aldehyde group can be catalyzed to oxidize to a carboxyl group. If a suitable catalyst, such as copper or silver, is reacted with oxygen under heating conditions, the aldehyde group in 2% methyl-pentanal-4-heptanoic acid can be converted into a carboxyl group, which increases the number of carboxyl groups in the molecule.
    Furthermore, the carboxyl group also has its unique chemical properties. It is acidic and can be neutralized with bases. In case of sodium hydroxide, the carboxyl group will react with hydroxide ions to form the corresponding carboxylate and water. And it can undergo esterification reaction with alcohols. Under the condition of concentrated sulfuric acid as a catalyst and heating, the carboxyl group and the hydroxyl group of the alcohol are dehydrated and condensed to form an ester compound and water. This reaction is a reversible reaction.
    In addition, although the chemical properties of the hydrocarbon group in this compound are relatively stable, substitution reactions may occur under specific conditions, such as high temperature, light or with suitable catalysts, and the hydrogen atoms on the hydrocarbon group can be replaced by other atoms or atomic groups. In short, 2-% methyl-pentanal-4-heptanoic acid exhibits rich and diverse chemical properties due to the presence of aldehyde groups and carboxyl groups, which has important applications and research value in organic synthesis and related chemical fields.
    What are the synthesis methods of 2-methyl-thiazole-4-carboxylic acid?
    To prepare 2-methyl-butanol-4-carboxylic acid, there are three methods, all of which rely on ancient chemical skills and wisdom.
    First, it is based on the reaction of halogenated hydrocarbons. First, take a suitable halogenated hydrocarbon and make it react with metal magnesium to form a Grignard reagent. This reagent is very active and can react with carbon dioxide to introduce carboxyl groups. After hydrolysis, a carboxyl-containing compound can be obtained. Then with a suitable reducing agent, such as sodium borohydride or lithium aluminum hydride, the carbonyl group is reduced to a hydroxyl group, and then 2-methyl-butanol-4-carboxylic acid is obtained. This process is delicate, but it is necessary to pay attention to the control of reaction conditions, such as temperature, solvent, etc. If there is a slight difference in the pool, the product will not be pure. < Br >
    Second, take the reaction of aldol and ketone as the diameter. Choose an appropriate aldehyde or ketone to react with diethyl malonate under basic conditions. Diethyl malonate has an active methylene and can be condensed with the carbonyl of aldol and ketone. After hydrolysis, decarboxylation and other steps, the carboxyl part of the target compound can be obtained. After an appropriate reduction reaction, the carbonyl group is converted into a hydroxyl group to form 2-methyl-butanol-4-carboxylic acid. In this way, the ideal yield can be obtained by accurately grasping the amount of basic reagent and the reaction time.
    Third, the reaction of olefins is used as the method. Take a suitable olefin, and first introduce a halogen atom or other transformable group through an addition reaction. After that, through multi-step reactions, such as substitution, oxidation, etc., carboxyl and hydroxyl groups are gradually constructed. This process is complicated, and it requires familiarity with the reaction mechanism of each step. The reaction conditions are harsh, and the purity of the reactants is quite high.
    These three methods have their own advantages and disadvantages. Although the halogenated hydrocarbon method has clear steps, the preparation of Grignard reagents requires an anhydrous and oxygen-free environment, which is cumbersome to operate. The yield of the aldehyde-ketone method is good, but the reaction conditions are difficult to control. Although the olefin method can construct complex structures, there are many steps, and side reactions are easy to occur. The preparation of 2-methyl-butanol-4-carboxylic acid should be carefully selected according to the actual situation, such as the availability of raw materials, cost, equipment conditions, etc., in order to achieve the purpose of efficient preparation.
    What is the price range of 2-methyl-thiazole-4-carboxylic acid in the market?
    There are 2-methyl-pentanal-4-carboxylic acids in the market today, what is the price? This is a fine chemical, which has a wide range of uses and is used in medicine, chemical industry and other fields. Its price range is difficult to determine, due to the interaction of multiple factors.
    The first to bear the brunt is the cost of raw materials. The preparation of 2-methyl-pentanal-4-carboxylic acid requires specific raw materials. If raw materials are scarce or prices fluctuate, the price of the product will be implicated. For example, if the production of the raw materials depends on is reduced in case of natural disasters, or the supply is blocked due to the international situation, the price will rise.
    Furthermore, the complexity of the production process also affects the price. If a fine and complex process is required, such as multi-step reaction, strict temperature and pressure control, and strict equipment requirements, the production cost will be high, and the price will also rise.
    The state of market supply and demand is also the key. If there are many applicants, but there are few producers, it is in short supply, and the price will rise; on the contrary, if the market is saturated and the supply is excessive, the price will inevitably fall.
    In addition, the quality is also related to the price. High-purity, high-quality 2-methyl-pentanal-4-carboxylic acid, due to the difficulty of production and strict quality inspection, the price is often higher than that of ordinary ones.
    Roughly speaking, the average quality is several hundred yuan per kilogram; if the quality is high, it is used in high-end fields, and the spectrum per kilogram may reach several thousand yuan. However, this is only an approximate amount, and the actual price should be based on the specific market conditions and the manufacturer's pricing.