Chemical Formula | C6H9NS |
Appearance | Colorless to light yellow liquid |
Odor | Characteristic sulfur - containing odor |
Boiling Point | Approximately 175 - 177 °C |
Density | Around 1.05 g/cm³ |
Solubility In Water | Poorly soluble |
Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
Flash Point | Approximately 62 °C |
Stability | Stable under normal conditions |
Vapor Pressure | Low vapor pressure at room temperature |
What are the main uses of 2-Isopropylthiazole?
2-Isopropylthiazole is one of the organic compounds. It has a wide range of uses and plays an important role in many fields.
First, in the field of medicine, 2-isopropylthiazole is often a key intermediate for the synthesis of drugs. Due to the special structure of the thiazole ring, compounds are endowed with unique biological activities. On this basis, chemists can build complex drug molecular structures, and then develop new drugs with specific pharmacological effects, such as antibacterial, antiviral and anti-tumor drugs, to help humans fight various diseases.
Second, in the field of pesticides, this compound also has outstanding performance. It can be used as a raw material to prepare high-efficiency pesticides, which can effectively resist crop diseases and pests. With its chemical properties, it can precisely act on the specific physiological links of pests or pathogens, inhibit their growth and reproduction, ensure the healthy growth of crops, improve the yield and quality of crops, and ensure the stable development of agriculture.
Third, in the field of materials science, 2-isopropylthiazole also plays an important role. In some cases, it can participate in the synthesis of functional materials, giving materials such as special optical, electrical or mechanical properties. For example, in the preparation of some organic optoelectronic materials, the introduction of this compound can optimize the charge transfer performance of the material and improve the application efficiency of the material in optoelectronic devices (such as Light Emitting Diode, solar cells, etc.).
To sum up, 2-isopropylthiazoline has a unique structure and is an indispensable substance in many fields such as medicine, pesticides and materials science, which is of great significance for promoting the development of various fields.
What are the physical properties of 2-Isopropylthiazole?
2-Isopropylthiazole is one of the organic compounds. Its physical properties have many characteristics.
Looking at its properties, at room temperature, 2-isopropylthiazole is often colorless to light yellow liquid, with a clear and transparent appearance. It can be seen in sunlight with a slight glow, as if concealing a unique luster, just like the shimmer on the surface of an ancient mysterious treasure, which is fascinating to explore.
As for its smell, it exudes a special smell. Although it is not pungent and intolerable, it is also different from the ordinary fresh smell, as if it is a blend of various subtle smells, just like the ancient secret spice, exuding an indescribable unique charm.
When it comes to boiling point, it is about a specific temperature range, which is the critical value for its transformation from liquid to gas state. At this temperature, liquid molecules can break free from each other's shackles and rise into gaseous states, similar to the emergence and ascension of ancient immortals after they reached a certain level of cultivation. The characteristics of boiling point make 2-isopropylthiazole exhibit a unique physical transformation in a specific temperature environment.
Melting point is also an important physical property. At a certain low temperature, the activity of 2-isopropylthiazole molecules slows down, and they are arranged close to each other. They solidify from liquid to solid state, just like everything freezes in cold winter, forming an orderly lattice structure between molecules.
Its density also has a specific value, reflecting the mass of matter per unit volume. Density is like a measure of its "thickness" index, so that when 2-isopropylthiazole is mixed or interacted with other substances, it shows a different state according to this characteristic, as if in ancient art of war, soldiers are arranged according to the terrain, and each is in its place.
In terms of solubility, 2-isopropylthiazole has a certain solubility in specific organic solvents, and can blend with some solvents, just like the masters of different schools in ancient times fought and fused with each other to develop a wonderful scene; while its solubility in water is relatively limited, just like two different groups that do not cooperate with each other, and it is difficult to completely blend. This solubility characteristic determines its role and performance in various chemical processes and application scenarios.
What are the chemical properties of 2-Isopropylthiazole?
2-Isopropyl thiazole is one of organic compounds. It has unique chemical properties. Looking at its structure, the thiazole ring is based, and the isopropyl group is connected to it. This structure has a great influence on its properties.
On the physical properties, it may be liquid at room temperature and has a specific odor, but it needs to be determined experimentally. Its boiling point, melting point and other properties are related to the intermolecular force. The conjugate structure of the thiazole ring and the dislocation effect of the isopropyl group have their own characteristics of the intermolecular force, which affects the melting boiling point.
In terms of chemical properties, the thiazole ring has certain aromaticity and can undergo electrophilic substitution reaction. Due to the difference in electronegativity of nitrogen and sulfur atoms on the ring, the electron cloud distribution is uneven, and the specific position is active to electrophilic reagents. For example, it interacts with halogenated reagents, or halogenated reactions occur at suitable positions.
Isopropyl has a electron-inducing effect, which affects the electron cloud density of the thiazole ring, making the reaction activity different from that of thiazole itself. In electrophilic substitution, isopropyl is ortho, para-site or more reactive.
In addition, 2-isopropyl thiazole may participate in metal-catalyzed reactions. Thiazole ring nitrogen and sulfur atoms can be used as ligands to coordinate with metal ions to form complexes, which have potential uses in organic synthesis and other fields.
Due to its structure and properties, 2-isopropylthiazole may have applications in the fields of medicine, pesticides, materials, etc. Such as in the field of medicine, or drug design based on its structure; in the field of pesticides, or the development of new pesticides using its biological activity. In short, the exploration of its chemical properties is of great significance in many fields.
What is the production method of 2-Isopropylthiazole?
The preparation method of 2-isopropylthiazole, although the ancient book "Tiangong Kaiwu" does not specify this specific matter, it can be deduced according to the ancient chemical process ideas.
To prepare 2-isopropylthiazole, or it can be started from sulfur and nitrogen-containing raw materials. One method can make isopropyl-containing halogenated hydrocarbons, such as isopropyl chloride, react with sulfur-containing and nitrogen-containing compounds, such as thiocyanates, in a suitable solvent in a mild heating state. In this case, the solvent or alcohol, such as ethanol, can dissolve the halogenated hydrocarbon and thiocyanate, and its properties are relatively mild. When heated, the halogen atom of the halogenated hydrocarbon undergoes a nucleophilic substitution reaction with thiocyanate to form an intermediate containing sulfur and nitrogen with isopropyl group.
Then, the intermediate is cyclized. Or under acidic or basic catalysis, the sulfur and nitrogen atoms in the molecule interact to form a thiazole ring. If an acidic catalyst, such as dilute sulfuric acid, can promote intramolecular rearrangement and cyclization; if an alkaline catalyst, such as sodium hydroxide, can also initiate a similar cyclization process, but the reaction conditions may be different.
Another method, or it can be modified by isopropylation from the heterocyclic parent containing sulfur and nitrogen. For example, thiazole is used as the starting material, and under appropriate reaction conditions, it interacts with isopropylation reagents such as isopropyl lithium or isopropyl magnesium halide (Grignard reagent). In a low temperature, anhydrous and inert gas protected environment, hydrogen atoms at specific positions on the thiazole ring are substituted by isopropyl to obtain 2-isopropyl thiazole. This process requires fine control of the reaction temperature and reagent dosage to ensure that the isopropyl group is accurately substituted to the target position.
The preparation process requires good observation of the reaction phenomenon, precise temperature control, time control and material ratio, so that the reaction can proceed in the expected direction to obtain a relatively pure 2-isopropyl thiazole product.
What is the price range of 2-Isopropylthiazole in the market?
In today's world, it is not easy to know the price range of 2-isopropylthiazole in the market. These things may vary in price due to different origins, different quality, and changes in supply and demand.
In the past market transactions, the prices of various goods often relied on the negotiation of merchants and the measurement of the market. However, in today's market, commerce is complex, and although information is widely available, it is still necessary to explore in many ways if you want to obtain an accurate price.
There may be markets where it is difficult to obtain due to the difficulty of production, the precision of the materials used, and the high price, or the number of thousands of gold; or elsewhere, due to technological improvement, the output is gradually abundant, the price is slightly easier, and hundreds of gold can be obtained.
However, if you want to know the exact number, you need to ask the merchants specializing in this industry and the market of chemical materials, check the quotations of all parties in detail, and compare the transactions in different seasons to obtain the approximate price. And the market conditions are changing rapidly, and the current price may be different tomorrow. Therefore, if you want to obtain a real-time price, you must visit it frequently, and follow the changes in market conditions.