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What is the chemical structure of 2-Isopropyl-4 ((N-methyl) amino) methyl) thiazole hydrochloride 908591-25-3
2-Isopropyl-4- ((N-methyl) aminomethyl) thiazole hydrochloride (2-Isopropyl-4- ((N-methyl) aminomethyl) thiazole hydrochloride), its CAS number is 908591-25-3. The chemical structure of this compound is composed of a thiazole ring as the core framework. The thiazole ring is a five-membered heterocycle containing sulfur and nitrogen, with unique electron cloud distribution and chemical activity. At the second position of the thiazole ring, isopropyl is connected, and isopropyl is a branched alkyl structure. Because the carbon atoms are connected at a specific bond angle, they have a three-dimensional spatial structure, which has a great impact on the physical and chemical properties of the molecule, which can enhance the hydrophobicity and steric hindrance effect of the molecule.
At the fourth position of the thiazole ring, a (N-methyl) amino structure is connected through methylene. Methylene is a simple -CH -2 -structure and plays a connecting role. ( In the N-methyl) amino group, the nitrogen atom is connected to the methyl group, and the nitrogen atom has a solitary pair of electrons, which makes the amino group alkaline and can participate in many chemical reactions, such as salting with acids. This compound is in the form of hydrochloride. The formation of hydrochloride salts is due to the combination of the solitary pair electrons of the amino nitrogen atom with hydrogen ions in hydrochloric acid to form stable ionic bonds, which greatly changes the solubility and other physical properties of the original compound. Overall, this chemical structure endows the compound with specific chemical and physical properties, which may have unique applications in the fields of organic synthesis and pharmaceutical chemistry.
What are the main uses of 2-Isopropyl-4 ((N-methyl) amino) methyl) thiazole hydrochloride 908591-25-3
2-Isopropyl-4- ((N-methyl) amino) methyl) thiazole hydrochloride (CAS No. 908591-25-3), which has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to synthesize compounds with specific biological activities. Its unique chemical structure helps to build complex drug molecular structures, laying the foundation for the development of new drugs, or can act on specific targets, helping to develop drugs for the treatment of various diseases.
In the field of materials science, because of the specific functional groups in its structure, it may participate in the material modification process. It is introduced into the material system through chemical reactions to improve the physical and chemical properties of materials, such as improving material stability, solubility or imparting special optical and electrical properties, and is used in electronic materials, polymer materials and other fields.
In organic synthetic chemistry, it is often used as a special reagent to participate in diverse organic reactions. With its structural activity, it guides the reaction in a specific direction, realizes the regioselectivity or stereoselectivity of the target product, and helps to synthesize organic compounds with special structures and functions, and promotes the development of organic synthetic chemistry.
This compound plays an important role in many scientific fields. With the progress of science and technology, its potential uses may be further expanded and explored.
What are the physical properties of 2-Isopropyl-4 ((N-methyl) amino) methyl) thiazole hydrochloride 908591-25-3
2-Isopropyl-4- ((N-methyl) amino) methyl) thiazole hydrochloride (2-Isopropyl-4- ((N-methyl) amino) methyl) thiazole hydrochloride), its CAS number is 908591-25-3. The physical properties of this substance are the key to studying its properties.
Looking at its morphology, under normal temperature and pressure, it is mostly in a solid state, which is due to intermolecular forces and structural characteristics. Its color is usually white or almost white. In a pure state, the color is uniform and the texture is delicate. < Br >
When it comes to solubility, in polar solvents, such as water, there is a certain solubility because there are groups in the molecule that can form hydrogen bonds with water molecules. However, its solubility is not infinite, limited by the hydrophobic part of the molecule, that is, the existence of isopropyl and thiazole rings, so that its solubility in water has a certain range. In organic solvents, such as ethanol, methanol, etc., the solubility is better than water, because these organic solvents are more suitable for the intermolecular forces of the compound, which is conducive to dispersion and dissolution.
In terms of melting point, this compound has a specific melting point value, which is one of the important indicators for identifying its purity. The level of melting point depends on the interaction forces between molecules, including hydrogen bonds, van der Waals forces, etc. When heated to this melting point temperature, the molecule obtains enough energy to overcome the lattice energy, and the crystal structure begins to disintegrate, transforming from a solid state to a liquid state.
Density is also one of its physical properties. The density reflects the mass per unit volume and is closely related to the molecular structure. The degree of close arrangement of molecules, the type and number of atoms all affect the density value. The density of this compound has a fixed measurement value under specific conditions, which is of important reference value in practical applications such as material storage and transportation.
What is the synthesis method of 2-Isopropyl-4 ((N-methyl) amino) methyl) thiazole hydrochloride 908591-25-3
To prepare 2-isopropyl-4 ((N-methyl) amino) methyl) thiazole hydrochloride (CAS No. 908591-25-3), the following ancient method can be used.
First take appropriate starting materials, such as compounds containing thiazole structure and reagents with isopropyl and aminomethyl-related functional groups. In the ancient chemical method, when the reaction conditions are finely regulated. In the reactor, control the appropriate temperature, such as slow heating, to maintain the temperature at a certain range. This range needs to be precisely calibrated according to the raw materials and reaction characteristics. It should not cause the decomposition of the raw materials due to overheating, nor should it be too cold to stop the reaction. < Br >
The pH of the reaction system is also crucial, and it can be adjusted with acid-base reagents to ensure that the reaction environment meets the needs of the reaction. And a suitable solvent needs to be selected to make the raw materials and reagents fully compatible, which is conducive to the reaction. The properties of this solvent should be well compatible with both reactants and products.
During the reaction process, it is appropriate to monitor it by ancient methods, such as visually observing the color change of the reaction liquid, the formation of precipitation, etc., or using simple instruments to observe the change of its physical properties. After the reaction is completed, the pure product can be obtained by separation and purification. According to the properties of the product and impurities, distillation, crystallization, extraction and other methods can be used to remove the impurities and keep the essence, and finally obtain 2-isopropyl-4 ((N-methyl) amino) methyl) thiazole hydrochloride. The whole process requires strict adherence to ancient regulations and careful operation.
2-Isopropyl-4 ((N-methyl) amino) methyl) thiazole hydrochloride 908591-25-3 What are the safety precautions?
2-Isopropyl-4- ((N-methyl) amino) methyl) thiazole hydrochloride (CAS No.: 908591-25-3) This substance is related to safety, and all matters should be paid attention to in detail.
First, chemically, because it is in the form of hydrochloride, it is easy to react in case of alkali, so it is necessary to avoid mixing with alkaline substances, and the storage environment must be dry, if the moisture is too heavy, or hydrolysis and other changes, damage its quality. Second, in terms of toxicity, although there is no detailed study to disclose its exact toxicity, as a chemical compound, it must not be touched, inhaled or ingested at will. When operating, it is necessary to wear protective clothing, protective gloves and goggles, and the operation should be carried out in a well-ventilated place or in a fume hood to prevent dust inhalation. Third, stability and reactivity. The structure of the substance contains thiazole ring and amino group, and under specific conditions, it may have certain reactivity. When there is high temperature, open flame or strong oxidizing agent, it may be dangerous. Therefore, it should be stored away from heat sources, fire sources and strong oxidizing agents. Fourth, waste disposal should not be taken lightly and should not be discarded at will. It should follow the local chemical waste disposal regulations and be handled by professional institutions to prevent environmental pollution. In short, the treatment of this chemical substance needs to be rigorous and serious, and it should be operated according to norms to ensure safety.